Abstract 146: Clinical and Economic Consequences of Statin Intolerance in the U.S.: Results from an Integrated Health System Session Title: Poster Session I

Background: Low-density lipoprotein cholesterol (LDL-C) is a key therapeutic target for reducing risk of cardiovascular (CV) events. While statins are the mainstay of therapy due to efficacy and safety, observational studies indicate patients prescribed statins are unable to tolerate them to varying degrees. The study objective was to examine the clinical and economic consequences of statin intolerance (SI) comparing SI patients to non-SI patients on statin therapy.Methods: This retrospective cohort study used data from an integrated health system’s electronic health record from 2009-2014. Adult patients diagnosed as statin intolerant (identified through a custom diagnosis code), with ≥ 6 months pre- and post-index date eligibility were considered for the study. All patients were hierarchically ordered into 6 mutually exclusive CV risk categories: recent acute coronary syndrome (ACS,
Source: Circulation: Cardiovascular Quality and Outcomes - Category: Cardiology Authors: Tags: Session Title: Poster Session I Source Type: research

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