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Condition: Cerebral Palsy

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Total 550 results found since Jan 2013.

Bihemispheric alterations in myelination in children following unilateral perinatal stroke
ConclusionMyelination of apparently uninjured brain in both the ipsilesional and contralesional hemispheres is decreased after perinatal stroke. Differences appear to radiate outward from the lesion. Further study is needed to determine clinical significance.
Source: NeuroImage: Clinical - July 19, 2018 Category: Radiology Source Type: research

Thalamic diaschisis following perinatal stroke is associated with clinical disability
ConclusionBilateral thalamic volume changes occur after perinatal stroke. Ipsilesional volume loss is not associated with clinical motor function. Contralesional volume is inversely correlated with clinical motor function, suggesting the thalamus is involved in the known developmental plasticity that occurs in the contralesional hemisphere after early unilateral injury.
Source: NeuroImage: Clinical - January 5, 2019 Category: Radiology Source Type: research

Pediatric stroke rehabilitation: A review of techniques facilitating motor recovery
Conclusion Rehabilitation of motor deficits following paediatric stroke remains understudied, but a number of promising therapies are emerging.
Source: Annals of Physical and Rehabilitation Medicine - September 20, 2016 Category: Rehabilitation Source Type: research

Self-management programmes for people post stroke: a systematic review.
Conclusions:This review provides some preliminary support for the potential importance of self-management interventions after stroke. The most appropriate content and best approach for delivery of these interventions remains to be determined. Further high-quality randomized controlled trials are needed to test the feasibility, acceptability, and efficacy of stroke self-management programmes. PMID: 23543340 [PubMed - as supplied by publisher]
Source: Clinical Rehabilitation - March 29, 2013 Category: Rehabilitation Authors: Lennon S, McKenna S, Jones F Tags: Clin Rehabil Source Type: research

Neurodevelopmental outcome after neonatal perforator stroke
AimTo assess outcome after neonatal perforator stroke in the largest cohort to date. MethodSurvivors from a cohort of children diagnosed with neonatal perforator stroke using cranial ultrasound or magnetic resonance imaging were eligible for inclusion. Recovery and Recurrence Questionnaire score, presence of cerebral palsy (CP), and crude outcome were assessed, specifically (1) the ability to walk independently, (2) participation in regular education, and (3) the presence of epilepsy. ResultsThirty‐seven patients (20 males, 17 females) aged 3 to 14 years (mean age 8y) were included in the study: 14 with isolated single ...
Source: Developmental Medicine and Child Neurology - July 27, 2015 Category: Child Development Authors: Ginette M Ecury‐Goossen, Marit Haer, Liesbeth S Smit, Monique Feijen‐Roon, Maarten Lequin, Rogier C J Jonge, Paul Govaert, Jeroen Dudink Tags: Original Article Source Type: research

Robotic Quantification of Position Sense in Children With Perinatal Stroke
Conclusions. Robotic assessment of position sense is feasible in children with perinatal stroke. Impairment is common and worse in arterial lesions. Limited correction with vision suggests cortical sensory network dysfunction. Disordered position sense may represent a therapeutic target in hemiparetic cerebral palsy.
Source: Neurorehabilitation and Neural Repair - August 8, 2016 Category: Neurology Authors: Kuczynski, A. M., Dukelow, S. P., Semrau, J. A., Kirton, A. Tags: Clinical Research Articles Source Type: research

Children with perinatal stroke are at increased risk for autism spectrum disorder: Prevalence and co-occurring conditions within a clinically followed sample
DISCUSSION: Children with perinatal stroke have an increased prevalence of ASD (11.4%) than in the general population. ASD concerns arise at a similar age as the general population, yet ASD is diagnosed almost two years later than the general population and 3.60 years after first concerns present. Co-occurring neurological conditions are common. Clinicians must be aware of increased prevalence and implement screening as part of routine care for all pediatric patients with perinatal stroke.PMID:34308766 | DOI:10.1080/13854046.2021.1955150
Source: The Clinical Neuropsychologist - July 26, 2021 Category: Psychiatry & Psychology Authors: Taralee Hamner Evelyn Shih Rebecca Ichord Lauren Krivitzky Source Type: research

Perinatalis stroke: vizsg álati irányelv
Orv Hetil. 2022 Jun 12;163(24):952-960. doi: 10.1556/650.2022.32472. Print 2022 Jun 12.ABSTRACTPerinatal stroke encompasses a heterogenous group of neurological syndromes due to cerebrovascular diseases, leading to chronic neurological sequelae in most of the cases. Based on pathophysiology, strokes are classified as perinatal arterial ischemic stroke, cerebral sinovenous thrombosis and perinatal haemorrhagic stroke. If not recognized in the neonatal period, the condition usually presents with focal asymmetry between 4-8 months of age and is referred to as presumed perinatal stroke. Nowadays, the increased utilization of m...
Source: Orvosi Hetilap - July 27, 2022 Category: General Medicine Authors: Eszter Vojcek Istv án Seri Source Type: research

A novel reproducible model of neonatal stroke in mice: Comparison with a hypoxia-ischemia model.
Abstract Neonatal stroke occurs in 1/4000 live births and leaves life-long neurological impairments, such as cerebral palsy and epilepsy. Currently, the rodent models of neonatal stroke that are available exhibit significant inter-animal variability, which makes it difficult to accurately assess the mechanisms of brain injury and the efficacy of candidate treatments. We aimed to introduce a novel, highly reproducible model of stroke, middle cerebral artery occlusion (MCAO), in immature mice, and to evaluate the reproducibility of this model compared with a conventional hypoxia-ischemia (HI) model. Postnatal day 12...
Source: Experimental Neurology - May 4, 2013 Category: Neurology Authors: Tsuji M, Ohshima M, Taguchi A, Kasahara Y, Ikeda T, Matsuyama T Tags: Exp Neurol Source Type: research

Does gait analysis change clinical decision-making in post-stroke patients? Results from a pragmatic prospective observational study.
CONCLUSION: GA significantly influences the therapeutic planning and reinforces decision--making for chronic post--stroke patients. Further work should be done to better translate GA results into indications for specific physiotherapy. CLINICAL REHABILITATION IMPACT: the use of GA as a tool to better define the rehabilitation planning in post--stroke patients should be fostered, particularly when surgery or botulinum toxin are considered and/or the prescription of orthoses is hypothesised. PMID: 25184798 [PubMed - as supplied by publisher]
Source: European Journal of Physical and Rehabilitation Medicine - September 3, 2014 Category: Rehabilitation Authors: Ferrarin M, Rabuffetti M, Bacchini M, Casiraghi A, Castagna A, Pizzi A, Montesano A Tags: Eur J Phys Rehabil Med Source Type: research

Risk of stroke among patients with cerebral palsy: a population‐based cohort study
AimThe aim of the study was to investigate the risk of stroke in patients with cerebral palsy (CP), based on nationwide data in Taiwan. MethodThis prospective cohort study was comprised of patients recorded on the Taiwan Longitudinal Health Insurance Database 2005 (LHID2005) who had a diagnosis of CP (n=1975) in records between 1 January 2004 and 31 December 2007. A comparison group (1:5) drawn from the same database was matched for age and sex (n=9875). Each patient was tracked by data until the development of stroke or the end of 2008. Cox proportional‐hazards regression analysis was used to evaluate the hazard ratios ...
Source: Developmental Medicine and Child Neurology - June 27, 2016 Category: Child Development Authors: Chin‐Wen Wu, Shih‐Wei Huang, Jia‐Wei Lin, Tsan‐Hon Liou, Lin‐Chuan Chou, Hui‐Wen Lin Tags: Original Article Source Type: research