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Infectious Disease: Hepatitis

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Total 168 results found since Jan 2013.

Atherosclerosis on CT coronary angiography and risk of long-term cardiovascular events post liver transplantation
CONCLUSION: The standardized CAD-RADS classification on CTCA predicted the occurrence of cardiovascular outcomes following LT, with a potential to increase utilization of preventive cardiovascular therapies.PMID:37432891 | DOI:10.1097/LVT.0000000000000215
Source: Atherosclerosis - July 11, 2023 Category: Cardiology Authors: Thalys Sampaio Rodrigues Anoop N Koshy Paul J Gow Laurence Weinberg Benjamin Cailes Adam Testro Gerard Smith Han S Lim Andrew W Teh Ruth P Lim Omar Farouque Source Type: research

Interaction between SIRT1 and non-coding RNAs in different disorders
SIRT1 is a member of the sirtuin family functioning in the process of removal of acetyl groups from different proteins. This protein has several biological functions and is involved in the pathogenesis of metabolic diseases, malignancy, aging, neurodegenerative disorders and inflammation. Several long non-coding RNAs (lncRNAs), microRNAs (miRNAs) and circular RNAs (circRNAs) have been found to interact with SIRT1. These interactions have been assessed in the contexts of sepsis, cardiomyopathy, heart failure, non-alcoholic fatty liver disease, chronic hepatitis, cardiac fibrosis, myocardial ischemia/reperfusion injury, diab...
Source: Frontiers in Genetics - June 27, 2023 Category: Genetics & Stem Cells Source Type: research

Estimate of the prevalence of subjects with chronic diseases in a province of Northern Italy: a retrospective study based on administrative databases
Conclusions Despite the difficulty of having a unique definition of chronic disease, the prevalence obtained was coherent with the estimates reported by other national surveillance systems such as Passi and Passi d’Argento. Underestimates were observed when international comparisons were done; however, when we used less stringent definitions of chronic diseases, similar results were obtained.
Source: BMJ Open - June 19, 2023 Category: General Medicine Authors: Airoldi, C., Pagnoni, F., Cena, T., Ceriotti, D., De Ambrosi, D., De Vito, M., Faggiano, F. Tags: Open access, Public health Source Type: research

Understanding HAT1: A Comprehensive Review of Noncanonical Roles and Connection with Disease
Genes (Basel). 2023 Apr 14;14(4):915. doi: 10.3390/genes14040915.ABSTRACTHistone acetylation plays a vital role in organizing chromatin, regulating gene expression and controlling the cell cycle. The first histone acetyltransferase to be identified was histone acetyltransferase 1 (HAT1), but it remains one of the least understood acetyltransferases. HAT1 catalyzes the acetylation of newly synthesized H4 and, to a lesser extent, H2A in the cytoplasm. However, 20 min after assembly, histones lose acetylation marks. Moreover, new noncanonical functions have been described for HAT1, revealing its complexity and complicating th...
Source: Atherosclerosis - April 28, 2023 Category: Cardiology Authors: Miguel A Ortega Diego De Leon-Oliva Cielo Garcia-Montero Oscar Fraile-Martinez Diego Liviu Boaru Mar ía Del Val Toledo Lobo Ignacio Garc ía-Tuñón Mar Royuela Natalio Garc ía-Honduvilla Julia Bujan Luis G Guijarro Melchor Alvarez-Mon Miguel Ángel Alv Source Type: research

Genes, Vol. 14, Pages 915: Understanding HAT1: A Comprehensive Review of Noncanonical Roles and Connection with Disease
-Mon Miguel Ángel Alvarez-Mon Histone acetylation plays a vital role in organizing chromatin, regulating gene expression and controlling the cell cycle. The first histone acetyltransferase to be identified was histone acetyltransferase 1 (HAT1), but it remains one of the least understood acetyltransferases. HAT1 catalyzes the acetylation of newly synthesized H4 and, to a lesser extent, H2A in the cytoplasm. However, 20 min after assembly, histones lose acetylation marks. Moreover, new noncanonical functions have been described for HAT1, revealing its complexity and complicating the understanding of its functions. Re...
Source: Genes - April 14, 2023 Category: Genetics & Stem Cells Authors: Miguel A. Ortega Diego De Leon-Oliva Cielo Garcia-Montero Oscar Fraile-Martinez Diego Liviu Boaru Mar ía del Val Toledo Lobo Ignacio Garc ía-Tuñón Mar Royuela Natalio Garc ía-Honduvilla Julia Bujan Luis G. Guijarro Melchor Alvarez-Mon Miguel Ángel A Tags: Review Source Type: research

Child-Pugh Class B or C Liver Disease Increases the Risk of Early Mortality in Patients With Hepatitis C Undergoing Elective Total Joint Arthroplasty Regardless of Treatment Status
CONCLUSION: Patients with HCV and a Child-Pugh Class B or C at the time of elective TJA had substantially increased odds of death, regardless of liver function, cirrhosis, age, Model for End-Stage Liver Disease level, HCV treatment, and viral load status. This is similar to the risk of early mortality observed in patients with chronic liver disease undergoing abdominal and cardiac surgery. Surgeons should avoid these major elective procedures in patients with Child-Pugh Class B or C whenever possible. For patients who feel their arthritic symptoms and pain are unbearable, surgeons need to be clear that the risk of death is...
Source: Clinical Orthopaedics and Related Research - March 24, 2023 Category: Orthopaedics Authors: Kyle H Cichos Eric Jordan Kian Niknam Antonia F Chen Erik N Hansen Gerald McGwin Elie S Ghanem Source Type: research

Preparation and optimization of surface stabilized cryptotanshinone nanocrystals with enhanced bioavailability
In conclusion, the results of this study suggest a feasible formulation for the oral delivery of CTS.
Source: Frontiers in Pharmacology - February 3, 2023 Category: Drugs & Pharmacology Source Type: research

From self-care behaviours to cardiometabolic risks prevention for the health of farmers: Nursing implications
CONCLUSION: The farmers in this study had a high prevalence of cardiometabolic risks, a high probability of stroke, inadequate number of remaining teeth and poor oral hygiene behaviours. These findings can provide evidence to develop health promotion programmes for farmers.IMPACT: This study demonstrates the health needs of farmers. We strongly recommend that community nurses empower farmers to engage in self-care behaviours through tailored health promotion programmes. For instance, by discussing cardiometabolic risk prevention from the farmers' perspectives to improve their health literacy.PMID:36695405 | DOI:10.1111/jan.15571
Source: Adv Data - January 25, 2023 Category: Epidemiology Authors: Yu-Ting Huang Ming-Shyan Lin Kathy James Chia-Hao Chang Wen-Hsuen Tsai Yu-Chih Lin Mei-Yen Chen Source Type: research

Exploring Stroke Risk Factors and Outcomes in Sexual and Gender Minority People
Discussion SGM people may have different risk factors, different mechanisms of stroke, and higher risk of recurrent stroke compared with non-SGM people. Standardized collection of sexual orientation and gender identity would enable larger studies to further understand disparities, leading to secondary prevention strategies.
Source: Neurology Clinical Practice - January 18, 2023 Category: Neurology Authors: Diaz, M. A., Rosendale, N. Tags: Research Article Source Type: research

Mr. M
Dr. Migliore I step off the subway, up the elevator, and up several flights of stairs. There’s a homeless man there who always uses the last stair of the lower staircase as a tray for his food. And by tray, I mean he sets his half-eaten rice burrito directly onto the step and picks around at it while I imagine the guacamole is mixing with Hep B and C. diff and MRSA. He looks up at me, I promise myself for the 100th time I’m going to start carrying cash or Kind bars or something; I give him my best sheepish face, and emerge at street level. I walk toward my hospital and pass a gentleman who sits on a ledge next to the ...
Source: The Hospitalist - December 1, 2022 Category: Hospital Management Authors: Lisa Casinger Tags: Essay Source Type: research

Research progress on Mincle as a multifunctional receptor
This article will review the various functions of Mincle, such as mediating sterile inflammation of tissues to accelerate disease progression, initiating immune responses to fight infection and promoting tumor progression.PMID:36436471 | DOI:10.1016/j.intimp.2022.109467
Source: International Immunopharmacology - November 27, 2022 Category: Allergy & Immunology Authors: Xinliang Huang Qinwei Yu Luyong Zhang Zhenzhou Jiang Source Type: research