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Total 296 results found since Jan 2013.

Exposure to water-accommodated fractions of two different crude oils alters morphology, cardiac function and swim bladder development in early-life stages of zebrafish.
Abstract The present study investigated the developmental toxicity of water-accommodated fractions (WAFs) of Oman crude oil (OCO) and Merey crude oil (MCO) on zebrafish (Danio rerio) in early-life stages (ELS). Based on total petroleum hydrocarbons (TPH), LC50 values manifested that OCO WAF was 1.2-fold more lethal to zebrafish embryos than MCO WAF. As for hatching rate, EC50 value for OCO WAF was 5.7-fold lower than that for MCO WAF. To evaluate the sublethal morphological effects, semi-quantitative extended general morphological score (GMS) and general teratogenic score (GTS) systems were adopted. The GMS and GT...
Source: Chemosphere - June 25, 2019 Category: Chemistry Authors: Li X, Xiong D, Ding G, Fan Y, Ma X, Wang C, Xiong Y, Jiang X Tags: Chemosphere Source Type: research

Heartburn Drugs May Lead To Allergies, Study Suggests
(CNN) — When heartburn or ulcer pain strikes, drugs can target stomach acid to calm bellies and offer relief. But a new study suggests the medications may come with a hive-inducing side effect: allergies. After analyzing health insurance data from more than 8 million people in Austria, researchers found that prescriptions of anti-allergy medications surged in those who were prescribed stomach acid inhibitors, a class of drugs that includes proton-pump inhibitors and H2 blockers. The findings, published Tuesday in the medical journal Nature Communications, suggest that disrupting the stomach’s delicate balance o...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - July 30, 2019 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health News Allergies CNN Heartburn Source Type: news

On the Association Between Sleep Quality and Arterial Stiffness: A Population Study in Community-Dwelling Older Adults Living in Rural Ecuador (The Atahualpa Project)
Conclusions:This study shows a significant independent association between the aortic PWV and poor sleep quality in older adults living in rural Ecuador. Results provide more insights into the relevance of the impact of sleep disorders on cardiovascular diseases.Clinical Trial Registration:The Atahualpa Project has been registered atClinicalTrials.gov. The identifier number is NCT01627600, and the date was: 10/02/2012.Citation:Del Brutto OH, Mera RM, Peñaherrera E, Costa AF, Peñaherrera R, Castillo PR. On the association between sleep quality and arterial stiffness: a population study in community-dwelling ol...
Source: Journal of Clinical Sleep Medicine : JCSM - August 14, 2019 Category: Sleep Medicine Source Type: research

Risks of ischaemic heart disease and stroke in meat eaters, fish eaters, and vegetarians over 18 years of follow-up: results from the prospective EPIC-Oxford study
Source: BMJ - September 5, 2019 Category: General Medicine Source Type: research

Study Reveals Mixed Effects on Health for Vegetarian Diet
FRIDAY, Sept. 6, 2019 -- Vegetarians and fish eaters have a lower risk for ischemic heart disease compared with meat eaters, and vegetarians have a higher risk for stroke, according to a study published online Sept. 4 in The BMJ. Tammy Y.N. Tong,...
Source: Drugs.com - Pharma News - September 6, 2019 Category: Pharmaceuticals Source Type: news

External validation of the Vascular Study Group of New England carotid endarterectomy risk predictive model using an independent U.S. national surgical database
Previously, we described a Vascular Study Group of New England (VSGNE) risk predictive model to predict composite adverse outcomes (postoperative death, stroke, myocardial infarction, or discharge to extended care facilities) after carotid endarterectomy (CEA). The goal of this study was to externally validate this model using an independent database.
Source: Journal of Vascular Surgery - October 28, 2019 Category: Surgery Authors: Mohammad H. Eslami, Zein Saadeddin, Alik Farber, Larry Fish, Efthymios D. Avgerinos, Michel S. Makaroun Source Type: research

Many take anticoagulants and OTC supplements, which poses risk
FINDINGSNearly 98% percent of people prescribed direct-acting oral anticoagulants such as apixaban also used  over-the-counter products. Of those, 33% took at least one such product that, in combination with the anticoagulants, could cause dangerous internal bleeding. People taking these medications largely lacked knowledge of some potentially serious interactions.BACKGROUNDDirect-acting oral anticoagulants are the drug of choice for stroke prevention in patients with atrial fibrillation, which occurs most frequently in older patients. Apixaban is one of the most frequently prescribed. However, most people prescribed apix...
Source: UCLA Newsroom: Health Sciences - October 31, 2019 Category: Universities & Medical Training Source Type: news

A novel cysteine-sparing G73A mutation of NOTCH3 in a Chinese CADASIL family
AbstractCerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is the most common monogenic disease leading to stroke and vascular dementia. CADASIL is an inherited small blood vessel disease caused by mutations in the gene encoding the neurogenic locus notch homolog protein 3 (NOTCH3). NOTCH3 is large type I membrane receptor mainly expressed in vascular smooth muscle cells and pericytes. Most identified mutations result in insert or deletion of a cysteine residue within the EGF-like repeats. To date, some cases with a cysteine-sparing mutant have been described. Genetic analy...
Source: Neurogenetics - November 12, 2019 Category: Genetics & Stem Cells Source Type: research

FDA Panel: Expand Use of Fish Oil Drug Vascepa
FRIDAY, Nov. 15, 2019 -- Approved use of the prescription-strength fish oil drug Vascepa should be widened to include more patients at risk for heart attack and stroke, a U.S. Food and Drug Administration advisory panel recommended Thursday. Vascepa...
Source: Drugs.com - Pharma News - November 15, 2019 Category: Pharmaceuticals Source Type: news

Hypoxic Acclimation Negatively Impacts the Contractility of Steelhead Trout (Oncorhynchus mykiss) Spongy Myocardium.
Abstract Cardiac stroke volume (SV) is compromised in Atlantic cod and rainbow trout following acclimation to hypoxia (i.e., 40% air saturation; ~ 8 kPa O2) at 10-12oC, and this is not due to changes in heart morphometrics or maximum achievable in vitro end-diastolic volume. To examine if this diminished SVmay be related to compromised myocardial contractility, we used the work loop method to measure work and power in spongy myocardial strips from normoxia- and hypoxia-acclimated steelhead trout when exposed to decreasing PO2levels (21 to 1.5 kPa) at several frequencies (30 - 90 contractions min-1) at 14oC (their ...
Source: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology - November 19, 2019 Category: Physiology Authors: Carnevale C, Roberts JC, Syme DA, Gamperl AK Tags: Am J Physiol Regul Integr Comp Physiol Source Type: research

What ’s the Big Deal about Data in Medtech?
Discussion, “Top 5 Things You Need to Know about the Implantable Internet of Things." Brian Chapman, partner and leader of ZS’s medtech practice of ZS, attributes today’s focus on data to the intersection of two important things: "A general recognition that understanding more and connecting actions with outcomes will provide feedback and understanding that will drive standards of care. This is not new, but as capabilities rise in data collection, aggregation, and synthesize rise, and coupled with machine learning, the promise of data in healthcare is becoming even more ...
Source: MDDI - December 20, 2019 Category: Medical Devices Authors: Daphne Allen Tags: Digital Health Source Type: news

Critical Differences Between Dietary Supplement and Prescription Omega-3 Fatty Acids: A Narrative Review
ConclusionConsumers and health care providers need to recognize critical differences between Rx and OM-3 dietary supplements to ensure appropriate use of each OM-3 product.
Source: Advances in Therapy - January 8, 2020 Category: Drugs & Pharmacology Source Type: research

Using olive oil instead of these foods could add years to the life of your heart, study says
The health benefits of the Mediterranean diet are renowned: Lots and lots of veggies, fruit, fish and olive oil have been shown to strengthen bones, improve brain health and reduce the risk for some cancers, diabetes, high cholesterol, heart disease and stroke.
Source: CNN.com - Health - March 6, 2020 Category: Consumer Health News Source Type: news

Benefits of Fish Oil Resurface, but Do They Hold Water? Benefits of Fish Oil Resurface, but Do They Hold Water?
Habitual fish oil consumption is linked to a lower risk for all-cause and CVD mortality, stroke, and MI, results of a large observational study suggest. One expert is ' skeptical that the results are real. 'Medscape Medical News
Source: Medscape Cardiology Headlines - March 12, 2020 Category: Cardiology Tags: Neurology & Neurosurgery News Source Type: news

Food rich in vitamin D such as cheese and oily fish is good for the heart, research shows
Lovers of cheese, eggs and oily fish are in luck, after Scientists discovered that the foods may protect against a heart attack or stroke, with the benefits being much more marked in men than women.
Source: the Mail online | Health - April 8, 2020 Category: Consumer Health News Source Type: news