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How To Avoid China ’ s Medicine Monopoly
I want to share a shocking statistic with you…
Around 80% of all the pharmaceuticals sold in America — both prescription and over-the-counter — are manufactured in China.
I’m talking about drugs for Parkinson’s and Alzheimer’s, blood pressure and blood thinners, diuretics, aspirin, antibiotics, and a big chunk of the world’s insulin and diabetes drugs — just to name a few.1
We don’t even make penicillin anymore. The last penicillin plant in the U.S. closed its doors in 2004.
Americans who rely on medicine are now almost entirely at the mercy of a country whose relations with the U.S. have become more ...
Source: Al Sears, MD Natural Remedies - September 19, 2023 Category: Complementary Medicine Authors: Jacob Tags: Health Source Type: news
Association of Coronary Artery Calcium Detected by Routine Ungated CT Imaging With Cardiovascular Outcomes
CONCLUSIONS: Incidental CAC ≥100 was associated with an increased risk of all-cause death and adverse cardiovascular outcomes, beyond traditional risk factors. DL-CAC from routine non-ECG-gated CTs identifies patients at increased cardiovascular risk and holds promise as a tool for opportunistic screening to facilitate earlier intervention.PMID:37704309 | DOI:10.1016/j.jacc.2023.06.040
Source: Atherosclerosis - September 13, 2023 Category: Cardiology Authors: Allison W Peng Ramzi Dudum Sneha S Jain David J Maron Bhavik N Patel Nishith Khandwala David Eng Akshay S Chaudhari Alexander T Sandhu Fatima Rodriguez Source Type: research
Coronary artery disease grading by cardiac CT for predicting outcome in patients with stable angina
CONCLUSION: In patients referred for invasive angiography, a history of CHD was the strongest predictor of MACE. In patients without history of CHD, a coronary calcium score yielded at least equal risk stratification vs. more complex CHD grading.PMID:37541910 | DOI:10.1016/j.jcct.2023.07.004
Source: Atherosclerosis - August 4, 2023 Category: Cardiology Authors: Christian U Oeing Matthew B Matheson Mohammad R Ostovaneh Carlos E Rochitte Marcus Y Chen Burkert Pieske Klaus F Kofoed Joanne D Schuijf Hiroyuki Niinuma Marc Dewey Marcelo F di Carli Christopher Cox Jo ão A C Lima Armin Arbab-Zadeh Source Type: research
AI-Guided Quantitative Plaque Staging Predicts Long-Term Cardiovascular Outcomes in Patients at Risk for Atherosclerotic CVD
CONCLUSIONS: Through 10-year follow-up, AI-QCT plaque staging showed important prognostic value for MACE and showed additional discriminatory value over clinical risk factors, CACS, and manual guideline-recommended CCTA assessment.PMID:37480907 | DOI:10.1016/j.jcmg.2023.05.020
Source: Atherosclerosis - July 22, 2023 Category: Cardiology Authors: Nick S Nurmohamed Michiel J Bom Ruurt A Jukema Robin J de Groot Roel S Driessen Pepijn A van Diemen Ruben W de Winter Emilie L Gaillard Ralf W Sprengers Erik S G Stroes James K Min James P Earls Rhanderson Cardoso Ron Blankstein Ibrahim Danad Andrew D Cho Source Type: research
Atherosclerosis on CT coronary angiography and risk of long-term cardiovascular events post liver transplantation
CONCLUSION: The standardized CAD-RADS classification on CTCA predicted the occurrence of cardiovascular outcomes following LT, with a potential to increase utilization of preventive cardiovascular therapies.PMID:37432891 | DOI:10.1097/LVT.0000000000000215
Source: Atherosclerosis - July 11, 2023 Category: Cardiology Authors: Thalys Sampaio Rodrigues Anoop N Koshy Paul J Gow Laurence Weinberg Benjamin Cailes Adam Testro Gerard Smith Han S Lim Andrew W Teh Ruth P Lim Omar Farouque Source Type: research
Effect of Nicorandil, Diltiazem, or Isosorbide Mononitrate for Oral Antispastic Therapy After Coronary Artery Bypass Grafting Using Radial Artery Grafts —A Pilot Randomized Controlled Trial (ASRAB-Pilot): Rationale and Study Protocol
ConclusionThis pilot trial will compare the preliminary effects of nicorandil, diltiazem, and isosorbide mononitrate on angiographic and clinical outcomes in patients who have undergone RA-CABG. Recruitment began in June 2020, and the estimated primary completion date is early 2023. Results of this study will provide much needed information for design of large confirmatory trials on the effectiveness of oral antispastic medications after RA-CABG.
Source: Advances in Therapy - July 11, 2023 Category: Drugs & Pharmacology Source Type: research
A Comparative Study of Ultrasmall Calcium Carbonate Nanoparticles for Targeting and Imaging Atherosclerotic Plaque
ACS Nano. 2023 Jul 3. doi: 10.1021/acsnano.3c03523. Online ahead of print.ABSTRACTAtherosclerosis is a complex disease that can lead to life-threatening events, such as myocardial infarction and ischemic stroke. Despite the severity of this disease, diagnosing plaque vulnerability remains challenging due to the lack of effective diagnostic tools. Conventional diagnostic protocols lack specificity and fail to predict the type of atherosclerotic lesion and the risk of plaque rupture. To address this issue, technologies are emerging, such as noninvasive medical imaging of atherosclerotic plaque with customized nanotechnologic...
Source: Atherosclerosis - July 3, 2023 Category: Cardiology Authors: Lydia Mart ínez-Parra Marina Pi ñol-Cancer Carlos Sanchez-Cano Ana B Miguel-Coello Desir è Di Silvio Ana M Gomez Clara Uriel Sandra Plaza-Garc ía Marta Gallego Raquel Pazos Hugo Groult Marc Jeannin Kalotina Geraki Laura Fern ández-Méndez Ainhize Urk Source Type: research
Angiotensin-Converting Enzyme and Hypertension: A Systemic Analysis of Various ACE Inhibitors, Their Side Effects, and Bioactive Peptides as a Putative Therapy for Hypertension
J Renin Angiotensin Aldosterone Syst. 2023 Jun 21;2023:7890188. doi: 10.1155/2023/7890188. eCollection 2023.ABSTRACTHypertension is a major risk factor for heart attack, produce atherosclerosis (hardening of the arteries), congestive heart failure, stroke, kidney infection, blindness, end-stage renal infection, and cardiovascular diseases. Many mechanisms are involved in causing hypertension, i.e., via calcium channels, alpha and beta receptors, and the renin-angiotensin system (RAS). RAS has an important role in blood pressure control and is also involved in the metabolism of glucose, homeostasis, and balance of electroly...
Source: Atherosclerosis - June 30, 2023 Category: Cardiology Authors: Hafiz Ahmad Huma Khan Shabirul Haque Shameem Ahmad Namita Srivastava Azhar Khan Source Type: research
A nationwide cohort study comparing the effectiveness of diuretics and calcium channel blockers on top of renin-angiotensin system inhibitors on chronic kidney disease progression and mortality.
It is unknown whether initiating diuretics on top of renin-angiotensin system inhibitors (RASi) is superior to alternative antihypertensive agents such as calcium channel blockers (CCBs) in patients with chronic kidney disease (CKD). For this purpose, we emulated a target trial in the Swedish Renal Registry 2007-2022 that included nephrologist-referred patients with moderate-advanced CKD and treated with RASi, who initiated diuretics or CCB. Using propensity score-weighted cause-specific Cox regression, we compared risks of major adverse kidney events (MAKE; composite of kidney replacement therapy [KRT], experiencing over ...
Source: Kidney International - June 15, 2023 Category: Urology & Nephrology Authors: Anne-Laure Faucon, Edouard L. Fu, B énédicte Stengel, Faizan Mazhar, Marie Evans, Juan-Jesús Carrero Tags: clinical investigation Source Type: research
The association of calcium channel blocker with risk of adverse limb events in patients with chronic limb-threatening ischemia after endovascular treatment
This study highlights the necessity of future studies regarding CCB.Clinical Trial Registration: URL:https://www.umin.ac.jp; Unique identifiers: UMIN000015100.
Source: Cardiovascular Intervention and Therapeutics - April 3, 2023 Category: Cardiology Source Type: research
Association of Beta Blockers and Calcium Channel Blockers with Arrhythmia After Carotid Intervention
Postoperative arrhythmia has a reported incidence of 2% to 4%, which can increase patients ’ risk of developing stroke or myocardial infarction; however, insufficient data are available regarding the prognostic implications and management of arrhythmia after carotid intervention. The aim of this study was to identify the factors associated with arrhythmia after carotid intervention usin g data collected as a part of the Society for Vascular Surgery Vascular Quality Initiative.
Source: Journal of Vascular Surgery - March 17, 2023 Category: Surgery Authors: Teah Qvavadze, Fedor Lurie, Todd Russell Source Type: research
