Intravenous thrombolytic treatment and endovascular thrombectomy for ischaemic wake-up stroke

CONCLUSIONS: In selected patients with acute ischaemic wake-up stroke, both intravenous thrombolytic treatment and endovascular thrombectomy of large vessel occlusion improved functional outcome without increasing the risk of death. However, a possible increased risk of symptomatic intracranial haemorrhage associated with thrombolytic treatment cannot be ruled out. The criteria used for selecting patients to treatment differed between the trials. All studies were relatively small, and six of the seven studies were terminated early. More studies are warranted in order to determine the optimal criteria for selecting patients for treatment.PMID:34850380 | DOI:10.1002/14651858.CD010995.pub3
Source: Cochrane Database of Systematic Reviews - Category: General Medicine Authors: Source Type: research