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Peroxiredoxin-3 Plays a Neuroprotective Role in Early Brain Injury after Experimental Subarachnoid Hemorrhage in Rats
In conclusion, PRDX3 participates in neuronal protection by inhibiting the neuronal mitochondria-mediated death pathway; PRDX3 may be an important target for EBI intervention after SAH.PMID:36566946 | DOI:10.1016/j.brainresbull.2022.12.010
Source: Brain Research - December 25, 2022 Category: Neurology Authors: Haibo Li Zongqi Wang Xueshun Xie Muyun Luo Haitao Shen Xiang Li Haiying Li Zhong Wang Xiangdong Li Gang Chen Source Type: research

Peroxiredoxin-3 plays a neuroprotective role in early brain injury after experimental subarachnoid hemorrhage in rats
In conclusion, PRDX3 participates in neuronal protection by inhibiting the neuronal mitochondria-mediated death pathway; PRDX3 may be an important target for EBI intervention after SAH.PMID:36566946 | DOI:10.1016/j.brainresbull.2022.12.010
Source: Brain Research Bulletin - December 25, 2022 Category: Neurology Authors: Haibo Li Zongqi Wang Xueshun Xie Muyun Luo Haitao Shen Xiang Li Haiying Li Zhong Wang Xiangdong Li Gang Chen Source Type: research

Peroxiredoxin-3 Plays a Neuroprotective Role in Early Brain Injury after Experimental Subarachnoid Hemorrhage in Rats
In conclusion, PRDX3 participates in neuronal protection by inhibiting the neuronal mitochondria-mediated death pathway; PRDX3 may be an important target for EBI intervention after SAH.PMID:36566946 | DOI:10.1016/j.brainresbull.2022.12.010
Source: Brain Research Bulletin - December 25, 2022 Category: Neurology Authors: Haibo Li Zongqi Wang Xueshun Xie Muyun Luo Haitao Shen Xiang Li Haiying Li Zhong Wang Xiangdong Li Gang Chen Source Type: research

MST1 Suppression Reduces Early Brain Injury by Inhibiting the NF- κB/MMP-9 Pathway after Subarachnoid Hemorrhage in Mice.
Conclusions: The current findings indicate that MST1 participates in SAH-induced BBB disruption and white matter fiber damage via the downstream NF-κB-MMP-9 signaling pathway. Therefore, MST1 antagonists may serve as a novel therapeutic target to prevent early brain injury in SAH patients. PMID: 30018671 [PubMed - in process]
Source: Behavioural Neurology - July 20, 2018 Category: Neurology Authors: Qu J, Zhao H, Li Q, Pan P, Ma K, Liu X, Feng H, Chen Y Tags: Behav Neurol Source Type: research

Peroxisome Proliferator-Activated Receptor {beta}/{delta} Alleviates Early Brain Injury After Subarachnoid Hemorrhage in Rats Basic Sciences
Conclusions— PPARβ/’s overexpression may attenuate early brain injury after rats’ SAH administration, which reduces neural apoptosis possibly through blocking NF-B/MMP-9 pathway.
Source: Stroke - December 28, 2015 Category: Neurology Authors: Teng, Z., Jiang, L., Hu, Q., He, Y., Guo, Z., Wu, Y., Huang, Z., Cao, F., Cheng, C., Sun, X., Guo, Z. Tags: Animal Models of Human Disease, Cell Signaling/Signal Transduction, Cerebrovascular Disease/Stroke Basic Sciences Source Type: research