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Condition: Metabolic Syndrome
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Metabolic Syndrome Linked to Increased Risk for Stroke Recurrence
THURSDAY, July 29, 2021 -- Metabolic syndrome and some of its components are associated with stroke recurrence, according to a review published online July 28 in Neurology.
Fangfang Zhang, M.D., from Xianxiang Central Hospital in China, and...
Source: Drugs.com - Pharma News - July 29, 2021 Category: Pharmaceuticals Source Type: news
Fine-Mapping of the PLCL2 Gene Identifies Candidate Variants Associated With Ischaemic Stroke Risk in Metabolic Syndrome Patients
A genome-wide association study (GWAS) reported PLCL2 on chromosome 3p24. 3 (rs4618210:A>G) as a novel susceptibility locus for myocardial infarction in the Japanese population. As the most common pathological process, atherosclerosis leads to metabolic syndrome (MetS)-related ischaemic stroke (IS) and myocardial infarction. Hypothesizing that polymorphisms of the PLCL2 gene might be associated with the onset and prognosis of IS in MetS patients, we performed the following study in a Chinese Han population. A total of 709 cases (patients with MetS plus IS) and 711 controls (patients with MetS) were enrolled. A fine-mapp...
Source: Frontiers in Neurology - January 20, 2022 Category: Neurology Source Type: research
Fine-Mapping of the < em > PLCL2 < /em > Gene Identifies Candidate Variants Associated With Ischaemic Stroke Risk in Metabolic Syndrome Patients
Front Neurol. 2022 Jan 20;12:743169. doi: 10.3389/fneur.2021.743169. eCollection 2021.ABSTRACTA genome-wide association study (GWAS) reported PLCL2 on chromosome 3p24. 3 (rs4618210:A>G) as a novel susceptibility locus for myocardial infarction in the Japanese population. As the most common pathological process, atherosclerosis leads to metabolic syndrome (MetS)-related ischaemic stroke (IS) and myocardial infarction. Hypothesizing that polymorphisms of the PLCL2 gene might be associated with the onset and prognosis of IS in MetS patients, we performed the following study in a Chinese Han population. A total of 709 cases...
Source: Atherosclerosis - February 7, 2022 Category: Cardiology Authors: Xiaoya Huang Qiang Ye Yanlei Zhang Yanyan Chen Jia Li Jun Sun Zusen Ye Source Type: research
Acute glycemic variability and mortality of patients with acute stroke: a meta-analysis
Increased glucose fluctuation has been related to poor prognosis in patients with critical illnesses, while its prognostic role in patients with acute stroke remains unknown. The meta-analysis aimed to evaluat...
Source: Diabetology and Metabolic Syndrome - May 10, 2022 Category: Endocrinology Authors: Jinbo Lin, Chunsheng Cai, Yituan Xie and Li Yi Tags: Research Source Type: research
Effect of income level on stroke incidence and the mediated effect of simultaneous diagnosis of metabolic syndrome diseases; a nationwide cohort study in South Korea
This study aimed to determine whether a simultaneous diagnosis of main components of metabolic syndrome (MetS) (hypertension, diabetes mellitus, and dyslipidemia) plays a mediator between income level and stroke.
Source: Diabetology and Metabolic Syndrome - August 8, 2022 Category: Endocrinology Authors: Seungmin Jeong, Sung-il Cho and So Yeon Kong Tags: Research Source Type: research
Prognostic significance of diabetes and stress hyperglycemia in acute stroke patients
Hyperglycemic non-diabetic stroke patients have a worse prognosis than both normoglycemic and diabetic patients. Aim of this study was to assess whether hyperglycemia is an aggravating factor or just an epiphe...
Source: Diabetology and Metabolic Syndrome - August 29, 2022 Category: Endocrinology Authors: Antonio Muscari, Roberta Falcone, Guerino Recinella, Luca Faccioli, Paola Forti, Marco Pastore Trossello, Giovanni M. Puddu, Luca Spinardi and Marco Zoli Tags: Research Source Type: research
Association of metabolic syndrome with stroke, myocardial infarction, and other postoperative complications following carotid endarterectomy: A multicenter, retrospective cohort study
This study aimed to assess the impact of MetS on stroke, myocardial infarction (MI), mortality, and other complications following carotid endarterectomy (CEA).
Source: Annals of Vascular Surgery - May 23, 2023 Category: Surgery Authors: Usama Waqar, Muzamil Hamid Hussain, Warda Ahmed, Ahmad Areeb Chaudhry, Syed M.H. Ali Gardezi, Hasnain Zafar, Zia Ur Rehman Tags: Clinical Research Source Type: research
Association of triglyceride-glucose index with early neurological deterioration events in patients with acute ischemic stroke
The Triglyceride and Glucose (TyG) index has been found to have a strong correlation with the recurrence of acute ischemic stroke (AIS) and poor patient outcomes. Nevertheless, the relationship between the TyG...
Source: Diabetology and Metabolic Syndrome - May 30, 2023 Category: Endocrinology Authors: Jia Wang, Hao Tang, Xiaokun Wang, Jiarong Wu, Jiaqi Gao, Shuang Diao and Yun Wu Tags: Research Source Type: research
Association between metabolic syndrome and stroke: a population based cohort study
Both metabolic syndrome (MetS) and stroke are associated with increased risk of mortality. Here, we aimed to assess the prevalence of MetS among adults using three definitions (Adult Treatment Panel III (ATP-I...
Source: BMC Endocrine Disorders - June 6, 2023 Category: Endocrinology Authors: Amir Moghadam-Ahmadi, Narjes Soltani, Fatemeh Ayoobi, Zahra Jamali, Tabandeh Sadeghi, Nazanin Jalali, Alireza Vakilian, Mohammad Amin Lotfi and Parvin khalili Tags: Research Source Type: research
Triglyceride –glucose index and the risk of stroke in American adults: findings from the atherosclerosis risk in communities study
The associations between the triglyceride –glucose (TyG) index with subsequent stroke in American adults are unknown. The aim of this study was to determine the associations between baseline and trajectories of...
Source: Diabetology and Metabolic Syndrome - September 19, 2023 Category: Endocrinology Authors: Xinyi Wang, Qiyu Liu, Tongxin Wang, Wende Tian, Xuanye Chen, Jie Zhang, Qiuyi Li, Dan Ma, Lin Zhao, Zhuo Chen, Hao Xu and Keji Chen Tags: Research Source Type: research
PPAR agonists for the treatment of cardiovascular disease in patients with Diabetes
Conclusions: According to this study, Pioglitazone treatment in type 2 diabetes patients and hypersensitive Ischemic stroke patients is linked to minor ischemic stroke which is recurrent in Asian people. Pioglitazone and the telmisartan treatment have an increasing pleiotropic effect related to the higher PPAR- gamma effects. Further research needs to be conducted with the PPAR mechanism ' s details to confirm the PPAR effect on Ischemic stroke treatment. [Ethiop. J. Health Dev. 2021; 35(3): 249-257]Keywords: PPAR agonist, Dyslipidaemia, Thiazolidinediones, Type 2 diabetes, Pioglitazone, PPAR-alpha, PPAR-gamma, Insulin resistance, Alecardio.
Source: Ethiopian Journal of Health Development - November 25, 2021 Category: African Health Authors: Zheng Xia, Guo Lixia, Zhang Zhijun Source Type: research
Atrial Fibrillation and Injected Aripiprazole: A Case Report
Conclusion
In summary, although it is not possible to exclude confounding factors, the timing and dose-dependent effect of aripiprazole administration in our patient suggests an association between an initial intramuscular injection of long-acting aripiprazole and new onset of AF. This observation calls for clinical vigilance, not only in patients with additional risk factors for stroke but also in younger patients who might have predisposing factors for arrhythmias.
References
CPS (Canadian Pharmacists Association). Available at: http://www.e-therapeutics.ca. Accessed January 1, 2017.
Polcwiartek C, Sneider B, Graff C,...
Source: Innovations in Clinical Neuroscience - May 1, 2018 Category: Neuroscience Authors: ICNS Online Editor Tags: Case Report Current Issue adverse effects aripiprazole atrial fibrillation schizoaffective disorder Source Type: research
The potential role of insulin resistance in predicting outcome from intravenous thrombolytic therapy
ConclusionInsulin resistance and metabolic syndrome were associated with worse functional outcomes in non-diabetic stroke patients after receiving rt-PA.
Source: Acta Neurologica Belgica - August 20, 2022 Category: Neurology Source Type: research
Inflammatory and Metabolic Syndrome Biomarker Analysis of Vascular Outcomes in End-stage Renal Disease
Int J Angiol DOI: 10.1055/s-0036-1593409End-stage renal disease (ESRD) presents a complex syndrome in which inflammatory and metabolic processes contribute to disease progression and development of comorbid conditions. Over $1 trillion is spent globally on ESRD care.Plasma samples collected from 83 ESRD patients prior to hemodialysis were profiled for metabolic and inflammatory biomarker concentrations. Concentrations were compared between groups with and without history of stroke, acute coronary syndrome (ACS), congestive heart failure (CHF), and coronary artery disease (CAD).The 25 patients (30.1%) with history of stroke...
Source: International Journal of Angiology - October 4, 2016 Category: Cardiology Authors: Sweigert, Patrick J. Bansal, Vinod K. Hoppensteadt, Debra A. Saluk, Jennifer L. Syed, Daneyal A. Fareed, Jawed Tags: Original Article Source Type: research
