Filtered By:
Infectious Disease: Malaria

This page shows you your search results in order of date. This is page number 10.

Order by Relevance | Date

Total 148 results found since Jan 2013.

ADAMTS13 and von Willebrand Factor in Thrombotic Thrombocytopenic Purpura.
Abstract Pathogenesis of thrombotic thrombocytopenic purpura (TTP) was a mystery for over half a century until the discovery of ADAMTS13. ADAMTS13 is primarily synthesized in the liver, and its main function is to cleave von Willebrand factor (VWF) anchored on the endothelial surface, in circulation, and at the sites of vascular injury. Deficiency of plasma ADAMTS13 activity (<10%) resulting from mutations of the ADAMTS13 gene or autoantibodies against ADAMTS13 causes hereditary or acquired (idiopathic) TTP. ADAMTS13 activity is usually normal or modestly reduced (>20%) in other forms of thrombotic microangi...
Source: Annual Review of Medicine - January 14, 2015 Category: Journals (General) Authors: Zheng XL Tags: Annu Rev Med Source Type: research

High Plasma Erythropoietin Levels are Associated With Prolonged Coma Duration and Increased Mortality in Children With Cerebral Malaria
Conclusions. High endogenous plasma EPO levels are associated with prolonged coma duration and increased mortality in children >18 months of age with CM.
Source: Clinical Infectious Diseases - December 12, 2014 Category: Infectious Diseases Authors: Shabani, E., Opoka, R. O., Idro, R., Schmidt, R., Park, G. S., Bangirana, P., Vercellotti, G. M., Hodges, J. S., Widness, J. A., John, C. C. Tags: ARTICLES AND COMMENTARIES Source Type: research

Clinical Associations of Cerebral Microbleeds on Magnetic Resonance Neuroimaging
Susceptibility-weighted and gradient-recalled echo T2* magnetic resonance imaging have enabled the detection of very small foci of blood within the brain, which have been termed “cerebral microbleeds.” These petechial intraparenchymal hemorrhages have begun to emerge as diagnostically and prognostically useful markers in a variety of disease states. Severe hypertension and cerebral amyloid angiopathy are perhaps the best established microhemorrhagic conditions from neuroimaging literature; however, many others are also recognized including cerebral autosomal dominant arteriopathy, subcortical infarcts, and leukoencepha...
Source: Journal of Stroke and Cerebrovascular Diseases - October 4, 2014 Category: Neurology Authors: Matthew Schrag, David M. Greer Tags: Review Article Source Type: research

The global burden of neurologic diseases
WHO categorizes causes of death and disability into (1) communicable diseases, maternal and perinatal conditions, and nutritional deficiencies; (2) non-communicable diseases (NCD); and (3) injuries. NCD are the leading cause of death and disability globally and are rising as a result of demographic and epidemiologic changes occurring in both developed and developing countries.1,2 Increasing life expectancies, unhealthy diet, physical inactivity, tobacco use, and harmful use of alcohol contribute to the growing incidence and prevalence of NCD, such as heart disease, stroke, diabetes, cancers, and chronic respiratory disease...
Source: Neurology - July 21, 2014 Category: Neurology Authors: Chin, J. H., Vora, N. Tags: All Cerebrovascular disease/Stroke, All epidemiology, All Epilepsy/Seizures GLOBAL PERSPECTIVES Source Type: research

Here Are the Real Victims of Pakistan’s War on the Taliban
An elderly displaced man carries a sack of rations on his shoulder. The Pakistan Army has distributed 30,000 ration packs of 110 kg each. Credit: Ashfaq Yusufzai/IPSBy Ashfaq YusufzaiPESHAWAR, Pakistan, Jul 1 2014 (IPS) Three days ago, Rameela Bibi was the mother of a month-old baby boy. He died in her arms on Jun. 28, of a chest infection that he contracted when the family fled their home in Pakistan’s North Waziristan Agency, where a full-scale military offensive against the Taliban has forced nearly half a million people to flee. Weeping uncontrollable, Bibi struggles to recount her story. “My son was born on Jul. 2...
Source: IPS Inter Press Service - Health - July 1, 2014 Category: Global & Universal Authors: Ashfaq Yusufzai Tags: Aid Armed Conflicts Asia-Pacific Development & Aid Economy & Trade Editors' Choice Environment Featured Food & Agriculture Gender Headlines Health Human Rights Humanitarian Emergencies Migration & Refugees Population Povert Source Type: news

Development of a Functional Scale for Progressive Multifocal Leukoencephalopathy: The NIH PML Scale (S10.005)
CONCLUSIONS: The NIH-PML scale provides a comprehensive functional assessment of the neurological status of this patient population. A specific clinical scale for PML will be important when evaluating future treatment strategies.Disclosure: Dr. Von Geldern has nothing to disclose. Dr. Cortese has nothing to disclose. Dr. Reich has nothing to disclose. Dr. Nath has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Von Geldern, G., Cortese, I., Ohayon, J., Reich, D., Nath, A. Tags: HIV, PML, and Cerebral Malaria Source Type: research

Neuregulin-1 attenuates mortality associated with experimental cerebral malaria
Conclusions: This study suggests that NRG-1 attenuates ECM-associated brain inflammation and injuries and may represent a novel supportive therapy for the management of CM.
Source: Epidemiologic Perspectives and Innovations - January 17, 2014 Category: Epidemiology Authors: Wesley SolomonNana O WilsonLeonard AndersonSidney PittsJohn PatricksonMingli LiuByron D FordJonathan K Stiles Source Type: research

Neurocognitive sequelae following hippocampal and callosal lesions associated with cerebral malaria in an immune-naive adult
We report a case of a 36-year-old immune-naive Caucasian female who sustained a brain injury with neurocognitive sequelae, after a severe bout of falciparum malaria. On admission, she was unconscious, febrile, hypoglycaemic and passing black urine. She had returned from Ghana 2 days earlier. Her initial parasite count was 22%,...
Source: Postgraduate Medical Journal - October 15, 2013 Category: Journals (General) Authors: Laverse, E., Nashef, L., Brown, S. Tags: Immunology (including allergy), Drugs: infectious diseases, Travel medicine, Tropical medicine (infectious diseases), Epilepsy and seizures, Stroke, Memory disorders (psychiatry), Adult intensive care, Epidemiology, Diabetes, Metabolic disorders Images Source Type: research

Australia faces increased risk of disease from climate change, reports find
A number of recent studies have shown a clear connection between a warming planet and increased health risksAustralia has been warned of the rising threat of dengue fever and heat stroke deaths in the wake of a study that found climate change is aiding the spread of infectious diseases around the world. The report, part-funded by the US National Science Foundation and published in Science, found that climate change is already abetting diseases in wildlife and agriculture, with humans at heightened risk from dengue fever, malaria and cholera. Wealthy countries will do much better at predicting and tackling new disease threa...
Source: Guardian Unlimited Science - August 2, 2013 Category: Science Authors: Oliver Milman Tags: theguardian.com News Climate change Environment Australia Source Type: news

Stroke in sickle cell anemia patients: A need for multidisciplinary approaches
Abstract: Sickle cell anemia (SCA) is an autosomal recessive disorder, with Mendelian inheritance pattern, caused by a missense mutation in the β-polypeptide chain of the hemoglobin B. SCA preferentially affects populations in countries where malaria was/is present (e.g. Africa, USA, Brazil). Thereby, in USA, the incidence of SCA is relatively high, around 1/500, and the prevalence is about 1/1000. In Brazil, SCA represents a major public health problem with an incidence ranging from 1/2000 to 1/600 depending on the regions. Homozygotic patients present more severe medical conditions and reduced life expectancy than heter...
Source: Atherosclerosis - June 10, 2013 Category: Cardiology Authors: Farid Menaa Tags: Reviews Source Type: research

Albumin: Pathophysiologic basis of its role in the treatment of cirrhosis and its complications
Abstract Since the introduction of human serum albumin as a plasma expander in the 1940s, considerable research has allowed a better understanding of its biochemical properties and potential clinical benefits. Albumin has a complex structure, which is responsible for a variety of biological functions. In disease, albumin molecule is susceptible to modifications that may alter its biological activity. During the last decades, different methods to measure albumin function have been developed. Recent studies have shown that not only albumin concentration but also albumin function is reduced in liver failure. This observation ...
Source: Hepatology - February 19, 2013 Category: Internal Medicine Authors: Rita Garcia‐Martinez, Paolo Caraceni, Mauro Bernardi, Pere Gines, Vicente Arroyo, Rajiv Jalan Tags: Liver Failure, Cirrhosis and Portal Hypertension Source Type: research

Nitrone-based Therapeutics for Neurodegenerative Diseases. Their use alone or in Combination with Lanthionines.
Abstract The possibility of free radical reactions occurring in biological processes led to the development and employment of novel methods and techniques focused on determining their existence and importance in normal and pathological conditions. For this reason the use of Nitrones for spin trapping free radicals came into widespread use in the 1970s and 1980s when surprisingly the first evidence of their potent biological properties was first noted. Since then wide-spread exploration and demonstration of the potent biological properties of phenyl-tert-butylnitrone (PBN) and derivatives were shown in preclinical ...
Source: Free Radical Biology and Medicine - February 15, 2013 Category: Biology Authors: Floyd RA, Castro Faria Neto HC, Zimmerman GA, Hensley K, Towner RA Tags: Free Radic Biol Med Source Type: research

KCA Board Member to Participate in LIVESTRONG ® Global Cancer Summit in Dublin, Ireland
                                                                                      FOR IMMEDIATE RELEASE   Kidney Cancer Association CONTACT NAME: Carrie Konosky PHONE NUMBER: 847-655-4495 x104 EMAIL ADDRESS: ckonosky@kidneycancer.org   Eric Perakslis, Kidney Cancer Association Board Member, Selected to Participate in Premiere LIVE ST...
Source: Kidney Cancer Association - July 17, 2009 Category: Urology & Nephrology Source Type: news