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Infectious Disease: Zika Virus
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Total 24 results found since Jan 2013.
New spectrum of the neurologic consequences of Zika
Zika virus infection represents a new neuropathological agent with association to a wide spectrum of neurological complications: a) Congenital Zika Syndrome by affecting the neural stem cells of the human fetal brain; b) Guillain-Barr é Syndrome by an autoimmune response against peripheral myelin and/or axonal components or probable direct inflammatory reaction; c) Encephalitis/meningoencephalitis and myelitis by a direct viral inflammatory process on the central nervous system; d) Sensory neuropathy by infecting directly the pe ripheral neurons and causing substantial cell death and pathogenic transcriptional dysregulati...
Source: Journal of the Neurological Sciences - October 31, 2017 Category: Neurology Authors: Marco T. Medina, Marco Medina-Montoya Tags: Editorial Source Type: research
ZIKA vasculitis: A new cause of stroke in children?
Viral infectious vasculitis is a cause of stroke in children. Zika virus infection is often asymptomatic. Neurological complications have however been reported: Guillain-Barr é, ADEM, meningoencephalitis, myelitis, microcephaly in the fetus of infected mothers. We discuss the case of a child presenting acute infection with ZIKV that was associated with a stroke. A 10-months-old boy without medical history presented after 2days of fever and cutaneous rash, conjunctivitis on day 5, a right hemiparesis on day 6.
Source: Journal of the Neurological Sciences - October 27, 2017 Category: Neurology Authors: Anne Landais, Audrey C ésaire, Manuel Fernandez, Sébastien Breurec, Cécile Herrmann, Fréderique Delion, Philippe Desprez Tags: Letter to the Editor Source Type: research
What Causes Microcephaly?
Discussion
Microcephaly is usually defined as an occipitofrontal head circumference (OFC) more than 2 standard deviations (SD) below the mean for sex, age and ethnicity. Severe microcephaly is used for OFC < 3 standard deviations. Rates of microcephaly range from 0.5-12 patients/10,000 live births.
The OFC should be measured at every well child visit and at other opportunities and plotted on standard growth charts. The OFC is measured using a nonelastic tape measure around the largest part of the head with the tape measure held above the eyebrows and ears. It is a highly reproducible measurement. There are several diff...
Source: PediatricEducation.org - September 25, 2017 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news
Hopkins Nursing—Dean on Chronic Disease / Pediatrics
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Source: Johns Hopkins University and Health Systems Archive - July 27, 2017 Category: Nursing Source Type: news
Zika associated Guillain-Barre syndrome in the United States (P2.327)
Conclusions:Zika can induce GBS after a brief viral illness. Neuropathy can be a mixture of demyelinating and axonal. Dysautonomia may also be present including severe dysphagia, orthostatics and retention.Zika RNA has a short detection window in serum and CSF making a diagnosis time sensitive. Serological assays using IgM and IgG cross-react with other flaviviruses making them unable to differentiate between recent Zika exposure and cross reactivity with Dengue and Chikungunya. Our pt likely had prior exposure to Dengue, being from an endemic area. Prior Dengue exposure may possibly modulate the response to Zika via antib...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Tantillo, G., Sclar, G., Vasa, C., Shin, S., Sivak, M. Tags: Zika, Chikungunya, West Nile Virus, and Other Viral Infections I Source Type: research
Neurological involvement in Chikangunya Virus infection (S40.007)
Conclusions:Chikangunya fever is frequently associated with neurological symptoms, especially alteration in sensorium, neutrophilia and hyponatremia in more than two-thirds of the patients, sepsis and hepatorenal dysfunction in almost one third of the patients, CSF lymphocytosis with raised proteins and topographically involves temporal and frontal lobes predominantly.Disclosure: Dr. Anand has nothing to disclose. Dr. Kasundra has nothing to disclose. Dr. Prasad has nothing to disclose. Dr. Handa has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Anand, R., Kasundra, G., Prasad, A., Handa, R. Tags: Infectious Disease: The Neurology of Zika, Chikungunya, and Acute Flaccid Myelitis Source Type: research
December blogs digest: the health benefits of nuts, sequencing the Iberian lynx genome, the importance of pets and more
How can we measure health behavior theories mathematically?
William Riley looks at whether Social Cognitive Theory (SCT) could be expressed mathematically. He reports on his article published in Translational Behavioral Medicine in which he and co-authors developed a dynamic computational model for SCT.
Magnesium deficiency and its multiple health outcomes
Getting enough magnesium in your diet? A study published in BMC Medicine last month found that increased dietary magnesium is associated with a reduced risk of heart failure, stroke, diabetes, and all-cause mortality. The study was the largest of its kind to date, using ...
Source: BioMed Central Blog - January 6, 2017 Category: Journals (General) Authors: Davy Falkner Tags: Biology Health Medicine Open Access blogs digest Source Type: blogs
Identification and genetic characterization of Zika virus isolated from an imported case in China.
In this study, we reported the complete genomic sequence of Zika virus strain ZKC2/2016 from an imported case in China, in February 2016. The virus was isolated and virus characteristics were identified by cytopathic effect, quantitative real time-PCR, immunofluorescence assay and electronic microscopy. Next generation sequencing (NGS) technique and 5' and 3' Rapid Amplification cDNA Ends (RACE) PCR were used to sequence the complete genome. The genome length of this newly obtained Zika virus strain is 10,807base pairs (bp). Genetic analysis showed that ZKC2/2016, along with other Chinese Zika virus strains in 2016, formed...
Source: Infection, Genetics and Evolution - October 30, 2016 Category: Genetics & Stem Cells Authors: Liu L, Zhang S, Wu, Song J, Li A, Zhang H, Wu W, Tan Q, Li C, Zhang Q, Zhou H, Liang M, Ke C, Li D Tags: Infect Genet Evol Source Type: research
Zika Virus Emergence and Expansion: Lessons Learned from Dengue and Chikungunya May Not Provide All the Answers.
Abstract
Following the emergence of Zika in the past decade, there are lessons to be learned from similar emergence events of dengue (DENV) and chikungunya (CHIKV). Specifically, as Zika emerges in the Americas there is a natural tendency to apply the knowledge base of DENV and CHIKV to mitigation and control of a virus with such a similar transmission system. However, there are marked differences that may preclude such broad stroke application of this knowledge base without making potentially faulty assumptions. Herein, Zika virus (ZIKV) transmission is reviewed, and the commonalities among these three arboviruse...
Source: The American Journal of Tropical Medicine and Hygiene - February 22, 2016 Category: Tropical Medicine Authors: Christofferson RC Tags: Am J Trop Med Hyg Source Type: research
