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Melanocortin neurons: multiple routes to regulation of metabolism.
Abstract The burden of disability, premature death, escalating health care costs and lost economic productivity due to obesity and its associated complications including hypertension, stroke, cardiovascular disease and type 2 diabetes is staggering [1, 2]. A better understanding of metabolic homeostatic pathways will provide us with insights into the biological mechanisms of obesity and how to fundamentally address this epidemic [3-6]. In mammals, energy balance is maintained via a homeostatic system involving both peripheral and central melanocortin systems; changes in body weight reflect an unbalance of the ener...
Source: Biochimica et Biophysica Acta - May 9, 2017 Category: Biochemistry Authors: Shen WJ, Yao T, Kong X, Williams KW, Liu T Tags: Biochim Biophys Acta Source Type: research

Achieving better detection of vascular risk factors for stroke prevention (P4.062)
Conclusions:The concept of vital station is a useful means of detecting vascular risk factor before appearance of noticeable symptoms and thus offers the benefit of being able to treat the disease much earlier which can lead to reduction of disease burden & economic losses and thus offers better health outcome.Disclosure: Dr. Mehndiratta has nothing to disclose. Dr. Wadhai has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Mehndiratta, M. M., Wadhai, S. Tags: General Neurology: Vascular Neurology Source Type: research

Women ’s Health Policies Should Focus on NCDs
Professor Robyn Norton, co-founder and Principal Director of the George Institute for Global Health. Credit: Neena Bhandari/IPSBy Neena BhandariSYDNEY, Apr 11 2017 (IPS)Science and medicine were not subjects of dinnertime conversations in the Norton household in Christchurch, New Zealand, but Professor Robyn Norton grew up observing her parents’ commitment to equity and social justice in improving people’s lives. It left an indelible impression on her young mind.Her high school years coincided with the women’s movement reaching its peak. She got drawn into thinking about addressing women’s health issues and moved t...
Source: IPS Inter Press Service - Health - April 11, 2017 Category: Global & Universal Authors: Neena Bhandari Tags: Asia-Pacific Featured Global Headlines Health Poverty & SDGs Women's Health Non-communicable Diseases (NCDs) Source Type: news

Why should we screen for atrial fibrillation?
Atrial fibrillation (AF) constitutes an increasing challenge to the medical community and healthcare providers. With a prevalence of almost 3% in the adult Swedish population1 and a forecasted twofold or threefold increase by 2050 in the USA, we are facing a diagnosis with epidemic proportions. Apart from increased mortality, AF also increases the risk of heart failure, hospitalisations and ischaemic stroke.2 Of these complications, ischaemic stroke gives a particularly heavy burden on patients, their family and society. Ischaemic stroke is the most common reason for permanent neurological disability in the adult Western p...
Source: Heart - December 8, 2016 Category: Cardiology Authors: Svennberg, E., Engdahl, J. Tags: Press releases, Drugs: cardiovascular system, Epidemiology Editorials Source Type: research

UK heart disease and stroke death rates now lower than cancer
Conclusion This valuable research informs on the burden of cardiovascular disease and associated mortality across European countries. It demonstrates that CVD is still the most common cause of death across Europe, but rates have been falling over the past 10 years. This fall means that in several European countries, including the UK, cancer rates now overtake CVD death rates in men. Generally, CVD disability and burden of disease seems to be greater in Eastern European countries. The WHO mortality data and population data are quite up-to-date and should be reliable, though as the researchers say, there was a lack of high ...
Source: NHS News Feed - August 15, 2016 Category: Consumer Health News Tags: Heart/lungs Cancer Neurology Source Type: news

Tuberculosis Made Me Blind, But We Can Make Sure No One Else Needs to Suffer Like I Did
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Source: Healthy Living - The Huffington Post - March 24, 2016 Category: Consumer Health News Source Type: news

Environmental Pollution: An Under-recognized Threat to Children’s Health, Especially in Low- and Middle-Income Countries
Conclusions Patterns of disease are changing rapidly in LMICs. Pollution-related chronic diseases are becoming more common. This shift presents a particular problem for children, who are proportionately more heavily exposed than are adults to environmental pollutants and for whom these exposures are especially dangerous. Better quantification of environmental exposures and stepped-up efforts to understand how to prevent exposures that cause disease are needed in LMICs and around the globe. To confront the global problem of disease caused by pollution, improved programs of public health monitoring and environmental protecti...
Source: EHP Research - March 1, 2016 Category: Environmental Health Authors: Web Admin Tags: Brief Communication March 2016 Source Type: research

Obesity Statistics.
Abstract Obesity is a chronic disease that is strongly associated with an increase in mortality and morbidity including, certain types of cancer, cardiovascular disease, disability, diabetes mellitus, hypertension, osteoarthritis, and stroke. In adults, overweight is defined as a body mass index (BMI) of 25 kg/m(2) to 29 kg/m(2) and obesity as a BMI of greater than 30 kg/m(2). If current trends continue, it is estimated that, by the year 2030, 38% of the world's adult population will be overweight and another 20% obese. Significant global health strategies must reduce the morbidity and mortality associated with...
Source: Primary Care - February 21, 2016 Category: Primary Care Authors: Smith KB, Smith MS Tags: Prim Care Source Type: research

Obesity Statistics
Obesity is a chronic disease that is strongly associated with an increase in mortality and morbidity including, certain types of cancer, cardiovascular disease, disability, diabetes mellitus, hypertension, osteoarthritis, and stroke. In adults, overweight is defined as a body mass index (BMI) of 25 kg/m2 to 29 kg/m2 and obesity as a BMI of greater than 30 kg/m2. If current trends continue, it is estimated that, by the year 2030, 38% of the world’s adult population will be overweight and another 20% obese. Significant global health strategies must reduce the morbidity and mortality associated with the obesity epidemic.
Source: Primary Care: Clinics in Office Practice - January 12, 2016 Category: Primary Care Authors: Kristy Breuhl Smith, Michael Seth Smith Source Type: research

New journal JAMA Cardiology to debut in 2016
As cardiovascular disease remains the No. 1 cause of death and disability worldwide, a new medical journal will premiere early next year to serve the global cardiology community. JAMA Cardiology—to be led by an internationally renowned cardiologist—will premiere as the 12th journal in the JAMA Network, which includes JAMA and 10 other specialty journals. “The burden of hypertension, ischemic heart disease, heart failure, stroke, valvular heart disease and atrial fibrillation is reaching epidemic proportions worldwide,” writes Howard Bauchner, MD, editor in chief of The JAMA Network, and colleagues in a JAMA edito...
Source: AMA Wire - October 12, 2015 Category: Journals (General) Authors: Amy Farouk Source Type: news

JAMA Cardiology—A New JAMA Network Journal
Cardiovascular disease remains the leading cause of death and disability worldwide, in developed and developing countries. Despite the success in the last decade in reducing heart disease–related mortality in many countries, with aging of the population and persistent cardiovascular risk factors, the burden of hypertension, ischemic heart disease, heart failure, stroke, valvular heart disease, and atrial fibrillation is reaching epidemic proportions worldwide.
Source: JAMA - Journal of the American Medical Association - October 12, 2015 Category: Journals (General) Source Type: research

Effectiveness Of A Structured Teaching Programme In Improving The Knowledge And Skills Of The Care Givers And Preventing Secondary Complications In Hospitalized Stroke Patients (P5.147)
Conclusion: The structured teaching program was effective in improving the knowledge and skill of the caregivers and decreasing the complications in the hospitalized stroke patients.Disclosure: Dr. Bhatia has nothing to disclose. Dr. Thomas has nothing to disclose. Dr. Agarwal has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Bhatia, R., Thomas, A., Agarwal, M. Tags: Cerebrovascular Disease and Interventional Neurology: Quality Research and Initiatives Source Type: research

The burden of disease in older people and implications for health policy and practice
Publication date: 7–13 February 2015 Source:The Lancet, Volume 385, Issue 9967 Author(s): Martin J Prince , Fan Wu , Yanfei Guo , Luis M Gutierrez Robledo , Martin O'Donnell , Richard Sullivan , Salim Yusuf 23% of the total global burden of disease is attributable to disorders in people aged 60 years and older. Although the proportion of the burden arising from older people (≥60 years) is highest in high-income regions, disability-adjusted life years (DALYs) per head are 40% higher in low-income and middle-income regions, accounted for by the increased burden per head of population arising from cardiovascular disease...
Source: The Lancet - February 10, 2015 Category: Journals (General) Source Type: research

Facing the noncommunicable disease (NCD) global epidemic – The battle of prevention starts in utero – The FIGO challenge
Publication date: January 2015 Source:Best Practice & Research Clinical Obstetrics & Gynaecology, Volume 29, Issue 1 Author(s): Lluis Cabero Roura , Sir Sabaratnam Arulkumaran Noncommunicable diseases (NCDs) are responsible for 36 million deaths every year. Of this death toll, nearly 80% (29 million) occur in low- and median-income countries. More than 9 million deaths attributed to NCDs occur in people under 60 years of age. National economies are suffering considerable losses due to premature death or disability to work resulting from heart disease, stroke, and diabetes. The knowledge that in utero and ...
Source: Best Practice and Research Clinical Obstetrics and Gynaecology - January 24, 2015 Category: OBGYN Source Type: research

Prevention Science Should Be a Higher Federal Funding Priority
This study highlights inadequate investment of federal funding for science that will help us better prevent chronic disease. Investing in prevention -- and prevention science -- should become a much higher priority for federal research. It's essential if the United States is to improve the health of our population and save future generations of Americans from the burden of preventable disease.
Source: Healthy Living - The Huffington Post - January 7, 2015 Category: Consumer Health News Source Type: news

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