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Management: Electronic Health Records (EHR)

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Total 477 results found since Jan 2013.

Risk factors and treatment of oxygenator high-pressure excursions during cardiopulmonary bypass
CONCLUSIONS: Large body surface area, high hematocrit during CPB, previous stroke and acute surgery were independently associated with HPE. A treatment protocol including epoprostenol appears to be a safe option. Perioperative stroke rate was increased in HPE patients.PMID:34510993 | DOI:10.1177/02676591211043700
Source: Perfusion - September 13, 2021 Category: Cardiovascular & Thoracic Surgery Authors: Anders Karl Hj ärpe Anders Jeppsson Lukas Lannemyr Martin Lindgren Source Type: research

Prediction of incident atrial fibrillation in community-based electronic health records: a systematic review with meta-analysis
Conclusions Models externally validated for prediction of incident AF in community-based EHR demonstrate moderate predictive ability and high risk of bias. Novel methods may provide stronger discriminative performance. Systematic review registration PROSPERO CRD42021245093.
Source: Heart - June 10, 2022 Category: Cardiology Authors: Nadarajah, R., Alsaeed, E., Hurdus, B., Aktaa, S., Hogg, D., Bates, M. G. D., Cowan, C., Wu, J., Gale, C. P. Tags: Open access Arrhythmias and sudden death Source Type: research

Comparative Safety of BNT162b2 and mRNA-1273 Vaccines in a Nationwide Cohort of US Veterans
CONCLUSIONS AND RELEVANCE: The findings of this cohort study suggest that there were few differences in risk of adverse events within 14 days of the first dose of either the BNT162b2 or the mRNA-1273 vaccine and small-magnitude differences within 42 days of the first dose. The 38-week risks of adverse events were low in both vaccine groups, although risks were lower for recipients of the mRNA-1273 vaccine than for recipients of the BNT162b2 vaccine. Although the primary analysis was designed to detect safety events unrelated to SARS-CoV-2 infection, the possibility that these differences may partially be explained by a low...
Source: Herpes - June 13, 2022 Category: Infectious Diseases Authors: Barbra A Dickerman Arin L Madenci Hanna Gerlovin Katherine E Kurgansky Jessica K Wise Michael J Figueroa Mu ñiz Brian R Ferolito David R Gagnon J Michael Gaziano Kelly Cho Juan P Casas Miguel A Hern án Source Type: research

Cluster randomized trials utilizing primary care electronic health records: methodological issues in design, conduct, and analysis (eCRT Study)
Conclusions: Cluster randomized trials may be performed efficiently in large samples from UK general practices using the electronic health records of a primary care database. The geographical dispersal of trial sites presents a difficulty for research governance approval and intervention implementation. Pretrial data analyses should inform trial design and analysis plans.Trial registration: Current Controlled Trials ISRCTN 47558792 and ISRCTN 35701810 (both registered on 17 March 2010).
Source: BioMed Central - June 11, 2014 Category: Journals (General) Authors: Martin C GullifordTjeerd P van StaaLisa McDermottGerard McCannJudith CharltonAlex Dregan Source Type: research

Abstract 146: Clinical and Economic Consequences of Statin Intolerance in the U.S.: Results from an Integrated Health System Session Title: Poster Session I
Conclusion: While the majority of SI patients were on a statin, SI patients demonstrate a higher risk of some cardiovascular events; incur higher healthcare costs; and difficulty reaching LDL-C goals compared to patients without SI. Alternative treatment strategies are needed to better serve this at-risk patient population.
Source: Circulation: Cardiovascular Quality and Outcomes - April 29, 2015 Category: Cardiology Authors: Sanchez, R. J., Graham, J. H., Evans, M. A., Mallya, U. G., Panaccio, M. P., Steinhubl, S. R. Tags: Session Title: Poster Session I Source Type: research

Understanding Population Cardiovascular Health: Harnessing the Power of Electronic Health Records.
Abstract In 2004 the American Heart Association (AHA) set forth an ambitious strategic goal for 2010 to 1) reduce death from coronary heart disease and stroke by 25%, 2) reduce the prevalence of smoking, high cholesterol, uncontrolled hypertension, and physical inactivity by 25%, and 3) to stop increases in obesity and diabetes relative to rates in 1999. Having achieved or exceeded goals 1 and 2 by 2008 through a number of collaborative efforts, including public education, practice guidelines and quality improvement initiatives, in 2009, the AHA reframed its focus more broadly to one of achieving increased levels ...
Source: Circulation - September 1, 2015 Category: Cardiology Authors: Newby LK Tags: Circulation Source Type: research

Usual blood pressure, atrial fibrillation and vascular risk: evidence from 4.3 million adults
Conclusions:</strong> The association between elevated blood pressure and AF attenuates with increasing age. AF without antithrombotic usage is associated with an increased risk of eight vascular events.</span>
Source: International Journal of Epidemiology - April 28, 2016 Category: Epidemiology Source Type: research

Crowdsourcing the Million Brains Initiative —Reply
In Reply The enthusiasm expressed for the Million Brains Initiative and the thoughtful consideration of ethical facets by Byram and Illes are much appreciated. The authors underscore a few of the inevitable ramifications that will undoubtedly parallel the realization of precision stroke medicine and the transformation from blissful ignorance to big data in stroke medicine. The current paradigm for cerebrovascular disorders from stroke to dementia is founded on individual clinical symptoms that prompt the acquisition, routine interpretation, and archiving of neuroimaging results. Impressions are readily generated and docume...
Source: JAMA Neurology - June 12, 2017 Category: Neurology Source Type: research

Validity of Cardiovascular Disease Event Ascertainment Using Linkage to UK Hospital Records
Conclusion: Our analyses support the validity of cardiovascular disease ascertainment using linkage to the UK Hospital Episode Statistics database records by showing agreement with high resolution disease data collected in the Whitehall II cohort.
Source: Epidemiology - August 2, 2017 Category: Epidemiology Tags: Validation Studies Source Type: research

Impact of metformin on cardiovascular disease: a meta-analysis of randomised trials among people with type 2 diabetes
Conclusions/interpretationThere remains uncertainty about whether metformin reduces risk of cardiovascular disease among patients with type 2 diabetes, for whom it is the recommended first-line drug. Although this is mainly due to absence of evidence, it is unlikely that a definitive placebo-controlled cardiovascular endpoint trial among people with diabetes will be forthcoming. Alternative approaches to reduce the uncertainty include the use of electronic health records in long-term pragmatic evaluations, inclusion of metformin in factorial trials, publication of cardiovascular outcome data from adverse event reporting in...
Source: Diabetologia - August 2, 2017 Category: Endocrinology Source Type: research

Unusual Symptoms of Coronavirus: What We Know So Far
While most people are familiar with the hallmark symptoms of COVID-19 by now—cough, fever, muscle aches, headaches and difficulty breathing—a new crop of medical conditions are emerging from the more than 4 million confirmed cases of the disease around the world. These include skin rashes, diarrhea, kidney abnormalities and potentially life-threatening blood clots. It’s not unusual for viruses to directly infect and affect different tissues and organs in the body, but it is a bit unusual for a primarily respiratory virus like SARS-CoV-2, which is responsible for COVID-19, to have such a wide-ranging reach...
Source: TIME: Health - May 19, 2020 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized COVID-19 Source Type: news

Practice Gap in Atrial Fibrillation Oral Anticoagulation Prescribing at Emergency Department Home Discharge
Introduction: Current U.S. cardiology guidelines recommend oral anticoagulation (OAC) to reduce stroke risk in selected patients with atrial fibrillation (AF), but no formal AF OAC recommendations exist to guide emergency medicine clinicians in the acute care setting. We sought to characterize emergency department (ED) OAC prescribing practices after an ED AF diagnosis.Methods: This retrospective study included index visits for OAC-naive patients ≥18 years old who were discharged home from the ED at an urban, academic, tertiary hospital with a primary diagnosis of AF from 2012-2014. Five hypothesis-blinded, chart reviewe...
Source: Western Journal of Emergency Medicine - June 29, 2020 Category: Emergency Medicine Source Type: research

Weight Change and the Onset of Cardiovascular Diseases: Emulating Trials Using Electronic Health Records
Conclusion: Among individuals with obesity, the weight-loss group had a lower risk of coronary heart disease but not of stroke. Weight gain was associated with increased risk of CVD across BMI groups. See video abstract at, http://links.lww.com/EDE/B838.
Source: Epidemiology - August 3, 2021 Category: Epidemiology Tags: Chronic Diseases Source Type: research

Predicting patient-level new-onset atrial fibrillation from population-based nationwide electronic health records: protocol of FIND-AF for developing a precision medicine prediction model using artificial intelligence
Introduction Atrial fibrillation (AF) is a major cardiovascular health problem: it is common, chronic and incurs substantial healthcare expenditure because of stroke. Oral anticoagulation reduces the risk of thromboembolic stroke in those at higher risk; but for a number of patients, stroke is the first manifestation of undetected AF. There is a rationale for the early diagnosis of AF, before the first complication occurs, but population-based screening is not recommended. Previous prediction models have been limited by their data sources and methodologies. An accurate model that uses existing routinely collected data is n...
Source: BMJ Open - November 2, 2021 Category: General Medicine Authors: Nadarajah, R., Wu, J., Frangi, A. F., Hogg, D., Cowan, C., Gale, C. Tags: Open access, Cardiovascular medicine Source Type: research