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Total 459 results found since Jan 2013.

Incidence of cardiometabolic outcomes among people living with HIV-1 initiated on integrase strand transfer inhibitor versus non-integrase strand transfer inhibitor antiretroviral therapies: a retrospective analysis of insurance claims in the United States
CONCLUSIONS: Over a short average follow-up period of <2 years, INSTI use among treatment-naïve PLWH was associated with an increased risk of several cardiometabolic outcomes, such as CHF, myocardial infarction and lipid disorders, compared to non-INSTI use. Further research accounting for additional potential confounders and with longer follow-up is warranted to more accurately and precisely quantify the impact of INSTI-containing ART on long-term cardiometabolic outcomes.PMID:37306118 | PMC:PMC10258864 | DOI:10.1002/jia2.26123
Source: Journal of the International AIDS Society - June 12, 2023 Category: Infectious Diseases Authors: Peter F Rebeiro Bruno Emond Carmine Rossi Brahim K Bookhart Aditi Shah Gabrielle Caron-Lapointe Marie-H élène Lafeuille Prina Donga Source Type: research

New Urban Health ‘Accelerator’ Aims to Transform Cardiovascular Population Health Globally
ihadmin2May 22, 2023May 22, 2023GenevaThe CARDIO4Cities Accelerator by Novartis Foundation and IntraHealth International aims to replicate the successful CARDIO4Cities approach in 30 major cities within three years to transform cardiovascular population health and equity globally.Results of initial programs in S ão Paulo, Dakar and Ulaanbaatar show the cost-effective approach averted up to 13% of strokes and 12% of heart attacks during implementation.Experts say public-private partnerships are key to address the growing burden of cardiovascular disease, the world ’s leading cause of death,according to the World Health O...
Source: IntraHealth International - May 22, 2023 Category: International Medicine & Public Health Authors: ihadmin2 Source Type: news

Prognostic implications of the 4S-AF scheme to characterize new-onset atrial fibrillation after myocardial infarction
CONCLUSIONS: Characterization of NOAF using the 4S-AF scheme aids in the risk stratification of AMI patients with NOAF.PMID:37037721 | DOI:10.1016/j.ejim.2023.04.003
Source: European Journal of Internal Medicine - April 10, 2023 Category: Internal Medicine Authors: Jiachen Luo Zhiqiang Li Xiaoming Qin Xingxu Zhang Xiangdong Liu Wenming Zhang Wei Xu Yiwei Zhang Yuan Fang Baoxin Liu Yidong Wei NOAFCAMI-SH Registry Investigators Source Type: research

Unmet Need for Sexual Rehabilitation after Acquired Brain Injury (ABI): A Cross-Sectional Study Concerning Sexual Activity, Sexual Relationships, and Sexual Rehabilitation after ABI
This study aims to explore experiences after non-stroke ABI concerning individual and relational aspects of sexuality, received information about sexuality at rehabilitation, and gender differences. A postal nationwide survey was conducted in Sweden, 2018 –2019. The sample included individuals who had participated in brain injury rehabilitation 2014–2016, response rate 40% (250/624). Among all participants 78% had resumed sexual activity, and there was a significant difference between males (84%, 118/140) and females (69%, 76/110,p = 0.004). Among all participants, 95% reported physical intimacy as important, 80% c...
Source: Sexuality and Disability - April 3, 2023 Category: Disability Source Type: research

Heart failure with reduced ejection fraction and atrial fibrillation: a Sub ‐Saharan African perspective
AbstractCardiovascular diseases are a well-established cause of death in high-income countries. In the last 20  years, Sub-Saharan Africa (SSA) has seen one of the sharpest increases in cardiovascular disease-related mortality, superseding that of infectious diseases, including HIV/AIDS, in South Africa. This increase is evidenced by a growing burden of heart failure and atrial fibrillation (AF) risk factor s. AF is a common comorbidity of heart failure with reduced ejection fraction (HFrEF), which predisposes to an increased risk of stroke, rehospitalizations, and mortality compared with patients in sinus rhythm. AF had ...
Source: ESC Heart Failure - March 20, 2023 Category: Cardiology Authors: Nonkanyiso Mboweni, Muzi Maseko, Nqoba Tsabedze Tags: Review Source Type: research

HIV Treatment and Neurologic Data Highlights From CROI 2023 HIV Treatment and Neurologic Data Highlights From CROI 2023
Highlights in HIV treatment from CROI 2023 focus on injectable and second-line therapies. Top neurologic data include risk factors for stroke and effect of HIV therapy on neurocognitive performance.Medscape
Source: Medscape Hiv-Aids Headlines - March 13, 2023 Category: Infectious Diseases Tags: HIV/AIDS ReCAP Source Type: news

Contrast-enhanced conebeam CT shows promise for breast biopsy
Contrast-enhanced conebeam CT imaging could serve as an alternative to MRI guidanc...Read more on AuntMinnie.comRelated Reading: CBCT reveals how 17th-century aristocrat sought to preserve her smile Can machine learning plus CBCT predict blood leaks in stroke patients? 3D image guidance enhances biopsy of peripheral lung nodules Conebeam CT aids removal of rare ectopic molar in maxillary sinus Can AI enhance the utility of breast conebeam CT?
Source: AuntMinnie.com Headlines - March 2, 2023 Category: Radiology Source Type: news

Molecules, Vol. 28, Pages 1021: Cyclic Glycine-Proline (cGP) Normalises Insulin-Like Growth Factor-1 (IGF-1) Function: Clinical Significance in the Ageing Brain and in Age-Related Neurological Conditions
ep Singh-Mallah Insulin-like growth factor-1 (IGF-1) function declines with age and is associated with brain ageing and the progression of age-related neurological conditions. The reversible binding of IGF-1 to IGF binding protein (IGFBP)-3 regulates the amount of bioavailable, functional IGF-1 in circulation. Cyclic glycine-proline (cGP), a metabolite from the binding site of IGF-1, retains its affinity for IGFBP-3 and competes against IGF-1 for IGFBP-3 binding. Thus, cGP and IGFBP-3 collectively regulate the bioavailability of IGF-1. The molar ratio of cGP/IGF-1 represents the amount of bioavailable and functional IG...
Source: Molecules - January 19, 2023 Category: Chemistry Authors: Jian Guan Fengxia Li Dali Kang Tim Anderson Toni Pitcher John Dalrymple-Alford Paul Shorten Gagandeep Singh-Mallah Tags: Review Source Type: research

Does higher knee hyperextension in patients with hemiplegia affect lateral and medial meniscus volume in the paretic leg? A cross-sectional study
ConclusionsThe knee hyperextension could not be ignored by physicians and needed to be diagnosed and treated as early as possible, the time since hemiplegia could be an indicator of sign of knee hyperextension.
Source: BMC Sports Science, Medicine and Rehabilitation - January 5, 2023 Category: Sports Medicine Source Type: research