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Condition: Hypertension

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Total 16251 results found since Jan 2013.

Population-Based Study of Blood Biomarkers in Prediction of Subacute Recurrent Stroke Clinical Sciences
Conclusions— In the largest study to date, we found limited predictive use for early recurrent stroke for a panel of inflammatory, thrombotic, and cell damage biomarkers.
Source: Stroke - September 22, 2014 Category: Neurology Authors: Segal, H. C., Burgess, A. I., Poole, D. L., Mehta, Z., Silver, L. E., Rothwell, P. M. Tags: Other diagnostic testing, Risk Factors for Stroke, Coagulation and fibronolysis Clinical Sciences Source Type: research

Embolic Strokes of Undetermined Source in the Athens Stroke Registry: A Descriptive Analysis Clinical Sciences
Conclusions— About 10% of patients with first-ever ischemic stroke met criteria for ESUS; covert paroxysmal AF seems to be a frequent cause of ESUS.
Source: Stroke - December 22, 2014 Category: Neurology Authors: Ntaios, G., Papavasileiou, V., Milionis, H., Makaritsis, K., Manios, E., Spengos, K., Michel, P., Vemmos, K. Tags: Embolic stroke Clinical Sciences Source Type: research

Effects of Blood Pressure and Blood Pressure-Lowering Treatment During the First 24 Hours Among Patients in the Third International Stroke Trial of Thrombolytic Treatment for Acute Ischemic Stroke Clinical Sciences
Conclusions— Among patients with ischemic stroke who are candidates for thrombolytic treatment, high baseline blood pressure and a large pressure variability during the first 24 hours may be associated with a poor prognosis, whereas a large reduction in blood pressure and the use of blood pressure–lowering treatment during the first 24 hours may be associated with a favorable prognosis. These data support the rationale for further trials of agents that lower blood pressure or reduce blood pressure variability in the acute phase of ischemic stroke. Clinical Trial Registration— URL: http://www.clinicaltria...
Source: Stroke - November 23, 2015 Category: Neurology Authors: Berge, E., Cohen, G., Lindley, R. I., Sandercock, P., Wardlaw, J. M., Sandset, E. C., Whiteley, W. Tags: Treatment, Cerebrovascular Disease/Stroke, Ischemic Stroke Clinical Sciences Source Type: research

Acute-Phase Blood Pressure Levels Correlate With a High Risk of Recurrent Strokes in Young-Onset Ischemic Stroke Clinical Sciences
Conclusions— In young ischemic stroke patients, high acute phase BP levels are independently associated with a high risk of recurrent strokes.
Source: Stroke - May 22, 2016 Category: Neurology Authors: Mustanoja, S., Putaala, J., Gordin, D., Tulkki, L., Aarnio, K., Pirinen, J., Surakka, I., Sinisalo, J., Lehto, M., Tatlisumak, T. Tags: Lifestyle, High Blood Pressure, Ischemic Stroke Clinical Sciences Source Type: research

Association Between Midlife Cardiorespiratory Fitness and Risk of Stroke: The Cooper Center Longitudinal Study Clinical Sciences
Conclusions— There is a strong, inverse association between midlife CRF and stroke risk in later life independent of baseline and antecedent burden of risk factors, such as hypertension, diabetes mellitus, and atrial fibrillation.
Source: Stroke - June 26, 2016 Category: Neurology Authors: Pandey, A., Patel, M. R., Willis, B., Gao, A., Leonard, D., Das, S. R., Defina, L., Berry, J. D. Tags: Epidemiology, Cerebrovascular Disease/Stroke Clinical Sciences Source Type: research

Infections and Risk of Peripartum Stroke During Delivery Admissions Clinical Sciences
Conclusions—Infections present on admission increased stroke risk during delivery admissions in women with and without hypertensive disorders of pregnancy. The results were driven by genitourinary infections and sepsis. Infections may be an underrecognized precipitant of peripartum stroke.
Source: Stroke - April 23, 2018 Category: Neurology Authors: Eliza C. Miller, Marisa Gallo, Erin R. Kulick, Alexander M. Friedman, Mitchell S.V. Elkind, Amelia K. Boehme Tags: Pregnancy, Risk Factors, Women, Cerebrovascular Disease/Stroke Original Contributions Source Type: research

Effects of Blood Pressure in the Early Phase of Ischemic Stroke and Stroke Subtype on Poststroke Cognitive Impairment Clinical Sciences
This study was to investigate the impact of BP levels in the early phase of ischemic stroke and stroke subtype on PSCI.Methods—Seven hundred and ninety-six patients with acute ischemic stroke were included. Cognitive function was assessed after stroke onset using the Montreal Cognitive Assessment. Patients were divided into quintiles according to systolic BP and diastolic BP levels in the early phase. Subtype analyses were according to Trial of ORG 10172 in Acute Stroke Treatment classification (infarct cause) and Oxfordshire Community Stroke Project classification (infarct location).Results—After adjusting for multipl...
Source: Stroke - June 25, 2018 Category: Neurology Authors: Mingli He, Jin’e Wang, Na Liu, Xiao Xiao, Shan Geng, Pin Meng, Niu Ji, Yong’an Sun, Bingchao Xu, Yingda Xu, Xinyu Zhou, Guanghui Zhang, Xiaobing He, Zenglin Cai, Zaipo Li, Bei Wang, Bei Xu, Rutai Hui, Yibo Wang Tags: High Blood Pressure, Cognitive Impairment, Ischemic Stroke Original Contributions Source Type: research

Diabetes and stroke prevention: a review.
Authors: Hewitt J, Castilla Guerra L, Fernández-Moreno Mdel C, Sierra C Abstract Stroke and diabetes mellitus are two separate conditions which share multiple common threads. Both are increasing in prevalence, both are diseases which affect blood vessels, and both are associated with other vascular risk factors, such as hypertension and dyslipidemia. Abnormal glucose regulation, of which diabetes is one manifestation, is seen in up to two-thirds of people suffering from an acute stroke. Surprisingly, aggressive management of glucose after an acute stroke has not been shown to improve outcome or reduce the incidenc...
Source: Stroke Research and Treatment - December 2, 2014 Category: Neurology Tags: Stroke Res Treat Source Type: research

Prevalence of Stroke and Its Risk Factors in Urban Sri Lanka: Population-Based Study Brief Reports
Conclusions— Age-adjusted stroke prevalence in urban Sri Lanka lies between high-income and low-/middle-income countries. The prevalence of stroke and its risk factors were higher among men.
Source: Stroke - September 28, 2015 Category: Neurology Authors: Chang, T., Gajasinghe, S., Arambepola, C. Tags: Cerebrovascular disease/stroke, Acute Cerebral Hemorrhage, Acute Cerebral Infarction Brief Reports Source Type: research

Recanalization Modulates Association Between Blood Pressure and Functional Outcome in Acute Ischemic Stroke Clinical Sciences
Conclusions— Systemic BP in the first 24 hours after ischemic stroke influences 3-month clinical outcome. This association is dependent on the revascularization status.
Source: Stroke - May 22, 2016 Category: Neurology Authors: Martins, A. I., Sargento-Freitas, J., Silva, F., Jesus-Ribeiro, J., Correia, I., Gomes, J. P., Aguiar-Goncalves, M., Cardoso, L., Machado, C., Rodrigues, B., Santo, G. C., Cunha, L. Tags: High Blood Pressure, Hypertension, Cerebrovascular Procedures, Ischemic Stroke Clinical Sciences Source Type: research

Sustained Neurological Recovery After Stroke in Aged Rats Treated With a Novel Prostacyclin Analog Basic Sciences
Conclusions—Our data suggest that targeting the IP receptor with MRE-269 is a novel strategy to reduce cerebral ischemia injury and promote long-term neurological recovery in ischemic stroke.
Source: Stroke - June 26, 2017 Category: Neurology Authors: Changjun Yang, Kelly M. DeMars, Jon C. Alexander, Marcelo Febo, Eduardo Candelario-Jalil Tags: Cerebrovascular Disease/Stroke, Ischemic Stroke, Neuroprotectants Original Contributions Source Type: research

Increased Risk of Pregnancy Complications After Stroke Clinical Sciences
Background and Purpose—The study goal was to investigate the prevalence of pregnancy complications and pregnancy loss in women before, during, and after young ischemic stroke/transient ischemic attack.Methods—In the FUTURE study (Follow-Up of Transient Ischemic Attack and Stroke Patients and Unelucidated Risk Factor Evaluation), a prospective young stroke study, we assessed the occurrence of pregnancy, miscarriages, and pregnancy complications in 223 women aged 18 to 50 years with a first-ever ischemic stroke/transient ischemic attack. Pregnancy complications (gestational hypertension, diabetes mellitus, preeclampsia, ...
Source: Stroke - March 26, 2018 Category: Neurology Authors: Mayte E. van Alebeek, Myrthe de Vrijer, Renate M. Arntz, Noortje A.M.M. Maaijwee, Nathalie E. Synhaeve, Hennie Schoonderwaldt, Maureen J. van der Vlugt, Ewoud J. van Dijk, Roel de Heus, Loes C.A. Rutten-Jacobs, Frank-Erik de Leeuw Tags: Cerebrovascular Disease/Stroke, Ischemic Stroke Original Contributions Source Type: research

Clinical Utility of Electronic Alberta Stroke Program Early Computed Tomography Score Software in the ENCHANTED Trial Database Clinical Sciences
Background and Purpose—Clinical utility of electronic Alberta Stroke Program Early CT Score (e-ASPECTS), an automated system for quantifying signs of infarction, was evaluated in a large database of thrombolyzed patients with acute ischemic stroke.Methods—All baseline noncontrast computed tomographic scans of patients with anterior circulation acute ischemic stroke who participated in the alteplase dose arm of the randomized controlled trial ENCHANTED (Enhanced Control of Hypertension and Thrombolysis Stroke Study) were reviewed; poor quality and large (>6 mm) slice thickness were excluded. Included scans had e-ASPECTS...
Source: Stroke - May 25, 2018 Category: Neurology Authors: Simon Nagel, Xia Wang, Cheryl Carcel, Thompson Robinson, Richard I. Lindley, John Chalmers, Craig S. Anderson Tags: Cerebrovascular Disease/Stroke, Ischemic Stroke Original Contributions Source Type: research

Balloon Guide Catheter Improves Revascularization and Clinical Outcomes With the Solitaire Device: Analysis of the North American Solitaire Acute Stroke Registry Clinical Sciences
Conclusions— Use of a BGC with the Solitaire Flow Restoration device resulted in superior revascularization results, faster procedure times, decreased need for adjunctive therapy, and improved clinical outcome.
Source: Stroke - December 23, 2013 Category: Neurology Authors: Nguyen, T. N., Malisch, T., Castonguay, A. C., Gupta, R., Sun, C.-H. J., Martin, C. O., Holloway, W. E., Mueller-Kronast, N., English, J. D., Linfante, I., Dabus, G., Marden, F. A., Bozorgchami, H., Xavier, A., Rai, A. T., Froehler, M. T., Badruddin, A., Tags: Emergency treatment of Stroke, Other Stroke Treatment - Medical, Other Stroke Treatment - Surgical Clinical Sciences Source Type: research

Elevated Levels of Hemoglobin A1c Are Associated With Cerebral White Matter Disease in Patients With Stroke Clinical Sciences
Conclusions— Among known risk factors, higher levels of HbA1c were associated with cerebral WMD in stroke patients. This may suggest that chronic disturbance of glycemia measured by HbA1c plays a role in the pathophysiology of WMD. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT00715533.
Source: Stroke - March 24, 2014 Category: Neurology Authors: Rozanski, M., Richter, T. B., Grittner, U., Endres, M., Fiebach, J. B., Jungehulsing, G. J. Tags: Cerebrovascular disease/stroke, Glucose intolerance, CT and MRI Clinical Sciences Source Type: research