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Condition: Hypertension

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Total 16251 results found since Jan 2013.

Short-Term Blood Pressure Variability in Acute Stroke: Post Hoc Analysis of the Controlling Hypertension and Hypotension Immediately Post Stroke and Continue or Stop Post-Stroke Antihypertensives Collaborative Study Trials Clinical Sciences
Conclusions— When derived from casual cuff BP measures, short-term BPV is not a useful predictor of early (2 weeks) outcome after acute stroke. Differing methodology may account for the discordance with previous studies indicating long-term (casual BPV) and short-term (beat-to-beat BPV) prognostic value. Clinical Trial Registration— COSSACS was registered on the International Standard Randomised Controlled Trial Register; URL: http://www.isrctn.com. Unique identifier: ISRCTN89712435. CHHIPS was registered on the National Research Register; URL: http://public.ukcrn.org.uk. Unique identifier: N0484128008.
Source: Stroke - May 22, 2015 Category: Neurology Authors: Manning, L. S., Mistri, A. K., Potter, J., Rothwell, P. M., Robinson, T. G. Tags: Cerebrovascular disease/stroke, Clinical Studies, Acute Stroke Syndromes Clinical Sciences Source Type: research

Obesity Increases Risk of Ischemic Stroke in Young Adults Brief Reports
Conclusions— These results indicate that obesity is a risk factor for young onset ischemic stroke and suggest that this association may be partially mediated through hypertension, diabetes mellitus, or other variables associated with these conditions.
Source: Stroke - May 22, 2015 Category: Neurology Authors: Mitchell, A. B., Cole, J. W., McArdle, P. F., Cheng, Y.-C., Ryan, K. A., Sparks, M. J., Mitchell, B. D., Kittner, S. J. Tags: Risk Factors for Stroke Brief Reports Source Type: research

Efficacy and Safety of Platelet Glycoprotein Receptor Blockade in Aged and Comorbid Mice With Acute Experimental Stroke Basic Sciences
Conclusions— Inhibition of early steps of thrombus formation protects adult and comorbid mice from ischemic stroke. The use of clinically meaningful mouse strains might improve the translation of preclinical stroke research to the clinic.
Source: Stroke - November 23, 2015 Category: Neurology Authors: Kraft, P., Schuhmann, M. K., Fluri, F., Lorenz, K., Zernecke, A., Stoll, G., Nieswandt, B., Kleinschnitz, C. Tags: Animal Models of Human Disease, Hypertension, Treatment, Ischemic Stroke, Atherosclerosis Basic Sciences Source Type: research

Short Leukocyte Telomere Length Is Associated With Cardioembolic Stroke Risk in Patients With Atrial Fibrillation Brief Reports
Conclusions— Telomere shortening is associated with cardioembolic stroke risk in patients with AF. Prospective studies are encouraged to establish the value of LTL to improve prediction tools to categorize cardioembolic stroke risk in AF.
Source: Stroke - February 22, 2016 Category: Neurology Authors: Allende, M., Molina, E., Gonzalez-Porras, J. R., Toledo, E., Lecumberri, R., Hermida, J. Tags: Atrial Fibrillation, Risk Factors, Genetics, Cerebrovascular Disease/Stroke, Ischemic Stroke Brief Reports Source Type: research

CHA2DS2-VASc Score (Congestive Heart Failure, Hypertension, Age >=75 Doubled, Diabetes Mellitus, Prior Stroke or Transient Ischemic Attack Doubled, Vascular Disease, Age 65-74, Female) for Stroke in Asian Patients With Atrial Fibrillation Clinical Sciences
Background and Purpose—The CHA2DS2-VASc stroke score (congestive heart failure, hypertension, age ≥75 (doubled), diabetes mellitus, prior stroke or transient ischemic attack (doubled), vascular disease, age 65–74, female) is used in most guidelines for risk stratification in atrial fibrillation (AF), but most data for this score have been derived in Western populations. Ethnic differences in stroke risk may be present. Our objective was to investigate risk factors for stroke in AF and application of the CHA2DS2-VASc score in an Asian AF population from Korea.Methods—A total of 5855 oral anticoagulant–naive nonval...
Source: Stroke - May 22, 2017 Category: Neurology Authors: Tae-Hoon Kim, Pil-Sung Yang, Jae-Sun Uhm, Jong-Youn Kim, Hui-Nam Pak, Moon-Hyoung Lee, Boyoung Joung, Gregory Y.H. Lip Tags: Arrhythmias, Risk Factors, Ischemic Stroke Original Contributions Source Type: research

CHA2DS2-VASc Score for Identifying Truly Low-Risk Atrial Fibrillation for Stroke Clinical Sciences
Conclusions—The CHA2DS2-VASc score shows good performance in defining truly low-risk Asian patients with atrial fibrillation for stroke compared with CHADS2 and ATRIA scores.
Source: Stroke - October 23, 2017 Category: Neurology Authors: Tae-Hoon Kim, Pil-Sung Yang, Daehoon Kim, Hee Tae Yu, Jae-Sun Uhm, Jong-Youn Kim, Hui-Nam Pak, Moon-Hyoung Lee, Boyoung Joung, Gregory Y.H. Lip Tags: Atrial Fibrillation, Quality and Outcomes, Ischemic Stroke Original Contributions Source Type: research

Prognostic Significance of Blood Pressure Variability on Beat-to-Beat Monitoring After Transient Ischemic Attack and Stroke Clinical Sciences
Conclusions—Beat-to-beat BPV predicted recurrent stroke and cardiovascular events, independently of mean systolic BP and risk factors but short-term BPV on ambulatory BP monitoring did not. Beat-to-beat BPV may be a useful additional marker of cardiovascular risk.
Source: Stroke - December 22, 2017 Category: Neurology Authors: Alastair J.S. Webb, Sara Mazzucco, Linxin Li, Peter M. Rothwell Tags: Hypertension, Prognosis, Cerebrovascular Disease/Stroke Original Contributions Source Type: research

Effect of Smoking and Folate Levels on the Efficacy of Folic Acid Therapy in Prevention of Stroke in Hypertensive Men Clinical Sciences
Conclusions—Baseline folate levels and smoking status can interactively affect the risk of first stroke. Our data suggest that compared with never smokers, ever smokers may require a higher dosage of folic acid to achieve a greater beneficial effect on stroke. Our findings need to be confirmed by future randomized trials.Clinical Trial Registration—URL: https://www.clinicaltrials.gov. Unique identifier: NCT00794885.
Source: Stroke - December 22, 2017 Category: Neurology Authors: Ziyi Zhou, Jianping Li, Yaren Yu, Youbao Li, Yan Zhang, Lishun Liu, Yun Song, Min Zhao, Yu Wang, Genfu Tang, Mingli He, Xiping Xu, Yefeng Cai, Qiang Dong, Delu Yin, Xiao Huang, Xiaoshu Cheng, Binyan Wang, Fan Fan Hou, Xiaobin Wang, Xianhui Qin, Yong Huo Tags: Primary Prevention, Hypertension, Treatment, Cerebrovascular Disease/Stroke Original Contributions Source Type: research

Moderate-to-vigorous physical activity and the risk of stroke recurrence in patients with a history of minor ischemic stroke in Japan: a retrospective analysis.
CONCLUSIONS: Patients with a history of mild ischemic stroke had low MVPA and high VFL values, which together may be a risk factor for RIS. PMID: 30207894 [PubMed - as supplied by publisher]
Source: Topics in Stroke Rehabilitation - September 12, 2018 Category: Neurology Authors: Ushio M, Kanaoka M, Kinoshita Y, Maeno S, Fujita K Tags: Top Stroke Rehabil Source Type: research

All-cause mortality for cohabiting spouses of stroke survivors: Evidence from Swedish national registries.
CONCLUSION: Spouses of stroke survivors have higher mortality rates than a matched reference population that persist for a minimum of 5 years. Policy-makers should acknowledge and address the health status of spouses when evaluating and planning the health and social care of stroke survivors. PMID: 33048024 [PubMed - as supplied by publisher]
Source: Topics in Stroke Rehabilitation - October 13, 2020 Category: Neurology Authors: Persson J, Sheehan OC, Strömberg U, Roth DL Tags: Top Stroke Rehabil Source Type: research

Genome-Wide Analysis of Blood Pressure Variability and Ischemic Stroke Clinical Sciences
Conclusions— We identified a cluster of single nucleotide polymorphisms at the NLGN1 locus showing significant association with BP variability. Follow-up analyses did not support an association with risk of ischemic stroke and its subtypes.
Source: Stroke - September 23, 2013 Category: Neurology Authors: Yadav, S., Cotlarciuc, I., Munroe, P. B., Khan, M. S., Nalls, M. A., Bevan, S., Cheng, Y.-C., Chen, W.-M., Malik, R., McCarthy, N. S., Holliday, E. G., Speed, D., Hasan, N., Pucek, M., Rinne, P. E., Sever, P., Stanton, A., Shields, D. C., Maguire, J. M., Tags: Other hypertension, Genetics of Stroke, Risk Factors for Stroke Clinical Sciences Source Type: research

Low Glomerular Filtration Rate, Recurrent Stroke Risk, and Effect of Renin-Angiotensin System Modulation Brief Reports
Conclusions— Low eGFR is independently associated with a higher risk of recurrent stroke, but short-term add-on telmisartan therapy does not seem to mitigate this risk. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT00153062.
Source: Stroke - October 21, 2013 Category: Neurology Authors: Ovbiagele, B., Bath, P. M., Cotton, D., Sha, N., Diener, H.-C., for the PRoFESS Investigators Tags: Secondary prevention, Pathophysiology, Risk Factors, Other diagnostic testing, Other Stroke Treatment - Medical Brief Reports Source Type: research

Thrombolysis in Patients With Mild Stroke: Results From the Austrian Stroke Unit Registry Clinical Sciences
Conclusions— In our study, intravenous rt-PA treatment was beneficial for patients with mild deficit. Given the observational nature of these results, our data might serve as an incentive for future randomized controlled trials to provide a basis for optimal patient selection.
Source: Stroke - February 24, 2014 Category: Neurology Authors: Greisenegger, S., Seyfang, L., Kiechl, S., Lang, W., Ferrari, J., on behalf of the Austrian Stroke Unit Registry Collaborators Tags: Acute Cerebral Infarction, Thrombolysis Clinical Sciences Source Type: research

Combined Effects of Socioeconomic Position, Smoking, and Hypertension on Risk of Ischemic and Hemorrhagic Stroke Clinical Sciences
Conclusions— Reducing smoking in those with low socioeconomic position and in those with hypertension could potentially reduce social inequality stroke incidence.
Source: Stroke - August 25, 2014 Category: Neurology Authors: Nordahl, H., Osler, M., Frederiksen, B. L., Andersen, I., Prescott, E., Overvad, K., Diderichsen, F., Rod, N. H. Tags: Behavioral/psychosocial - stroke, Cerebrovascular disease/stroke, Acute Cerebral Hemorrhage, Cerebral Aneurysm, AVM, & Subarachnoid hemorrhage, Epidemiology Clinical Sciences Source Type: research

Sickle Cell Trait and Incident Ischemic Stroke in the Atherosclerosis Risk in Communities Study Clinical Sciences
Conclusions— We observed an increased risk of ischemic stroke in blacks with SCT. Further investigation of the incidence and pathophysiology of stroke in patients with SCT is warranted.
Source: Stroke - September 22, 2014 Category: Neurology Authors: Caughey, M. C., Loehr, L. R., Key, N. S., Derebail, V. K., Gottesman, R. F., Kshirsagar, A. V., Grove, M. L., Heiss, G. Tags: Genetics of Stroke, Risk Factors for Stroke, Epidemiology Clinical Sciences Source Type: research