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Condition: Diabetes Mellitus

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Total 6126 results found since Jan 2013.

MELAS Syndrome: How Stroke-like are the Stroke episodes? (P1.255)
Conclusions:Patients with MELAS syndrome may present with recurrent strokes in the arterial territory rather than SLEs. Clinicians should entertain the possibility of a mitochondrial disease in young patients with cryptogenic stroke and pursue appropriate diagnostic evaluations and treatment.Disclosure: Dr. Liaw has nothing to disclose. Dr. Lewis has nothing to disclose. Dr. Saini has nothing to disclose. Dr. Gultekin has nothing to disclose. Dr. Koch has nothing to disclose. Dr. Asdaghi has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Liaw, N., Lewis, R., Saini, V., Gultekin, S. H., Koch, S., Asdaghi, N. Tags: Genetic Stroke Syndromes, Biomarkers, and Translational/Basic Research Source Type: research

Impact of Stroke Location on Stroke Outcome (P7.147)
CONCLUSIONS:Selective involvement of cortex or subcortical areas of brain due to ischemic stroke did not correlate with functional outcome at 3 months following thrombolysis. Patients with diabetes mellitus were more likely to have cortical strokes than subcortical strokes.Study Supported by:NoneDisclosure: Dr. Hinduja has nothing to disclose. Dr. Limaye has nothing to disclose. Dr. Patel has nothing to disclose. Dr. Mahuwala has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Hinduja, A., Limaye, K., Patel, A., Mahuwala, Z. Tags: Cerebrovascular Disease and Interventional Neurology: Predictors of Outcome After Ischemic Stroke Source Type: research

Drivers of Costs Associated With Reperfusion Therapy in Acute Stroke: The Interventional Management of Stroke III Trial Clinical Sciences
Conclusions— Minimizing the time to start of intravenous tPA and decreasing the use of routine general anesthesia may improve the cost-effectiveness of medical and endovascular therapy for acute stroke. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT00359424.
Source: Stroke - May 27, 2014 Category: Neurology Authors: Simpson, K. N., Simpson, A. N., Mauldin, P. D., Hill, M. D., Yeatts, S. D., Spilker, J. A., Foster, L. D., Khatri, P., Martin, R., Jauch, E. C., Kleindorfer, D., Palesch, Y. Y., Broderick, J. P., for the IMS III Investigators Tags: Thrombolysis Clinical Sciences Source Type: research

Adherence to Third European Cooperative Acute Stroke Study 3- to 4.5-Hour Exclusions and Association With Outcome: Data From Get With The Guidelines-Stroke Clinical Sciences
Conclusions— Patients with ECASS III–specific exclusion criteria for the >3 to 4.5 hours window are frequently treated with tPA. The presence of the additional exclusion criteria was not associated with worse outcomes in the >3 to 4.5 hours window compared with the 0 to 3 hours window.
Source: Stroke - August 25, 2014 Category: Neurology Authors: Cronin, C. A., Sheth, K. N., Zhao, X., Messe, S. R., Olson, D. M., Hernandez, A. F., Bhatt, D. L., Schwamm, L. H., Smith, E. E. Tags: Acute Cerebral Infarction, Thrombolysis Clinical Sciences Source Type: research

Incidence, Trends, and Predictors of Ischemic Stroke 1 Year After an Acute Myocardial Infarction Clinical Sciences
Conclusions— The risk of ischemic stroke within a year after myocardial infarction is substantial but has clearly been reduced during the studied time period. The major predictive factors found to correlate well with previous investigations. Reperfusion treatment, thrombocyte aggregation inhibition, and lipid lowering are the main contributors to the observed risk reduction.
Source: Stroke - October 27, 2014 Category: Neurology Authors: Ulvenstam, A., Kajermo, U., Modica, A., Jernberg, T., Soderstrom, L., Mooe, T. Tags: Platelet function inhibitors, Acute myocardial infarction, Acute Cerebral Infarction, Platelets Clinical Sciences Source Type: research

Web-based tool for dynamic functional outcome after acute ischemic stroke and comparison with existing models
Background: Acute ischemic stroke (AIS) is one of the leading causes of death and adult disability worldwide. In the present study, we aimed to develop a web-based risk model for predicting dynamic functional status at discharge, 3-month, 6-month, and 1-year after acute ischemic stroke (Dynamic Functional Status after Acute Ischemic Stroke, DFS-AIS). Methods: The DFS-AIS was developed based on the China National Stroke Registry (CNSR), in which eligible patients were randomly divided into derivation (60%) and validation (40%) cohorts. Good functional outcome was defined as modified Rankin Scale (mRS) score???2 at discharge...
Source: BMC Neurology - November 25, 2014 Category: Neurology Authors: Ruijun JiWanliang DuHaipeng ShenYuesong PanPenglian WangGaifen LiuYilong WangHao LiXingquan ZhaoYongjun WangOn behalf of China National Stroke Registry (CNSR) investigators Source Type: research

Risk of ischemic stroke during periods of warfarin discontinuation for surgical procedures: A longitudinal study of 4060 patients with atrial fibrillation (P1.058)
CONCLUSIONS: The risk associated with discontinuation of warfarin for procedures must be recognized and considered in the risk benefit analysis of any procedure.Disclosure: Dr. Jahangir has nothing to disclose. Dr. Malik has nothing to disclose. Dr. Suri has nothing to disclose. Dr. Qureshi has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Jahangir, N., Malik, A., Suri, M., Qureshi, A. Tags: Cerebrovascular Disease and Interventional Neurology: Atrial Fibrillation and Cardio-embolic Stroke Source Type: research

Elevated Total Homocysteine Levels in Acute Ischemic Stroke Are Associated With Long-Term Mortality Clinical Sciences
Conclusions— Our findings suggest that elevated tHcy levels in the acute phase of an ischemic stroke can predict mortality, especially in stroke patients with the large-vessel atherosclerosis subtype.
Source: Stroke - August 24, 2015 Category: Neurology Authors: Shi, Z., Guan, Y., Huo, Y. R., Liu, S., Zhang, M., Lu, H., Yue, W., Wang, J., Ji, Y. Tags: Acute Cerebral Infarction Clinical Sciences Source Type: research

Glycemic Variability and Functional Outcome After Acute Ischemic Stroke (P1.191)
Conclusions: An elevated GV on day 1 was significantly associated with worse functional outcome in patients with ischemic stroke. GV could be an important therapeutic target in the early management of acute ischemic stroke.Disclosure: Dr. Camara-Lemarroy has nothing to disclose. Dr. González-Moreno has nothing to disclose. Dr. Garza-Villarreal has nothing to disclose. Dr. Treviño-Herrera has nothing to disclose. Dr. Tena-Montiel has nothing to disclose. Dr. Muruet has nothing to disclose. Dr. Gongora Rivera has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Camara-Lemarroy, C., Gonzalez-Moreno, E., Garza-Villarreal, E., Trevino-Herrera, A., Tena-Montiel, R., Muruet, W., Gongora Rivera, J. Tags: Ischemic Stroke Outcomes Source Type: research

Aspirin for Stroke Prevention in Elderly Patients With Vascular Risk Factors: Japanese Primary Prevention Project Clinical Sciences
Conclusions— Aspirin did not show any net benefit for the primary prevention of stroke in elderly Japanese patients with risk factors for stroke, whereas age >70 years, smoking, and diabetes mellitus were risk factors for stroke regardless of aspirin treatment. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT00225849.
Source: Stroke - May 22, 2016 Category: Neurology Authors: Uchiyama, S., Ishizuka, N., Shimada, K., Teramoto, T., Yamazaki, T., Oikawa, S., Sugawara, M., Ando, K., Murata, M., Yokoyama, K., Minematsu, K., Matsumoto, M., Ikeda, Y., on behalf of the JPPP Study Group Tags: Cardiovascular Disease, Primary Prevention, Race and Ethnicity, Risk Factors Clinical Sciences Source Type: research

Validation of a Modified CHA2DS2-VASc Score for Stroke Risk Stratification in Asian Patients With Atrial Fibrillation: A Nationwide Cohort Study Clinical Sciences
Conclusions— In this Asian atrial fibrillation cohort, the mCHA2DS2-VASc score performed better than the CHA2DS2-VASc and would further identify atrial fibrillation patients who may derive a positive net clinical benefit from oral anticoagulation.
Source: Stroke - September 25, 2016 Category: Neurology Authors: Chao, T.-F., Lip, G. Y. H., Liu, C.-J., Tuan, T.-C., Chen, S.-J., Wang, K.-L., Lin, Y.-J., Chang, S.-L., Lo, L.-W., Hu, Y.-F., Chen, T.-J., Chiang, C.-E., Chen, S.-A. Tags: Atrial Fibrillation Clinical Sciences Source Type: research

Outcomes of Thrombolytic Treatment for Acute Ischemic Stroke in Dialysis Dependant Patients in the United States (S02.003)
CONCLUSIONS: The three fold higher odds of in-hospital mortality associated with administration of IV thrombolytics in dialysis dependant patients who present with acute ischemic stroke warrants a careful assessment of risk benefit ratio in this population.Disclosure: Dr. Adil has nothing to disclose. Dr. Adil has nothing to disclose. Dr. Irfan has nothing to disclose. Dr. Chaudhry has nothing to disclose. Dr. ATACH Investigators has nothing to disclose.
Source: Neurology - February 14, 2013 Category: Neurology Authors: Tariq, N., Adil, M., Irfan, M., Chaudhry, S., Qureshi, A. Tags: S02 Acute Stroke Therapy Source Type: research

Paradoxical Association of Smoking With In-Hospital Mortality Among Patients Admitted With Acute Ischemic Stroke Stroke
Conclusions Similar to myocardial ischemia, smoking was independently associated with lower inpatient mortality in acute ischemic stroke. This effect may be due to tobacco-induced changes in cerebrovascular vasoreactivity, or may be due in part to residual confounding. Larger, multicenter studies are needed to confirm the finding and the effect on 30-day and 1-year mortality.
Source: JAHA:Journal of the American Heart Association - June 19, 2013 Category: Cardiology Authors: Ali, S. F., Smith, E. E., Bhatt, D. L., Fonarow, G. C., Schwamm, L. H. Tags: Stroke Source Type: research

Glycosylated Hemoglobin A1 Predicts Risk for Symptomatic Hemorrhage After Thrombolysis for Acute Stroke Clinical Sciences
Conclusions— In our study, HbA1c turns out to be an important predictor of sICH after thrombolysis for acute stroke. These results suggest that hemorrhage after thrombolysis may be a consequence of long-term vascular injury rather than of acute hyperglycemia, and that HbA1c may be a better predictor than acute blood glucose or a history of diabetes mellitus.
Source: Stroke - July 22, 2013 Category: Neurology Authors: Rocco, A., Heuschmann, P. U., Schellinger, P. D., Kohrmann, M., Diedler, J., Sykora, M., Nolte, C. H., Ringleb, P., Hacke, W., Juttler, E. Tags: Acute Cerebral Infarction, Thrombolysis Clinical Sciences Source Type: research

Differences in Outcome and Predictors Between Ischemic and Intracerebral Hemorrhage: The South London Stroke Register Clinical Sciences
Conclusions— ICH has poorer outcomes up to 5 years after stroke. The improvement of functional outcome up to 3 months was significantly greater with ICH. Identification of factors associated with poor outcome may be used for clinical predictions.
Source: Stroke - July 22, 2013 Category: Neurology Authors: Bhalla, A., Wang, Y., Rudd, A., Wolfe, C. D. A. Tags: Acute Cerebral Hemorrhage, Acute Cerebral Infarction Clinical Sciences Source Type: research