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Condition: Ischemic Stroke
Management: WHO

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Total 347 results found since Jan 2013.

Citicoline for treating people with acute ischemic stroke.
CONCLUSIONS: This review assessed the clinical benefits and harms of citicoline compared with placebo or any other standard treatment for people with acute ischemic stroke. The findings of the review suggest there may be little to no difference between citicoline and its controls regarding all-cause mortality, disability or dependence in daily activities, severe adverse events, functional recovery and the assessment of the neurological function, based on low-certainty evidence. None of the included trials assessed quality of life and the safety profile of citicoline remains unknown. The available evidence is of low quality...
Source: Cochrane Database of Systematic Reviews - August 28, 2020 Category: General Medicine Authors: Martí-Carvajal AJ, Valli C, Martí-Amarista CE, Solà I, Martí-Fàbregas J, Bonfill Cosp X Tags: Cochrane Database Syst Rev Source Type: research

144: the physiological information role for stroke patients
Conclusion: Each patient should be individually assessed on his or her readiness to receive information. Healthcare professionals should take a patient's age, gender, educational status and communication support needs into account when assessing their need for information. Information should be offered to patients in a variety of formats, including easy access and repeated and re-offered at appropriate intervals.
Source: BMJ Open - February 7, 2017 Category: Journals (General) Authors: Vahdatpour, T., Pourrasmi-Mamaghani, A. Tags: Open access Poster Source Type: research

Acupuncture for acute stroke.
CONCLUSIONS: This updated review indicates that apparently improved outcomes with acupuncture in acute stroke are confounded by the risk of bias related to use of open controls. Adverse events related to acupuncture were reported to be minor and usually did not result in stopping treatment. Future studies are needed to confirm or refute any effects of acupuncture in acute stroke. Trials should clearly report the method of randomization, concealment of allocation, and whether blinding of participants, personnel, and outcome assessors was achieved, while paying close attention to the effects of acupuncture on long-term funct...
Source: Cochrane Database of Systematic Reviews - March 30, 2018 Category: General Medicine Authors: Xu M, Li D, Zhang S Tags: Cochrane Database Syst Rev Source Type: research

Oxidative Stress and Pathophysiology of Ischemic Stroke: Novel Therapeutic Opportunities.
Abstract Stroke is the second leading cause of death, after ischemic heart disease, and accounts for 9% of deaths worldwide. According to the World Health Organization [WHO], 15 million people suffer stroke worldwide each year. Of these, more than 6 million die and another 5 million are permanently disabled. Reactive oxygen species [ROS] have been implicated in brain injury after ischemic stroke. There is evidence that a rapid increase in the production of ROS immediately after acute ischemic stroke rapidly overwhelm antioxidant defences, causing further tissue damage. These ROS can damage cellular macromolecules ...
Source: CNS and Neurological Disorders Drug Targets - February 27, 2013 Category: Drugs & Pharmacology Authors: Rodrigo R, Fernández-Gajardo R, Gutiérrez R, Matamala JM, Carrasco R, Miranda-Merchak A, Feuerhake W Tags: CNS Neurol Disord Drug Targets Source Type: research

Worldwide Analysis of Radiology Access and Education for Stroke Care: View From Abroad From 14 Countries
The World Health Organization reports that stroke is among the leading causes of death in noncommunicable diseases worldwide despite advances in acute stroke care [1]. Early interventions in cerebrovascular accidents can prevent mortality and minimize debilitating effects of stroke. There have been major recent advancements in stroke care to intervene more quickly and effectively. We are entering a new era of stroke imaging-based treatment for late acute ischemic stroke. Recent neurointerventional trials, such as DAWN and DEFUSE 3, have transformed the way clinicians provide acute stroke care in the United States and provi...
Source: Journal of the American College of Radiology : JACR - September 6, 2018 Category: Radiology Authors: Jesus Uribe, Simon Ammanuel, Bhavya Rehani Tags: A View From Abroad Source Type: research

Imprecise eponyms in stroke medicine & #8211; A growing need for uniform terminologies/definitions across the globe
Conclusions: The most imprecise term that continues to be used is “CVA”. The precisely defined entity like “cerebrovascular disease,” which is a group of diseases, continues to be used inappropriately. All the terms are not defined uniformly across the globe, whereas most continue to use the World Health Organisation definition of stroke, defined in the 1970s. It is essential to condemn the use of imprecise terminologies and promote the use of recently defined precise terms “stroke” and “transient ischemic attack (TIA)”....
Source: Neurology India - May 12, 2019 Category: Neurology Authors: Kamble J Harsha Source Type: research

Intravenous thrombolytic treatment and endovascular thrombectomy for ischaemic wake-up stroke
CONCLUSIONS: In selected patients with acute ischaemic wake-up stroke, both intravenous thrombolytic treatment and endovascular thrombectomy of large vessel occlusion improved functional outcome without increasing the risk of death. However, a possible increased risk of symptomatic intracranial haemorrhage associated with thrombolytic treatment cannot be ruled out. The criteria used for selecting patients to treatment differed between the trials. All studies were relatively small, and six of the seven studies were terminated early. More studies are warranted in order to determine the optimal criteria for selecting patients...
Source: Cochrane Database of Systematic Reviews - December 1, 2021 Category: General Medicine Authors: Melinda B Roaldsen Haakon Lindekleiv Ellisiv B Mathiesen Source Type: research

Incidence rate of stroke in Peru
CONCLUSIONS: The incidence of stroke is high in Peru. Ischemic cases are the most frequent and they disproportionately affect men. Our results suggest the need for a surveillance system to robustly quantify the incidence of these cases and understand their determinants.PMID:34932741 | DOI:10.17843/rpmesp.2021.383.7804
Source: Revista Peruana de Medicina de Experimental y Salud Publica - December 21, 2021 Category: International Medicine & Public Health Authors: Antonio Bernab é-Ortiz Rodrigo M Carrillo-Larco Source Type: research