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Source: Atherosclerosis
Nutrition: Diets
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Total 102 results found since Jan 2013.
Crosstalk between neurological, cardiovascular, and lifestyle disorders: insulin and lipoproteins in the lead role
Pharmacol Rep. 2022 Sep 23. doi: 10.1007/s43440-022-00417-5. Online ahead of print.ABSTRACTInsulin resistance and impaired lipoprotein metabolism contribute to a plethora of metabolic and cardiovascular disorders. These alterations have been extensively linked with poor lifestyle choices, such as consumption of a high-fat diet, smoking, stress, and a redundant lifestyle. Moreover, these are also known to increase the co-morbidity of diseases like Type 2 diabetes mellitus and atherosclerosis. Under normal physiological conditions, insulin and lipoproteins exert a neuroprotective role in the central nervous system. However, ...
Source: Atherosclerosis - September 23, 2022 Category: Cardiology Authors: Richa Tyagi Bhupesh Vaidya Shyam Sunder Sharma Source Type: research
Guanmaitong Granule Attenuates Atherosclerosis by Inhibiting Inflammatory Immune Response in ApoE < sup > -/- < /sup > Mice Fed High-Fat Diet
CONCLUSION: Radix notoginseng, Radix salviae liguliobae, and Radix astragali are the main ingredients of GMTG for treating AS. Further, GMTG could regulate the level of serum lipids and inhibit inflammatory immune response, which resulted in anti-AS effects such as plaque stabilization, reduction of plaque burden, and plaque remodeling. GMTG is a promising multi-target treatment for AS.PMID:36148321 | PMC:PMC9489104 | DOI:10.2147/DDDT.S372143
Source: Atherosclerosis - September 23, 2022 Category: Cardiology Authors: Mengqi Yang Huachen Jiao Yan Li Lei Zhang Juan Zhang Xia Zhong Yitao Xue Source Type: research
Gut microbiota is a potential goalkeeper of dyslipidemia
Front Endocrinol (Lausanne). 2022 Sep 13;13:950826. doi: 10.3389/fendo.2022.950826. eCollection 2022.ABSTRACTDyslipidemia, as a common metabolic disease, could cause atherosclerosis, coronary heart disease, stroke and other cardio-cerebrovascular diseases. It is mainly caused by the interaction of genetic and environmental factors and its incidence has increased for several years. A large number of studies have shown that gut microbiota disorder is related to the development of dyslipidemia closely. Especially its metabolites such as short-chain fatty acids, bile acids and trimethylamine N-oxide affect dyslipidemia by regu...
Source: Atherosclerosis - September 30, 2022 Category: Cardiology Authors: Lirong Lei Ning Zhao Lei Zhang Jiamei Chen Xiaomin Liu Shenghua Piao Source Type: research
Mediterranean Diet and Its Association with Cardiovascular Disease Risk Factors: A Scoping Review
Int J Environ Res Public Health. 2022 Oct 6;19(19):12762. doi: 10.3390/ijerph191912762.ABSTRACTAtherosclerosis is the underlying cause of cardiovascular diseases (CVD) and is interrelated to stroke, heart attack, and heart failure. The Mediterranean Diet (MedDiet) has been closely associated with reduced CVD morbidity and mortality, but research is not well explored for this relationship in individuals with diabetes (who experience greater CVD morbidity and mortality than individuals without diabetes). The aim of this review was to explore the literature related to the MedDiet and atherosclerosis and associated risk factor...
Source: Atherosclerosis - October 14, 2022 Category: Cardiology Authors: Leigh Ann Richardson Kenneth Izuora Arpita Basu Source Type: research
Pristane attenuates atherosclerosis in Apoe < sup > -/- < /sup > mice via IL-4-secreting regulatory plasma cell-mediated M2 macrophage polarization
Biomed Pharmacother. 2022 Nov;155:113750. doi: 10.1016/j.biopha.2022.113750. Epub 2022 Sep 29.ABSTRACTAtherosclerosis, an inflammatory progressive vascular disease, causes heart disease and stroke worldwide. B cells with immune suppressive functions have been implicated in autoimmune, inflammatory, and cardiovascular diseases. However, the precise role of regulatory B cells and the interaction with macrophages in atherosclerosis remains undefined. In our study, eight-week-old female apolipoprotein E null (Apoe-/-) mice were treated with a single dose of vehicle or pristane and then placed on an atherogenic diet for 12 week...
Source: Atherosclerosis - October 22, 2022 Category: Cardiology Authors: Yimin Huang Kongyang Ma Rencai Qin Yaxiong Fang Jingquan Zhou Xiaoyan Dai Source Type: research
Influence of Management of Intensive Weight, Blood Pressure, and Lipids on Disease Severity in Patients with Carotid Atherosclerosis
CONCLUSIONS: A program for management of body weight, blood pressure, and blood lipids can effectively control the severity of carotid atherosclerosis, can prevent the disease's progression, and can be promoted as a clinical application.PMID:36455146
Source: Atherosclerosis - December 1, 2022 Category: Cardiology Authors: Yongjian Liu Xiaojing Yan Jin Zhou Litao Chen Zhixing Du Jianmin Pang Liya Jiao Dan Li Yongmin Deng Source Type: research
Fecal level of butyric acid, a microbiome-derived metabolite, is increased in patients with severe carotid atherosclerosis
Sci Rep. 2022 Dec 26;12(1):22378. doi: 10.1038/s41598-022-26759-x.ABSTRACTThe short-chain fatty acid (SCFA) butyric acid maintains a healthy gut barrier and vascular endothelium. We aimed to investigate the association between fecal butyric acid, carotid atherosclerosis and risk factors for ischemic stroke. Patients with severe carotid atherosclerosis (i.e. ≥ 50% stenosis) (n = 43) were compared with healthy controls (n = 38). We analyzed fecal SCFAs by gas chromatography, microbiota composition by 16S rRNA sequencing, markers of gut barrier damage and inflammasome activation by immunoassay, and plasma SCFAs by ultra-hig...
Source: Atherosclerosis - December 26, 2022 Category: Cardiology Authors: Kristine St ø J ørgen Valeur Thor Ueland Gunn Helen Malmstr øm Vigdis Bjerkeli Marius Tr øseid Johannes R Hov Kristian Holm Beate Vestad Bente Halvorsen Mona Skjelland Karolina R Skagen Source Type: research
Intake of marine and plant-derived n-3 fatty acids and development of atherosclerotic cardiovascular disease in the Danish Diet, Cancer and Health cohort
CONCLUSIONS: A high intake of marine n-3 PUFA was associated with a lower risk of total ASCVD and acute major ischemic events, whereas no association could be demonstrated for the plant-derived ALA.PMID:36592188 | DOI:10.1007/s00394-022-03081-w
Source: Atherosclerosis - January 2, 2023 Category: Cardiology Authors: Christian S Bork S øren Lundbye-Christensen Stine K Ven ø Anne N Lasota Anne Tj ønneland Erik B Schmidt Kim Overvad Source Type: research
Microarray Expression Profile of Myricetin-Treated THP-1 Macrophages Exhibits Alterations in Atherosclerosis-Related Regulator Molecules and LXR/RXR Pathway
Int J Mol Sci. 2022 Dec 23;24(1):278. doi: 10.3390/ijms24010278.ABSTRACTAtherosclerosis is a chronic inflammation characterized by macrophage infiltration, lipid deposition, and arterial wall thickening. Prevention of atherosclerosis by nutraceuticals is gaining attention. Myricetin, a dietary flavonol, is claimed to possess anti-atherosclerosis properties. We studied myricetin's effect on the atherosclerosis-associated molecular mechanism. Cytotoxicity and proliferation testing to check the viability of myricetin-treated THP-1 macrophages and monocyte migration study in the presence and absence of myricetin was performed....
Source: Atherosclerosis - January 8, 2023 Category: Cardiology Authors: Etimad Huwait Rehab Almassabi Sanaa Almowallad Salma Saddeek Sajjad Karim Gauthaman Kalamegam Zeenat Mirza Source Type: research
Pharmacological and Molecular Insight on the Cardioprotective Role of Apigenin
Nutrients. 2023 Jan 12;15(2):385. doi: 10.3390/nu15020385.ABSTRACTApigenin is a naturally occurring dietary flavonoid found abundantly in fruits and vegetables. It possesses a wide range of biological properties that exert antioxidant, anti-inflammatory, anticancer, and antibacterial effects. These effects have been reported to be beneficial in the treatment of atherosclerosis, stroke, hypertension, ischemia/reperfusion-induced myocardial injury, and diabetic cardiomyopathy, and provide protection against drug-induced cardiotoxicity. These potential therapeutic effects advocate the exploration of the cardioprotective actio...
Source: Atherosclerosis - January 21, 2023 Category: Cardiology Authors: Shilu Deepa Thomas Niraj Kumar Jha Saurabh Kumar Jha Bassem Sadek Shreesh Ojha Source Type: research
Association between dietary inflammatory index and atherosclerosis cardiovascular disease in U.S. adults
CONCLUSION: Our study revealed a positive and non-linearly association between DII and ASCVD in U.S. adults. This relationship was more pronounced in females. The findings provide a reference for future research and diet recommendations.PMID:36687707 | PMC:PMC9849765 | DOI:10.3389/fnut.2022.1044329
Source: Atherosclerosis - January 23, 2023 Category: Cardiology Authors: Jie Zhang Jundi Jia Runmin Lai Xinyi Wang Xuanye Chen Wende Tian Qiyu Liu Jingen Li Jianqing Ju Hao Xu Source Type: research
Mechanism of Tao Hong Decoction in the treatment of atherosclerosis based on network pharmacology and experimental validation
CONCLUSION: THD plays a vital role in treating AS with multiple targets and pathways. Angiogenesis regulation, oxidative stress regulation, and immunity regulation consist of the crucial regulation cores in the mechanism. This study identified essential genes and pathways associated with the prognosis and pathogenesis of AS from new insights, demonstrating a feasible method for researching THD's chemical basis and pharmacology.PMID:36776258 | PMC:PMC9909180 | DOI:10.3389/fcvm.2023.1111475
Source: Atherosclerosis - February 13, 2023 Category: Cardiology Authors: SiJin Li Ping Liu Xiaoteng Feng Min Du Yifan Zhang YiRu Wang JiaRou Wang Source Type: research
