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Condition: Hypertension

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Total 16251 results found since Jan 2013.

Antiplatelet Strategies and Outcomes in Patients with Noncardioembolic Ischemic Stroke from a Real-World Study with a Five-Year Follow-Up
In conclusion, clopidogrel is suggested for patients with an ESRS >  3 and aspirin for patients with an ESRS ≤ 3 for the secondary prevention of noncardioembolic ischemic stroke in Chinese patients.
Source: Translational Stroke Research - December 30, 2016 Category: Neurology Source Type: research

Strokes Associated With Pregnancy and Puerperium Clinical Sciences
Conclusions—The incidence of pregnancy-associated stroke in Japan did not seem higher than that in other Asian and Western countries. The proportion of hemorrhagic stroke among Japanese women was much higher than that in white women. Preexisting cerebrovascular diseases and reversible cerebral vasoconstriction syndrome play a key role in hemorrhagic and ischemic stroke, respectively.
Source: Stroke - January 22, 2017 Category: Neurology Authors: Kazumichi Yoshida, Jun C. Takahashi, Yohei Takenobu, Norihiro Suzuki, Akira Ogawa, Susumu Miyamoto Tags: Epidemiology, Pregnancy, Cerebrovascular Disease/Stroke Original Contributions Source Type: research

Gender Differences in Post Stroke Fatigue (P5.290)
Conclusions:In our urban predominately minority cohort, women had more severe PSF than men. The basis for the protective effect of HTN on PSF severity is unclear and deserves further study.Disclosure: Dr. Balucani has nothing to disclose. Dr. Gilles has nothing to disclose. Dr. Singer has nothing to disclose. Dr. Stefanov has nothing to disclose. Dr. Halket has nothing to disclose. Dr. Mlastabi has nothing to disclose. Dr. Huang has nothing to disclose. Dr. Weingast has nothing to disclose. Dr. Levine has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Balucani, C., Gilles, N., Singer, J., Stefanov, D., Halket, D., Mlastabi, J., Huang, A., Weingast, S., Levine, S. Tags: Stroke Recovery and Rehabilitation Source Type: research

Disruption of the Blood-Ocular Barriers in Stroke Patients (S8.008)
Conclusions:GLOS is common in stroke patients regardless of whether they receive treatment. BBB disruption appears to associate with blood-ocular barrier disruption. Whether these findings are due to the acute stroke, or merely due to a common underlying chronic process, remains to be determined.Disclosure: Dr. Hitomi has nothing to disclose. Dr. Latour has nothing to disclose. Dr. Leigh has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Hitomi, E., Latour, L. L., Leigh, R. Tags: Cerebrovascular Disease and Interventional Neurology: Acute Stroke Treatment Source Type: research

Characteristics and Outcomes among Patients Transferred to Regional Stroke Centers across the United States for Specialized Stroke Care (S25.007)
Conclusions:Many hospitals receive high volumes of ischemic stroke patients via transfer. Because transfer-in patients have worse outcomes, these transfer-in patients have the potential to negatively influence institutional outcomes rates. Transfer-in patients should be carefully accounted for in risk adjusted models of hospital outcomes.Disclosure: Dr. Ali has nothing to disclose. Dr. Fonarow has received personal compensation for activities with UCLA as an employee. Dr. Fonarow has received research support from NIH. Dr. Smith has nothing to disclose. Dr. Liang has nothing to disclose. Dr. Xian has nothing to disclose. D...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Ali, S., Fonarow, G., Smith, E., Liang, L., Xian, Y., Bhatt, D., Schwamm, L. Tags: Cerebrovascular Disease and Interventional Neurology: Prehospital and Emergency Department Ischemic Stroke Care Source Type: research

Uric Acid Treatment After Stroke Prevents Long-Term Middle Cerebral Artery Remodelling and Attenuates Brain Damage in Spontaneously Hypertensive Rats
AbstractHypertension is the most important modifiable risk factor for stroke and is associated with poorer post-stroke outcomes. The antioxidant uric acid is protective in experimental normotensive ischaemic stroke. However, it is unknown whether this treatment exerts long-term protection in hypertension. We aimed to evaluate the impact of transient intraluminal middle cerebral artery (MCA) occlusion (90  min)/reperfusion (1–15 days) on brain and vascular damage progression in adult male Wistar-Kyoto (WKY;n = 36) and spontaneously hypertensive (SHR;n = 37) rats treated (i.v./120 min post-occlusion) with uric aci...
Source: Translational Stroke Research - September 15, 2018 Category: Neurology Source Type: research

CYP2C19 Loss-of-Function Associated with First-Time Ischemic Stroke in Non-surgical Asymptomatic Carotid Artery Stenosis During Clopidogrel Therapy
This study measures effect ofCYP2C19 genotype on ischemic stroke risk during clopidogrel therapy for asymptomatic, extracranial carotid stenosis patients. Using deidentified electronic health records, patients were selected for retrospective cohort using administrative code for carotid stenosis, availability ofCYP2C19 genotype result, clopidogrel exposure, and established patient care. Patients with intracranial atherosclerosis, aneurysm, arteriovenous malformation, prior ischemic stroke, or observation time<1 month were excluded. Dual antiplatelet therapy patients were included. Patients with carotid endarterectomy or ...
Source: Translational Stroke Research - February 21, 2021 Category: Neurology Source Type: research

Outcomes of Thrombolytic Treatment for Acute Ischemic Stroke in Dialysis Dependant Patients in the United States (S02.003)
CONCLUSIONS: The three fold higher odds of in-hospital mortality associated with administration of IV thrombolytics in dialysis dependant patients who present with acute ischemic stroke warrants a careful assessment of risk benefit ratio in this population.Disclosure: Dr. Adil has nothing to disclose. Dr. Adil has nothing to disclose. Dr. Irfan has nothing to disclose. Dr. Chaudhry has nothing to disclose. Dr. ATACH Investigators has nothing to disclose.
Source: Neurology - February 14, 2013 Category: Neurology Authors: Tariq, N., Adil, M., Irfan, M., Chaudhry, S., Qureshi, A. Tags: S02 Acute Stroke Therapy Source Type: research

Paradoxical Association of Smoking With In-Hospital Mortality Among Patients Admitted With Acute Ischemic Stroke Stroke
Conclusions Similar to myocardial ischemia, smoking was independently associated with lower inpatient mortality in acute ischemic stroke. This effect may be due to tobacco-induced changes in cerebrovascular vasoreactivity, or may be due in part to residual confounding. Larger, multicenter studies are needed to confirm the finding and the effect on 30-day and 1-year mortality.
Source: JAHA:Journal of the American Heart Association - June 19, 2013 Category: Cardiology Authors: Ali, S. F., Smith, E. E., Bhatt, D. L., Fonarow, G. C., Schwamm, L. H. Tags: Stroke Source Type: research

Smoking and Hemorrhagic Stroke Mortality in a Prospective Cohort Study of Older Chinese Clinical Sciences
Conclusions— Smoking is strongly associated with hemorrhagic stroke mortality, particularly for subarachnoid hemorrhage.
Source: Stroke - July 22, 2013 Category: Neurology Authors: Xu, L., Schooling, C. M., Chan, W. M., Lee, S. Y., Leung, G. M., Lam, T. H. Tags: Acute Cerebral Hemorrhage Clinical Sciences Source Type: research

Glycosylated Hemoglobin for Diagnosis of Prediabetes in Acute Ischemic Stroke Patients
Background: Prediabetes (PD) is an independent risk factor for stroke. The American Diabetes Association (ADA) has recently published new guidelines recommending glycosylated hemoglobin A1c (HbA1c) as a marker to diagnose diabetes and PD. Diagnosis of diabetes Mellitus (DM) is often made at the time of hospitalization for stroke. Less is known about identifying PD in acute ischemic stroke (AIS) patients. We aim to investigate the frequency of new-onset PD in the hospitalized AIS patients using the new ADA guidelines.Methods: We retrospectively studied 362 AIS patients from our local database. Stroke risk factors, type of s...
Source: Journal of Stroke and Cerebrovascular Diseases - July 19, 2013 Category: Neurology Authors: Branko N. Huisa, Gulmohor Roy, Jorge Kawano, Ronald Schrader Tags: Original Articles Source Type: research

High Blood Pressure After Acute Ischemic Stroke Is Associated With Poor Clinical Outcomes: Fukuoka Stroke Registry Stroke and Blood Pressure
The relationship between the poststroke blood pressure (BP) and functional outcomes in patients with acute ischemic stroke is still controversial. The aim of the present study was to elucidate the impact of the poststroke BP on the clinical outcomes of acute ischemic stroke. Among the patients in the Fukuoka Stroke Registry, 1874 patients with first-ever acute ischemic stroke (within 24 hours of onset) who had been functionally independent before onset were prospectively enrolled in the present study. The poststroke BP levels were defined as the average values during the 48 hours after onset. The study outcomes were a good...
Source: Hypertension - December 11, 2013 Category: Cardiology Authors: Ishitsuka, K., Kamouchi, M., Hata, J., Fukuda, K., Matsuo, R., Kuroda, J., Ago, T., Kuwashiro, T., Sugimori, H., Nakane, H., Kitazono, T., on behalf of the FSR Investigators Tags: Stroke and Blood Pressure Source Type: research

Metformin-inclusive Therapy Reduces the Risk of Stroke in Patients with Diabetes: A 4-Year Follow-up Study
Metformin is a kind of oral hypoglycemic agents commonly prescribed to patients with diabetes mellitus. Although past studies had proven its protective effect on cardiovascular risk and related mortality, the evidence of metformin on stroke prevention was still insufficient and conflicting. Our study randomly selected 14,856 patients with diabetes from the database provided by the Taiwan National Health Research Institute, and 2 cohorts were formulated according to whether metformin was in the prescription record. All cases were followed up for 4 years to track their stroke incidence. As a result, 701 (17.5%) of 3999 diabe...
Source: Journal of Stroke and Cerebrovascular Diseases - October 11, 2013 Category: Neurology Authors: Yuan-Yang Cheng, Hsin-Bang Leu, Tzeng-Ji Chen, Chen-Ling Chen, Chia-Hua Kuo, Shin-Da Lee, Chung-Lan Kao Tags: Original Articles Source Type: research

A decade of racial and ethnic stroke disparities in the United States
Stroke is the fourth leading cause of death and the leading cause of long-term disability in the United States. Stroke incidence and prevalence is not uniform. It occurs more frequently in some geographical areas of the United States and the rates are higher in minority groups.1,2 Some proposed causes for these disparities include increased rate of vascular risk factors that disproportionally affect some minority groups, differential effect of hypertension on stroke risk across racial groups, lack of access to health care and other social determinants of health, suboptimal control of risk factors, and although lacking subs...
Source: Neurology - March 24, 2014 Category: Neurology Authors: Gutierrez, J., Williams, O. A. Tags: Other cerebrovascular disease/ Stroke, All Cerebrovascular disease/Stroke, Prevalence studies, Risk factors in epidemiology GLOBAL PERSPECTIVES Source Type: research