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Nutrition: Zinc

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Total 98 results found since Jan 2013.

Differential associations of particle size ranges and constituents with stroke emergency-room visits in Shanghai, China
CONCLUSION: Ultra-fine particles and some PM2.5 constituents (i.e., carbonaceous fractions, inorganic ions and some elements) may be mainly responsible for the excess risk of stroke induced by PM2.5.PMID:35104777 | DOI:10.1016/j.ecoenv.2022.113237
Source: Ecotoxicology and Environmental Safety - February 1, 2022 Category: Environmental Health Authors: Yuhao Zhang Qinglin He Yaping Zhang Xiaowei Xue Haidong Kan Xin Wang Source Type: research

Serum/Plasma Zinc Is Apparently Increased in Ischemic Stroke: a Meta-analysis
Biol Trace Elem Res. 2021 Apr 6. doi: 10.1007/s12011-021-02703-4. Online ahead of print.ABSTRACTZinc (Zn) is found in many neuronal pathways in the brain and has implications for neuromodulation and cerebrovascular disease. However, the association between Zn levels and stroke risk remains controversial. Therefore, we conducted a meta-analysis to explore these relationships. A systematic literature search using PubMed, EMBASE database, and Google Scholar was performed for relevant articles from inception to August 2020. Standardized mean differences (SMDs) and 95% confidence intervals (CIs) were considered the effect sizes...
Source: Biological Trace Element Research - April 7, 2021 Category: Biology Authors: Mengyun Huang Lijun Zhu Yan Chen Yuelong Jin Zhengmei Fang Yingshui Yao Source Type: research

Zfp580 Regulates Paracrine and Endocrine Igf1 and Igfbp3 Differently in the Brain and Blood After a Murine Stroke
In conclusion, Zfp580 differentially controls paracrine and endocrine Igf1 and Igfbp3 after stroke. Inhibition of Zfp580 might be a new treatment target leading to increased activity of Igf1 to improve stroke outcome.
Source: Frontiers in Physiology - April 26, 2022 Category: Physiology Source Type: research

Predictive value of long noncoding RNA ZFAS1 in patients with ischemic stroke.
CONCLUSION: These results suggest that ZFAS1 might be used as a potential noninvasive biomarker for the diagnosis of LAA stroke. PMID: 30307773 [PubMed - as supplied by publisher]
Source: Clinical and Experimental Hypertension - October 11, 2018 Category: Cardiology Authors: Wang J, Ruan J, Zhu M, Yang J, Du S, Xu P, Zhang Z, Wang P, Yang W, Yu M Tags: Clin Exp Hypertens Source Type: research

Reduction of zinc accumulation in mitochondria contributes to decreased cerebral ischemic injury by normobaric hyperoxia treatment in an experimental stroke model.
In this study, we investigate whether NBO could regulate zinc accumulation in the penumbra and prevent mitochondrial damage in penumbral tissue using a transient cerebral ischemic rat model. Our results showed that NBO significantly reduced zinc staining positive cells and zinc-staining intensity in penumbral tissues, but not in the ischemic core. Moreover, ischemia-induced zinc accumulation in mitochondria, isolated from penumbral tissues, was greatly attenuated by NBO or a zinc specific chelator, N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine (TPEN). NBO or TPEN administration stabilized the mitochondrial membrane po...
Source: Experimental Neurology - April 16, 2015 Category: Neurology Authors: Dong W, Qi Z, Liang J, Shi W, Zhao Y, Luo Y, Ji X, Liu KJ Tags: Exp Neurol Source Type: research

Identifying potential therapeutic targets for ischemic stroke through immune infiltration analysis and construction of a programmed cell death ‑related ceRNA network
Exp Ther Med. 2022 Sep 21;24(5):680. doi: 10.3892/etm.2022.11616. eCollection 2022 Nov.ABSTRACTThe present study aimed to uncover the underlying mechanisms and potential intervention targets of ischemic stroke (IS). An immune cell infiltration analysis using CIBERSORT was performed on two stroke-related datasets from the Gene Expression Omnibus database to generate a competitive endogenous RNA (ceRNA) network. Gene Ontology (GO) functional annotation and Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses were used to predict potential biological functions of the network. Differentially expressed genes in the ceRNA net...
Source: Experimental and Therapeutic Medicine - October 3, 2022 Category: General Medicine Authors: Yiteng Cui Xin Zhou Pingping Meng Shanshan Dong Ziwei Wang Tongye Liu Xiaomin Liu Yunteng Cui Yuyang Wang Qiang Wang Source Type: research