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NAMPT as a Dedifferentiation-Inducer Gene: NAD+ as Core Axis for Glioma Cancer Stem-Like Cells Maintenance
Conclusion and Perspectives
Gliomas are the most prevalent primary brain cancer in adults and include a broad category of tumors including astrocytoma, oligodendroglioma, and GBM. Regardless of tumor aggressiveness, malignancy, and infiltration, these glia-derived tumors rarely exceed a median survival time of 12–14 months. Driven by the infiltrative nature of these tumors, the clinical approach is difficult and relapses often occur with fatal consequences. These unsuccessful attempts to control glioma's fate have fostered research looking for more effective therapies.
(GSCs) are a small subset of CD133&#...
Source: Frontiers in Oncology - May 2, 2019 Category: Cancer & Oncology Source Type: research
High-Fiber Diet Linked To Lower Risk Of Death And Chronic Illness
(CNN) — People who eat diets that are high in fiber have lower risk of death and chronic diseases such as stroke or cancer compared with people with low fiber intake, a new analysis found.
Dietary fiber includes plant-based carbohydrates such as whole-grain cereal, seeds and some legumes. Fiber’s health benefits have been recorded “by over 100 years of research,” Andrew Reynolds, a researcher at the University of Otago in New Zealand, wrote in an email. He is co-author of the new meta-analysis of existing research, which was published Thursday in the journal The Lancet.
The research shows that high...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - January 11, 2019 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health News CNN fiber Local TV Source Type: news
Want to Prevent the Deadliest Diseases? Eat More Fiber
If you want to eat something for better health, make it fiber. That’s the advice from nutrition experts and the latest national dietary guidelines.
Now, a large new review of studies on fiber, published in the Lancet, shows just how beneficial fiber can be. The nutrient substantially lowers the risk of at least four diseases—many of which don’t even directly relate to the gut.
Compared to those who ate less fiber, people who ate more fiber lowered their risk of heart disease, stroke, type 2 diabetes and colon cancer, as well as their risk of dying early from any cause, by 15% to 30%. And the more dietary ...
Source: TIME: Health - January 10, 2019 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized Cancer Diet/Nutrition healthytime Heart Disease Source Type: news
Image-based screening.
Abstract
Screening is a special issue in medical questions concerning disease prevention. Preconditions for screening are clearly defined by the World Health Organization. High prevalence, effectiveness of therapy, availability of accepted test procedure and consensus concerning the economic concerns are necessary for successful implementation of a screening program. Preventive diagnostic studies can only be understood if one is familiar with the statistical terms sensitivity, specificity, prevalence, incidence and bias (especially overdiagnosis and lead time bias). Aspects of radiation protection are especially...
Source: Der Radiologe - December 14, 2018 Category: Radiology Authors: Layer G Tags: Radiologe Source Type: research
Want to Prevent Stroke, Diabetes, Cancer? Get Moving … Now!
Worldwide, 81 per cent of school-aged children are not active enough. Photo: WHOBy Baher KamalROME, Feb 2 2017 (IPS)Tired, lazy, bored, laying down long hours watching TV or seated checking your email? Wrong. And dangerous: not enough exercise contributes to cancer, diabetes, depression and other non-communicable diseases. The warning is bold and comes from the United Nations top health organisation, which is urging people to get up and get active.And the risks of inactivity are expanding alarmingly: according to a new document by the World Health Organization (WHO), less and less people are active in many countries – wi...
Source: IPS Inter Press Service - Health - February 2, 2017 Category: Global & Universal Authors: Baher Kamal Tags: Environment Featured Global Headlines Health IPS UN: Inside the Glasshouse TerraViva United Nations Source Type: news
From Conference To Clinic: The Longest Yard On Nutrition
The contrast between science and clinical practice can be so stark that it is shocking. I just returned from Washington, D.C. and the International Conference on Nutrition in Medicine sponsored by the Physicians Committee for Responsible Medicine and the Georgetown University School of Medicine. The first patient I saw in my preventive cardiology clinic after returning from the conference described his 25 year struggle with heart disease including 2 separate bypass operations, numerous stents, and activity severely limited by angina chest pain. He could barely walk to the mailbox without taking a nitro tablet under his ton...
Source: Healthy Living - The Huffington Post - August 9, 2016 Category: Consumer Health News Source Type: news
Our Sedentary Lifestyles Cost About 5 Million Lives A Year
By Kate Kelland
LONDON (Reuters) - A study of one million people has found that physical inactivity costs the global economy $67.5 billion a year in healthcare and productivity losses, but an hour a day of exercise could eliminate most of that.
Sedentary lifestyles are linked to increased risks of heart disease, diabetes and cancer, researchers found, but activity - such as brisk walking - could counter the higher likelihood of early death linked with sitting for eight or more hours a day.
Such inactivity is estimated to cause more than 5 million deaths a year - almost as many as smoking, which the World Health Organi...
Source: Healthy Living - The Huffington Post - July 28, 2016 Category: Consumer Health News Source Type: news
Exercise to Extend Your Life
by Phil Hardesty
Imagine if there was a pill you could take that was free and would virtually eliminate, or at least minimize most disease processes. It would provide you with energy and strength to live your life beyond what you thought was possible. Everyone would want this pill and if it worked as well as it promised, just think of how healthy our population may be.
Of course this "pill" does exist. It's called regular physical activity and exercise.
According to the World Health Organization's Global Health Risks data physical inactivity is the fourth leading cause of death globally only behind high blood pressure, ...
Source: Healthy Living - The Huffington Post - May 9, 2016 Category: Consumer Health News Source Type: news
Obesity in the U.S. and Europe on the Rise: A Comparison
Levels of obesity in adults and children are rising worldwide. The World Health Organization calls the rising level "an epidemic" citing sugary drinks and processed foods as the main culprits, along with an urban sedentary lifestyle.
A study published in The Lancet named "Global, regional, and national prevalence of overweight and obesity in children and adults during 1980-2013: a systematic analysis for the Global Burden of Disease Study 2013" stated obesity issues "were estimated to have caused 3.4 million deaths globally, most of which were from cardiovascular causes. Research indicates that if left unaddressed, the ri...
Source: Healthy Living - The Huffington Post - May 5, 2016 Category: Consumer Health News Source Type: news
2016 Moon Shot for Cancer: Focus on Prevention
It is now 2016, and Americans hope for a brighter, healthier new year. Are Americans healthier today than they were last year or the year before? Will there be fewer people diagnosed with cancer? According to the American Cancer Society, it is projected that in 2016 there will be 1,685,210 new cancer cases and 595,690 deaths due to cancer. This is an increase over previous years. While it is true that the death rate for several cancers has decreased (due mostly to better screening and earlier diagnosis), it is also true that several cancers are on the rise, including cancers of the thyroid, liver, pancreas, kidney, small i...
Source: Healthy Living - The Huffington Post - February 1, 2016 Category: Consumer Health News Source Type: news
The Stigma Ends Now
Did you smoke? That is often one of the first responses patients hear when they tell people about their lung cancer diagnosis. For decades lung cancer has been singled out as THE smoker's disease, despite evidence that over 30 other deadly diseases are directly linked to tobacco consumption. In fact, a recent study published in the New England Journal of Medicine found that breast cancer, prostate cancer, kidney failure and diabetes are among those smoking-related diseases. This connection between tobacco and serious illnesses other than lung cancer has been known for quite a while. The U.S. surgeon general lists smoking ...
Source: Healthy Living - The Huffington Post - November 13, 2015 Category: Consumer Health News Source Type: news
HRT increases ovarian cancer risk by small amount
Conclusion
This systematic review and meta-analysis showed that ovarian cancer risk was significantly increased in current HRT users, even in those with less than five years of HRT use (the average was three years). In ex-users, risks decreased the longer ago HRT use had stopped, but risks during the first few years after stopping remained significant. Furthermore, about a decade after stopping, long-duration hormone therapy use (average nine years of HRT use), there still seemed to be a small excess risk.
The review has a few limitations, however. The main one is that the review was heavily influenced by just two of t...
Source: NHS News Feed - February 13, 2015 Category: Consumer Health News Tags: Cancer Medication Older people Source Type: news
