2016 Moon Shot for Cancer: Focus on Prevention

It is now 2016, and Americans hope for a brighter, healthier new year. Are Americans healthier today than they were last year or the year before? Will there be fewer people diagnosed with cancer? According to the American Cancer Society, it is projected that in 2016 there will be 1,685,210 new cancer cases and 595,690 deaths due to cancer. This is an increase over previous years. While it is true that the death rate for several cancers has decreased (due mostly to better screening and earlier diagnosis), it is also true that several cancers are on the rise, including cancers of the thyroid, liver, pancreas, kidney, small intestine, tongue and tonsil in both women and men. In women, the incidence of endometrial, vulvar and anal cancer is rising. In men, there is an increase in the incidence of melanoma, multiple myeloma, male breast cancer, testicular cancer and throat cancer. It is also alarming that cancer-incidence rates in children have increased steadily since 1975. Leukemia, and cancers of the brain and other nervous-system tumors are the most frequently occurring childhood malignancies. Cancer rates are strongly impacted by the rise in obesity. Unfortunately, obesity rates in America have increased over the past 10 years. Between 1999 and 2014, our nation's obesity rate rose 24 percent among children and adults. Now, more than one-third (79 million) adults in the United States are obese. Why is this a problem? The answer is that obesity increases the risk of several typ...
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news

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Conclusion: This study suggests that a higher OBS is associated with more favorable levels of IL-6 and CRP, and that the association of OBS and IL-6 may be modified by CKD status.Nephron Extra 2018;8:11 –23
Source: Nephron Extra - Category: Urology & Nephrology Source Type: research
A video of the very sweet moment a young Tennessee girl learned she was cancer-free has gone viral.
Source: ABC News: Health - Category: Consumer Health News Tags: Health Source Type: news
Drug overdose deaths more than doubled between 2005 and 2016, according to the Commonwealth Fund's 2018 Scorecard on State Health System Performance. In a new To the Point post, the Commonwealth Fund's Susan Hayes, David Radley, and Douglas McCarthy compare state rates for deaths from drug overdoses, as well as alcohol abuse and suicide, using the most recently available data. The authors also highlight successful strategies for expanding access to opioid addiction treatment, which often rely on cooperation and engagement across the health care, social service, and criminal justice sectors.        
Source: The Commonwealth Fund: Publications - Category: International Medicine & Public Health Source Type: research
Authors: Emmanuel S, Jornayvaz FR Abstract Discovered 20 years ago, Fibroblast Growth Factor (FGF) 19, and its mouse ortholog FGF15, were the first members of a new subfamily of FGFs able to act as hormones. During fetal life, FGF15/19 is involved in organogenesis, affecting the development of the ear, eye, heart and brain. At adulthood, FGF15/19 is mainly produced by the ileum, acting on the liver to repress hepatic bile acid synthesis and promote postprandial nutrient partitioning. In rodents, pharmacologic doses of FGF19 induce the same anti-obesity and anti-diabetic actions as FGF21, these metabolic effects bei...
Source: Endocrine Reviews - Category: Endocrinology Tags: Endocr Rev Source Type: research
STEFAN KARL STEFANSSON, the LazyTown actor that starred as Robbie Rotten, has died after a battle with bile duct cancer. Bile duct cancer symptoms include  itchy skin and weight loss - these are the warning signs to look out for.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Authors: Mouodi S, Hosseini SR, Ghadimi R, Bijani A, Cumming RG, Amiri HA, Bayani F, Sum S Abstract Background: The purpose of this study was to determine the current situation of lifestyle behaviors and related outcomes, as the first step to make proper local health policies for improvement of health lifestyle behaviors. Materials and Methods: This analytic research has been conducted as a cross-sectional study on the middle-aged (40-60 years old) population of Amirkola, Northern Iran. The Persian translation of the Health-Promoting Lifestyle Profile II questionnaire and the International Physical Activity Que...
Source: Journal of Obesity - Category: Eating Disorders & Weight Management Tags: J Obes Source Type: research
Authors: Krakauer NY, Krakauer JC Abstract Independent indices (height, body mass index, a body shape index, and hip index) derived from basic anthropometrics have been found to be powerful predictors of mortality hazard, especially when the attributable risks are summed over these indices to give an anthropometric risk index (ARI). The metabolic syndrome (MS) is defined based on the co-occurrence of anthropometric, clinical, and laboratory criteria and is also widely employed for evaluating disease risk. Here, we investigate correlations between ARI and MS in a general population sample, the United States Third Na...
Source: Journal of Obesity - Category: Eating Disorders & Weight Management Tags: J Obes Source Type: research
Authors: Morin I, Bégin C, Maltais-Giguère J, Bédard A, Tchernof A, Lemieux S Abstract Weight loss has been associated with changes in eating behaviors and appetite sensations that favor a regain in body weight. Since traditional weight loss approaches emphasize the importance of increasing cognitive dietary restraint (CDR) to achieve negative energy imbalance, it is difficult to untangle the respective contributions of energy restriction and increases in CDR on factors that can eventually lead to body weight regain. The present study aimed at comparing the effects of energy restriction alone o...
Source: Journal of Obesity - Category: Eating Disorders & Weight Management Tags: J Obes Source Type: research
Corrigendum to "Sequence Analysis of the UCP1 Gene in a Severe Obese Population from Southern Italy". J Obes. 2018;2018:3260210 Authors: Labruna G, Pasanisi F, Fortunato G, Nardelli C, Finelli C, Farinaro E, Contaldo F, Sacchetti L Abstract [This corrects the article DOI: 10.1155/2011/269043.]. PMID: 30123581 [PubMed - in process]
Source: Journal of Obesity - Category: Eating Disorders & Weight Management Tags: J Obes Source Type: research
(Reuters Health) - Subtle variations in millions of genes contribute to individual risk for common illnesses like heart disease and diabetes - and putting them all together into a "polygenic" risk profile can identify many more people with higher than average odds of getting sick, researchers say.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news
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