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Cancer: Head and Neck Cancer

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Total 116 results found since Jan 2013.

A nomogram for the prediction of cerebrovascular disease among patients with brain necrosis after radiotherapy for nasopharyngeal carcinoma
In various cancer populations, radiotherapy is associated with the development of vascular disease [1 –4]. Previous studies have established an increased incidence of carotid stenosis (CAS) and ischemic stroke in patients with head and neck cancer treated with radiotherapy [4,5]. A study of 6862 patients (age>65  years) showed that five-year incidence of cerebrovascular events was 19% in patients treated with radiotherapy alone compared with 14% in patients treated with surgery plus radiotherapy; the corresponding ten-year incidence were 34% and 25%, respectively [4].
Source: Radiotherapy and Oncology - December 21, 2018 Category: Radiology Authors: Jinhua Cai, Jinping Cheng, Honghong Li, Wei-Jye Lin, Yi Li, Xiaohuang Zhuo, Xiaolong Huang, Charles B. Simone, Wilbert S. Aronow, Edward L.W. Chow, Yamei Tang Tags: Original Article Source Type: research

Management of Radiation Induced Carotid Stenosis in Head and Neck Cancer.
CONCLUSION: RT in patients with HNSCC holds a significant risk factor of developing carotid artery stenosis and cerebrovascular events. Carotid stenting is preferable mode of treatment for radiation-induced stenosis. A screening program with doppler ultrasonography enables pre-stroke detection of carotid stenosis. PMID: 31146165 [PubMed - as supplied by publisher]
Source: Translational Oncology - May 26, 2019 Category: Cancer & Oncology Authors: Trojanowski P, Sojka M, Trojanowska A, Wolski A, Roman T, Jargiello T Tags: Transl Oncol Source Type: research

Tu1115 PERCUTANEOUS ENDOSCOPIC GASTROSTOMY (PEG) IS ASSOCIATED WITH BETTER OUTCOMES AS COMPARED TO INTERVENTIONAL RADIOLOGY (IR) GUIDED AND SURGICAL GASTROSTOMIES: INSIGHTS FROM THE NATIONWIDE INPATIENT SAMPLE
Gastrostomy is a commonly performed procedure for enteral feeding in patients with diverse conditions such as malnutrition, stroke, dementia, Parkinsonism and other neurodegenerative diseases as well as head and neck and upper gastrointestinal cancers. PEG is usually preferred but IR guided and surgical gastrostomies are often performed based on patient related factors and local practice preferences. The aim of our study was to review demographic and clinical characteristics of patients undergoing gastrostomies in the inpatient setting.
Source: Gastrointestinal Endoscopy - May 31, 2019 Category: Gastroenterology Authors: Ishani Shah, Abhishek Bhurwal, Harsh Mehta, Shruti Mony, Ananya Das Tags: Tuesday abstract Source Type: research

Saliva-omics in Plasma Cell Disorders-proof of concept and potential as a non-invasive tool for monitoring disease burden and MRD status.
Salivaomics has exciting potential for the diagnosis and monitoring of malignancy, evidence of which has been reported in oral cancer, head and neck malignancies and ovarian cancer. It has been observed that approximately 40% of cancer, stroke and cardiovascular disease biomarkers are present in whole saliva. Salivaomics has become an area of great interest in disease diagnosis over the last number of years, following the footsteps of the other "omics ” based diagnostic tools. Saliva is a fast, inexpensive and non-invasive method of sample collection therefore it might be considered as the biofluid of choice for the diag...
Source: Clinical Lymphoma, Myeloma and Leukemia - September 30, 2019 Category: Hematology Authors: Ciara Tierney, Despina Bazou, Giao Le, Paul Dowling, Peter O'Gorman Source Type: research

Impaired Movement Scaling and Reduced Synchrony with Vestibule Closure Characterize Swallowing in Severe Dysphagia
In conclusion, the central schema for swallowing patterning was di sturbed, impairing the integration of kinematic actions for airway protection in severe dysphagia, while laryngeal peak elevation velocity predicted penetration and aspiration on patient swallows.
Source: Dysphagia - October 18, 2019 Category: Speech-Language Pathology Source Type: research

Longitudinal atherosclerotic changes after radio(chemo)therapy of hypopharyngeal carcinoma
This study aimed at a closer characterization of this damage and its development in time with a longitudi...
Source: Radiation Oncology - May 7, 2020 Category: Cancer & Oncology Authors: Cristoforo Simonetto, Michael Mayinger, Thamer Ahmed, Kai Borm, Pavel Kundr át, Steffi Pigorsch, Jan Christian Kaiser and Stephanie E. Combs Tags: Research Source Type: research

Association Among Age-Related Tongue Muscle Abnormality, Tongue Pressure, and Presbyphagia: A 3D MRI Study
AbstractMuscle aging such as sarcopenia adversely affects motor activities. However, few studies have elucidated the aging physiological mechanism of tongue concerted with the changes muscle composition. The present study aimed to examine the tongue composition changes to detect the effect of tongue fat mass on tongue pressure and swallowing function with aging. Twenty community-dwelling elderly without head and neck cancer, stroke, or neuromuscular disease and 20 healthy young were included. Tongue volume, tongue fat mass, tongue lean muscle mass, and tongue fat percentage were evaluated with 3D magnetic resonance imaging...
Source: Dysphagia - August 1, 2020 Category: Speech-Language Pathology Source Type: research

Outcomes of Combined Antegrade –Retrograde Dilations for Radiation-Induced Esophageal Strictures in Head and Neck Cancer Patients
AbstractThe purpose of this study is to analyze outcomes of combined antegrade –retrograde dilations (CARD). This retrospective study was conducted on 14 patients with a history of head and neck cancer, treated with radiation therapy that was complicated by either complete or near-complete esophageal stenosis. All patients had minimal oral intake and depended on a gastrostom y tube for nutrition. Swallow function before and after CARD was assessed using the Functional Oral Intake Scale, originally developed for stroke patients and applied to head and neck cancer patients. Patients undergoing CARD demonstrated a quantifia...
Source: Dysphagia - January 2, 2021 Category: Speech-Language Pathology Source Type: research

Effects of Neck Radiation on Result of Doppler Sonography of Carotid Arteries in Head and Neck Cancer Patients
The aim of this study was to assess the effects of neck radiation on the results of Doppler sonography of carotid arteries in head and neck cancer patients.
Source: Journal of Stroke and Cerebrovascular Diseases - January 15, 2021 Category: Neurology Authors: Ali Akhavan, Maryam Farghadani, Hamid Emami, Zahra Naderi Beni, Afsaneh Naderi Beni Source Type: research

Prevention of depression in adults with long-term physical conditions
CONCLUSIONS: Based on evidence of very low certainty, our results may indicate the benefit of pharmacological interventions, during or directly after preventive treatment. Few trials examined short-term outcomes up to six months, nor the follow-up effects at six to 12 months, with studies suffering from great numbers of drop-outs and inconclusive results. Generalisation of results is limited as study populations and treatment regimes were very heterogeneous. Based on the results of this review, we conclude that for adults with long-term physical conditions, there is only very uncertain evidence regarding the implementation...
Source: Cochrane Database of Systematic Reviews - March 5, 2021 Category: General Medicine Authors: Hanna Kampling Harald Baumeister J ürgen Bengel Oskar Mittag Source Type: research

Preclinical Dysphagia in Community Dwelling Older Adults: What Should We Look For?
Conclusions Dysphagia in CDOA is complex and multidimensional. Clinicians working with older adults will benefit from considering elements described in this multidimensional framework to better understand the etiology of swallowing deficits and improve management. Supplemental Material https://doi.org/10.23641/asha.14150078.PMID:33684295 | DOI:10.1044/2020_AJSLP-20-00014
Source: American Journal of Speech-Language Pathology - March 8, 2021 Category: Speech-Language Pathology Authors: Aarthi Madhavan Source Type: research

White Paper by the European Society for Swallowing Disorders: Screening and Non-instrumental Assessment for Dysphagia in Adults
AbstractThis White Paper by the European Society for Swallowing Disorders (ESSD) reports on the current state of screening and non-instrumental assessment for dysphagia in adults. An overview is provided on the measures that are available, and how to select screening tools and assessments. Emphasis is placed on different types of screening, patient-reported measures, assessment of anatomy and physiology of the swallowing act, and clinical swallowing evaluation. Many screening and non-instrumental assessments are available for evaluating dysphagia in adults; however, their use may not be warranted due to poor diagnostic per...
Source: Dysphagia - March 31, 2021 Category: Speech-Language Pathology Source Type: research