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Infectious Disease: Tuberculosis

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Total 231 results found since Jan 2013.

Medical knowledge level of Roma inmantes
Conclusions. We have noticed that a great part of the subjects did not have basic medical knowledge. We can say that the level of tuition has a direct impact on FEV1. The primary care physician can potentially improve patient outcomes by increasing medical education level, including the recognition of exacerbation, risk factors, signs and symptoms. The format for the delivery of education will vary depending on staff availability and expertise.
Source: European Respiratory Journal - December 23, 2014 Category: Respiratory Medicine Authors: Oancea, C., Fira-Mladinescu, O., Marc, M., Decun, C., Iovan, I., Stoia, E., Crisan, A., Tudorache, V. Tags: 12.1 Medical Education, Web and Internet Source Type: research

ANCA associated vasculitis - Evaluation of diagnosis, treatment and outcome in a group of 68 patients
Conclusions: Significant differences exist between GPA and MPA at the initial presentation that can predict the evolution of the disease. The management of patients with ANCA-associated vasculitides is difficult and marked by the adverse effects of the therapy.
Source: European Respiratory Journal - December 23, 2014 Category: Respiratory Medicine Authors: Belaconi, I., Toma, C., Stancu, S., Dumitrache-Rujinski, S., Tudose, C., Croitoru, A., Grigoriu, L., Leonte, D., Magheran, E., Bogdan, M. Tags: 1.13 Clinical Problems - Other Source Type: research

Text alerts 'help prompt people to take their pills'
Conclusion This randomised study found a text messaging reminder service led to more people taking medication as prescribed. It appears this was because not taking the medication or not responding to the text led to a discussion with a healthcare professional, which influenced people to continue taking their medicines. The study was clearly reported and was of adequate size to find a difference between the two groups, if there was one. But, as with all studies, there are some limitations to consider. The results of the study may not be applicable to everyone. The recruitment process meant the participants were already ...
Source: NHS News Feed - December 8, 2014 Category: Consumer Health News Tags: Medical practice Medication Heart/lungs Source Type: news

Stroke in patients with tuberculous meningitis in a low TB endemic country: an increasing medical emergency?
This study evaluated the frequency, clinical characteristics, risk factors and outcomes of patients with TBM complicated by stroke admitted to the Infectious Disease Clinic, University of Perugia Hospital, Italy from 1971 to 2010. Over four decades, 419 patients were admitted with tuberculosis, of these 30 (7.1%) were diagnosed with TBM: 20 definite, one probable and nine possible. Twenty-six were evaluable for stroke and six (23%) had stroke. The latter six had advanced stages of meningitis, two tested HIV positive, three HIV negative and in one HIV was not performed. Of seven patients without stroke tested for HIV, only ...
Source: New Microbiologica - December 1, 2014 Category: Microbiology Tags: New Microbiol Source Type: research

Correlation between use of simvastatin and lovastatin and female lung cancer risk: a nationwide case-control study.
CONCLUSIONS: Simvastatin use at a DDD of more than 150 is correlated with an approximately 20% reduction in the risk of lung cancer in women. PMID: 25421876 [PubMed - as supplied by publisher]
Source: Clinical Lung Cancer - November 25, 2014 Category: Cancer & Oncology Authors: Yang TY, Lin WM, Lin CL, Sung FC, Kao CH Tags: Int J Clin Pract Source Type: research

Correlation between use of simvastatin and lovastatin and female lung cancer risk: a nationwide case–control study
ConclusionsSimvastatin use at a DDD of more than 150 is correlated with an approximately 20% reduction in the risk of lung cancer in women.
Source: International Journal of Clinical Practice - November 25, 2014 Category: Internal Medicine Authors: T.‐Y. Yang, W.‐M. Lin, C.‐L. Lin, F.‐C. Sung, C.‐H. Kao Tags: Original Paper Source Type: research

Pneumonia: When Antibiotics Are Not the Answer
We present the case of an 88-year-old bedridden man, with hypertension, multiple myeloma, coronary artery disease, ischemic stroke, seizures, dysphagia, and constipation under treatment with mineral oil. He was brought to the emergency department after 3 days of cough, dysphagia, and dyspnea, following a recent hospitalization, due to a health care–associated pneumonia. A chest computed tomography scan obtained showed bilateral multifocal opacities with consolidates described as Hounsfield units of −62, consistent with fat. A diagnosis of lipoid pneumonia was done, and mineral oil was discontinued. Given the patient’...
Source: Infectious Diseases in Clinical Practice - October 31, 2014 Category: Infectious Diseases Tags: Case Reports Source Type: research

Cerebral infarction and tuberculoma in central nervous system tuberculosis: frequency and prognostic implications
Conclusions Tuberculomas were present in 50% of patients, while infarcts were present in 25%. Old age, TBM grading, presence of infarction and hydrocephalus were all predictors of poor outcome.
Source: Journal of Neurology, Neurosurgery and Psychiatry - October 17, 2014 Category: Neurosurgery Authors: Wasay, M., Farooq, S., Khowaja, Z. A., Bawa, Z. A., Ali, S. M., Awan, S., Beg, M. A., Mehndiratta, M. M. Tags: Meningitis, Hydrocephalus, Infection (neurology), Stroke Neuroinfection Source Type: research

Endocardial tuberculosis.
We report a 30-year-old male patient with persistent fever, history of stroke, and a left atrial mass. He was diagnosed as miliary pulmonary tuberculosis radiologically and had fever despite 2 months of antitubercular treatment. The mass was excised and fever resolved. Acid fast bacilli (AFB) were demonstrable on Ziehl Neelsen stain and routine histopathology. To the best of our knowledge, the visualization of AFB from an intracardiac lesion on ZN staining has not been reported earlier and tuberculosis must be considered in the differential diagnosis of left atrial masses. PMID: 25282244 [PubMed - in process]
Source: The Annals of Thoracic Surgery - October 1, 2014 Category: Cardiovascular & Thoracic Surgery Authors: Kandachar P, Guin D, Mohanty S, Sinha N, George M, Nagaraj S, Fathima S, Lal N Tags: Ann Thorac Surg Source Type: research

The global burden of neurologic diseases
WHO categorizes causes of death and disability into (1) communicable diseases, maternal and perinatal conditions, and nutritional deficiencies; (2) non-communicable diseases (NCD); and (3) injuries. NCD are the leading cause of death and disability globally and are rising as a result of demographic and epidemiologic changes occurring in both developed and developing countries.1,2 Increasing life expectancies, unhealthy diet, physical inactivity, tobacco use, and harmful use of alcohol contribute to the growing incidence and prevalence of NCD, such as heart disease, stroke, diabetes, cancers, and chronic respiratory disease...
Source: Neurology - July 21, 2014 Category: Neurology Authors: Chin, J. H., Vora, N. Tags: All Cerebrovascular disease/Stroke, All epidemiology, All Epilepsy/Seizures GLOBAL PERSPECTIVES Source Type: research

Free‐floating thrombus in stroke patients with nonstenotic internal carotid artery—An ultrasonographic study
ConclusionsInternal carotid artery FFT could be found in young stroke patients without identifiable arterial disease and could be resolved with antithrombotic treatment © 2014 Wiley Periodicals, Inc. J Clin Ultrasound, 2014
Source: Journal of Clinical Ultrasound - June 4, 2014 Category: Radiology Authors: Evguenia Vassileva, Marin Daskalov, Paraskeva Stamenova Tags: Research Article Source Type: research

Spontaneous sternocleidomastoid muscle hematoma following thrombolysis for acute ischemic stroke
We report the case of an 83y.o. woman with right facio-brachio-crural hemiparesis, left deviation of the head and aphasia who developed, after thrombolytic therapy, a spontaneous sternocleidomastoid muscle hematoma that regressed few days later. To our knowledge, this is the first case reported in the literature of asymptomatic and spontaneous skeletal muscle hematoma following thrombolysis for the treatment of acute ischemic stroke. The occurrence of lateral cervical tuberculosis lymphadenitis ipsilateral to sternocleidomastoid muscle hematoma may suggest a causal relationship between local chronic inflammation of active ...
Source: Journal of the Neurological Sciences - April 28, 2014 Category: Neurology Authors: Nadia Mariagrazia Giannantoni, Giacomo Della Marca, Aldobrando Broccolini, Fabio Pilato, Paolo Profice, Roberta Morosetti, Pietro Caliandro, Giovanni Frisullo Tags: Letters to the Editor Source Type: research

Heart attack death rates halve from 2001-12 but cancer mortalities rise
But ONS mortality data for period show circulatory disease as overall top cause of deaths in England and WalesDeaths from heart attacks and stroke halved in England and Wales over the first 11 years of this century, while the numbers dying from cancer rose, according to newly published mortality data from the Office for National Statistics.The 21st century mortality files from the ONS contain a vast amount of data not only about the big killers of modern times but also the more surprising and less likely accidental causes of mortality.Only three people died from snake bites, all men, between 2001 and 2012. One man died of ...
Source: Guardian Unlimited Science - October 23, 2013 Category: Science Authors: Sarah Boseley Tags: Heart attack Nutrition theguardian.com Office for National Statistics News Health Government data Smoking Society Alzheimer's Cancer UK news Source Type: news

The role of 3-ketosteroid 1(2)-dehydrogenase in the pathogenicity of Mycobacterium tuberculosis
Conclusions: The Mtb mutant DeltakstD strain, which is unable to use cholesterol as a source of carbon and energy, has a limited ability to multiply in resting M[latin capital letter o with stroke] following infection, reflecting a failure of the DeltakstD strain to inhibit the TLR2-dependent bactericidal activity of resting M[latin capital letter o with stroke].
Source: BMC Microbiology - Latest articles - February 20, 2013 Category: Microbiology Authors: Marta BrzezinskaIzabela SzulcAnna BrzostekMagdalena KlinkMichal KielbikZofia SulowskaJakub PawelczykJaroslaw Dziadek Source Type: research

Stroke Drug Kills Bacteria That Cause Ulcers And Tuberculosis
A drug currently being used to treat ischemic strokes may prove to be a significant advance in the treatment of tuberculosis and ulcers. In a new research report appearing online in The FASEB Journal, a compound called ebselen effectively inhibits the thioredoxin reductase system in a wide variety of bacteria, including Helicobacter pylori which causes gastric ulcers and Mycobacterium tuberculosis which causes tuberculosis. Thioredoxin and thioredoxin reductase proteins are essential for bacteria to make new DNA, and protect them against oxidative stress caused by the immune system...
Source: Health News from Medical News Today - January 2, 2013 Category: Consumer Health News Tags: Tuberculosis Source Type: news