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Efficacy of phosphodiesterase type 5 inhibitors in univentricular congenital heart disease: the SV ‐INHIBITION study design
ConclusionsThe SV ‐INHIBITION study aims to answer the question whether PDE5 inhibitors should be prescribed in patients with an SV. This trial has been built focusing on the three levels of research defined by the World Health Organization: disability (exercise tolerance), deficit (SV function), and handicap (qual ity of life).
Source: ESC Heart Failure - March 9, 2020 Category: Cardiology Authors: Pascal Amedro, Arthur Gavotto, Hamouda Abassi, Marie ‐Christine Picot, Stefan Matecki, Sophie Malekzadeh‐Milani, Marilyne Levy, Magalie Ladouceur, Caroline Ovaert, Philippe Aldebert, Jean‐Benoit Thambo, Alain Fraisse, Marc Humbert, Sara Tags: Study Design Source Type: research

A short review of proprotein convertase subtilisin/kexin type 9 inhibitors.
Authors: Alali RA Abstract Cardiovascular disease is the leading cause of morbidity and mortality globally, as estimated by the World Health Organization, where in 2016, 15.2 million deaths were attributed to ischemic heart disease and stroke. It is therefore essential to try to reduce the incidence of Cardiovascular disease by controlling modifiable risk factors. One such major modifiable risk factor is cholesterol, which influences the pathogenesis and progression of atherosclerosis. Statins are often prescribed to lower blood levels of low density lipoprotein cholesterol, thereby reducing the risk of Cardiovascu...
Source: Reviews in Cardiovascular Medicine - June 13, 2019 Category: Cardiology Tags: Rev Cardiovasc Med Source Type: research

An African cardiology summitThe World Heart Federation African Summit on Best Practices in Policy and Access to Care in 2017 concluded with the Khartoum Action Plan, to improve cardiovascular on the African continent
The World Heart Federation (WHF) is the umbrella organization of continental and national cardiac societies and heart foundations globally, reporting to the World Health Organization (WHO). The WHF is dedicated to the global fight against CVD, including heart disease, stroke, and rheumatic heart disease (RHD). Building on the first Global Summit on Circulatory Health, held at the 2016 World Congress of Cardiology and Cardiovascular Health in Mexico City, the second Summit held in Singapore July 2017 focused on building a civil society movement for circulatory health.
Source: European Heart Journal - February 6, 2018 Category: Cardiology Source Type: research

2017 Guidelines for the management of arterial hypertension in primary health care in Portuguese-speaking countries
Publication date: Available online 29 November 2017 Source:Revista Portuguesa de Cardiologia (English Edition) Author(s): Gláucia Maria Moraes de Oliveira, Miguel Mendes, Marcus Vinícius Bolívar Malachias, João Morais, Osni Moreira Filho, Armando Serra Coelho, Daniel Pires Capingana, Vanda Azevedo, Irenita Soares, Alda Menete, Beatriz Ferreira, Miryan Bandeira dos Prazeres Cassandra Soares, Mário Fernandes The World Health Organization goal's to reduce mortality due to chronic non-communicable diseases by 2% per year demands a huge effort from member countries. This challenge for health professionals requires global ...
Source: Revista Portuguesa de Cardiologia - November 29, 2017 Category: Cardiology Source Type: research

Potential Cardiovascular and Total Mortality Benefits of Air Pollution Control in Urban China.
Conclusions -Air quality improvement at different scenarios could lead to graded health benefits ranging from 241,000 life-years gained to much greater benefits are equal to or greater than the combined benefits of 25% improvement in systolic hypertension control and 30% smoking reduction. PMID: 28882886 [PubMed - as supplied by publisher]
Source: Circulation - September 7, 2017 Category: Cardiology Authors: Huang C, Moran AE, Coxson PG, Yang X, Liu F, Cao J, Chen K, Wang M, He J, Goldman L, Zhao D, Kinney PL, Gu D Tags: Circulation Source Type: research

Pathophysiologic role of ischemia reperfusion injury: a review
Publication date: Available online 19 June 2017 Source:Journal of Indian College of Cardiology Author(s): Vishal Kumar Vishwakarma, Prabhat Kumar Upadhyay, Jeetendra Kumar Gupta, Harlokesh Narayan Yadav Ischemic heart disease (IHD) is the major cause of morbidity and mortality all over the world. World health organization (WHO) in 2002 assumed that IHD may be the major leading cause of death by 2020. An estimated 17 million people died from cardiovascular diseases (CVS) globally. Of these deaths, 7 million people died by ischemia heart disease and 6.2 million by stroke. Ischemia is defined as an insufficient supply of the...
Source: Journal of Indian College of Cardiology - June 19, 2017 Category: Cardiology Source Type: research

PS025 La Carta De Santiago: Priorities for Stroke Prevention and Treatment in the Americas
According to the World Health Organization (WHO), stroke claims 5.5 million lives globally each year. As the No. 2 killer worldwide, it is estimated that 17.3 million people die from cardiovascular disease including stroke each year, representing 30% of all global deaths. That equates to six people dying from stroke every 60 seconds and unfortunately the burden of stroke is disproportionately affecting low to middle income countries exceeding those of high income countries by 20%.[1] In some Latin American countries, ischemic heart disease and stroke are ranked as the No.
Source: CVD Prevention and Control - May 27, 2016 Category: Cardiology Authors: S. Cruz Flores, D. Vaca McGhie, Latin American Leadership Steering Group for Latin American Summit Tags: Poster Abstract Source Type: research

Adherence to Medical Therapy and the Global Burden of Cardiovascular Disease ∗
Ischemic heart disease and cerebrovascular disease account for>20% of worldwide mortality and are the 2 leading causes of death on a global basis (1). Although mortality from ischemic heart disease is greater than that from stroke worldwide, the mortality from stroke is actually higher than from ischemic heart disease in 39% of countries. For example, mortality from stroke is generally higher than that for ischemic heart disease in China, Africa, and South America. In addition, stroke disability–adjusted life-year loss rates exceed ischemic heart disease-related disability in 32% of countries (2). Because of this, strate...
Source: Journal of the American College of Cardiology - March 29, 2016 Category: Cardiology Source Type: research

The Global Burden of Cardiovascular Diseases, 1990–2010
Cardiovascular diseases (CVD), principally ischemic heart disease and stroke, remain the leading cause of mortality worldwide and a major contributor to disability and rising healthcare costs . In 2010 alone, CVD was a primary cause of 15.6 million global deaths and an estimated US$863 billion in direct healthcare costs and productivity losses worldwide . In fact, these costs are projected to reach US$20 trillion by the year 2030 . In spite of this huge toll on global health and development, reports from the Institute of Medicine, the World Heart Federation, and the World Health Organization state that CVD is rarely on the...
Source: CVD Prevention and Control - March 1, 2014 Category: Cardiology Authors: George A. Mensah, Andrew E. Moran, Gregory A. Roth, Jagat Narula Tags: Editor's Page Source Type: research

President's Page: Heart Month and the American College of Cardiology: A Lesson in Partnerships, Member Values, and Patient Education
The global statistics surrounding cardiovascular disease speak for themselves. Not only is cardiovascular disease the number 1 cause of death globally, but this trend is also expected to continue well into the future. According to the World Health Organization, the number of deaths from cardiovascular diseases, mainly from heart disease and stroke, is expected to reach 23.3 million by 2030 .
Source: Journal of the American College of Cardiology - February 3, 2014 Category: Cardiology Authors: John Gordon Harold Tags: FROM THE ACC Source Type: research

Sexual counselling for individuals with cardiovascular disease and their partners: A Consensus Document From the American Heart Association and the ESC Council on Cardiovascular Nursing and Allied Professions (CCNAP)
After a cardiovascular event, patients and their families often cope with numerous changes in their lives, including dealing with consequences of the disease or its treatment on their daily lives and functioning. Coping poorly with both physical and psychological challenges may lead to impaired quality of life. Sexuality is one aspect of quality of life that is important for many patients and partners that may be adversely affected by a cardiac event. The World Health Organization defines sexual health as ‘... a state of physical, emotional, mental and social well-being in relation to sexuality; it is not merely the ...
Source: European Heart Journal - November 1, 2013 Category: Cardiology Authors: Steinke, E. E., Jaarsma, T., Barnason, S. A., Byrne, M., Doherty, S., Dougherty, C. M., Fridlund, B., Kautz, D. D., Martensson, J., Mosack, V., Moser, D. K., on behalf of the Council on Cardiovascular and Stroke Nursing of the American Heart Association a Tags: ESC POSITION PAPER Source Type: research

The “know your numbers” program in Atahualpa — A pilot study aimed to reduce cardiovascular diseases and stroke burden in rural communities of developing countries
The burden of cardiovascular diseases and stroke is steadily increasing in many low- and middle-income countries, to the point that these conditions have been considered as the new epidemics of the developing world . The World Health Organization has set a global goal of reducing deaths from non-communicable diseases (including stroke and ischemic heart disease) by 25% by 2025 . It seems that people living in rural communities are most vulnerable to these “new epidemics”. There, a process of epidemiologic transition is aggravated by poor access to medical care and by income issues that preclude people to afford the cos...
Source: International Journal of Cardiology - May 6, 2013 Category: Cardiology Authors: Oscar H. Del Brutto, Martha Montalván, Daniel Tettamanti, Ernesto Peñaherrera, Rocío Santibáñez, Freddy Pow-Chon-Long, Victor J. Del Brutto Tags: Letters to the Editor Source Type: research