Abstract 146: Clinical and Economic Consequences of Statin Intolerance in the U.S.: Results from an Integrated Health System Session Title: Poster Session I
Background: Low-density lipoprotein cholesterol (LDL-C) is a key therapeutic target for reducing risk of cardiovascular (CV) events. While statins are the mainstay of therapy due to efficacy and safety, observational studies indicate patients prescribed statins are unable to tolerate them to varying degrees. The study objective was to examine the clinical and economic consequences of statin intolerance (SI) comparing SI patients to non-SI patients on statin therapy.Methods: This retrospective cohort study used data from an integrated health system’s electronic health record from 2009-2014. Adult patients diagnosed as statin intolerant (identified through a custom diagnosis code), with ≥ 6 months pre- and post-index date eligibility were considered for the study. All patients were hierarchically ordered into 6 mutually exclusive CV risk categories: recent acute coronary syndrome (ACS,
ConclusionsPatients with CMS were more likely to present with increased comorbidities. Patients with CMS undergoing CABG were at risk for worse short ‐term secondary postoperative outcomes and reduced long‐term survival. The data supports the need for further investigation for risk reduction surrounding operative revascularization.
Conclusion: the moments of discussion favored by this study served as learning to continue the future implementation of the strategies pointed out by the group and thus increasingly improve the care provided to patients with heart disease and their families.RESUMEN Objetivo: identificar, junto con el equipo de enfermer ía, estrategias para promover la seguridad del paciente en tratamiento con warfarina. Método: investigación exploratoria y descriptiva con enfoque cualitativo, realizada en las unidades de internación clínica/quirúrgica de un hospital público de referencia en ...
Balance and ambulation are the result of a multicomponent control process through the interaction of the sensory and motor information. Despite the clinical relevance of the somatosensory system, its role has not drawn much attention from clinical research...
Condition: Diabetes Mellitus Interventions: Other: Administration of standardized questionnaires; Device: Physical activity tracker; Other: Dietary log Sponsor: McGill University Health Centre/Research Institute of the McGill University Health Centre Recruiting
Condition: Coronary Artery Disease Interventions: Diagnostic Test: CT angiography; Diagnostic Test: Invasive coronary angiography Sponsors: Johns Hopkins University; Canon Medical Systems Recruiting
Condition: Stroke Interventions: Device: WBPC; Device: Without WBPC Sponsor: Changhua Christian Hospital Completed
Condition: Diabetes Mellitus, Type 2 Interventions: Other: Mobile Application-Based Diabetes Education; Other: Health Coaching Sponsor: Indonesia University Active, not recruiting
Condition: Gestational Diabetes Mellitus Intervention: Behavioral: Low Glycemic Index Education Sponsors: IWK Health Centre; Mount Saint Vincent University; Dalhousie University; The Hospital for Sick Children Recruiting
Condition: Familial Hypercholesterolemia Intervention: Sponsor: Imperial College London Recruiting
Hongfei Gu1†, Shuang Shao2†, Jie Liu3,4,5, Zhenqian Fan2, Yu Chen2, Jingxian Ni3,4,5, Conglin Wang6, Jun Tu3,4,5, Xianjia Ning3,4,5, Yongzhong Lou1*, Bin Li1* and Jinghua Wang3,4,5* 1Department of Neurology, Tianjin Haibin People's Hospital, Tianjin, China 2Department of Endocrinology and Metabolism, The Second Hospital of Tianjin Medical University, Tianjin, China 3Department of Neurology, Tianjin Medical University General Hospital, Tianjin, China 4Laboratory of Epidemiology, Tianjin Neurological Institute, Tianjin, China 5Key Laboratory of Post-Neuroinjury Neuro-Repair and Regeneration i...