MST1 Suppression Reduces Early Brain Injury by Inhibiting the NF- κB/MMP-9 Pathway after Subarachnoid Hemorrhage in Mice.

Conclusions: The current findings indicate that MST1 participates in SAH-induced BBB disruption and white matter fiber damage via the downstream NF-κB-MMP-9 signaling pathway. Therefore, MST1 antagonists may serve as a novel therapeutic target to prevent early brain injury in SAH patients. PMID: 30018671 [PubMed - in process]
Source: Behavioural Neurology - Category: Neurology Authors: Tags: Behav Neurol Source Type: research

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BEST supplements for cholesterol: Too much cholesterol in the blood can lead to serious health problems in the future, including heart attacks and strokes. Anyone can have high cholesterol, but what is the best supplement to take to help lower it?
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Condition:   Stroke Intervention:   Device: Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) + Task Specifc Training Sponsors:   Medical University of South Carolina;   National Institutes of Health (NIH);   National Institute of General Medical Sciences (NIGMS) Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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