Filtered By:
Source: European Respiratory Journal
This page shows you your search results in order of date. This is page number 14.
Order by Relevance | Date
Total 303 results found since Jan 2013.
The effect of 6-mercaptopurine treatment on experimentally induced pulmonary arterial hypertension
Conclusion: 6-MP partly reversed RV systolic pressure and RV afterload in established PAH. Together with the observed improved RV remodeling and cardiac function, 6-MP may be a promising intervention for PAH.
Source: European Respiratory Journal - December 6, 2017 Category: Respiratory Medicine Authors: Sun, X.-Q., Kurakula, K., Happe, C., da Silva Goncalves Bos, D., Schalij, I., Vonk-Noordegraaf, A., de Man, F. S., Bogaard, H.-J., Goumans, M.-J. Tags: Pulmonary Circulation and Pulmonary Vascular Disease Source Type: research
Cardiovascular events and mortality in CPAP adherent OSAS patients - a 9-year retrospective study
Conclusions: High adherence to CPAP treatment protected OSAS patients against primary and secondary ischemic cardiovascular events and deaths.
Source: European Respiratory Journal - December 6, 2017 Category: Respiratory Medicine Authors: Myllylä, M., Hammais, A., Stepanov, M., Anttalainen, U., Saaresranta, T., Laitinen, T. Tags: Sleep and Control of Breathing Source Type: research
Management of hypertension in obstructive sleep apnoea: predicting blood pressure reduction under continuous positive airway pressure
Hypertension affects a quarter of the adult population and remains a leading cause of cardiovascular mortality, accounting for 13.5% of all deaths. Half of all strokes and ischaemic heart disease events are attributable to high blood pressure (BP) [1, 2]. Most patients exhibit Grade-I hypertension (systolic BP of 140 to 159 mmHg and/or diastolic BP of 90 to 99 mmHg) without co-existing cardiovascular disease. An active reduction of BP results in a significant reduction in stroke and death [3].
Source: European Respiratory Journal - October 5, 2017 Category: Respiratory Medicine Authors: Tamisier, R., Levy, P. Tags: Sleep medicine Editorial Source Type: research
Clinical screening of oropharyngeal dysphagia: standard of care
We read with interest the paper by Verin et al. [1] related to oropharyngeal dysphagia and its importance in institutionalised neurological and head and neck patients, between others. Furthermore, this is a very common problem in the critical and intermediate care settings, and a similar situation occurs with other acute neurological diseases, such as amyotrophic lateral sclerosis, cerebral trauma, post-neurosurgical procedures and toxic metabolic encephalopathies [2, 3]. The authors emphasised the necessity of identifying risks factors for aspiration early and suggested that clinical screening methods are needed to r...
Source: European Respiratory Journal - August 31, 2017 Category: Respiratory Medicine Authors: Caviedes, I., Fernandez-Bussy, S., Labarca, G., Herth, F. J. F. Tags: Respiratory clinical practice Original Articles: Correspondence Source Type: research
Concurrent use of long-acting bronchodilators in COPD and the risk of adverse cardiovascular events
The cardiovascular risk of concurrently using long-acting β2-agonists (LABAs) and anticholinergics (LAMAs) in COPD is uncertain. We assessed the comparative cardiovascular and cerebrovascular safety of adding a second long-acting bronchodilator in patients with COPD.
We identified a cohort of COPD patients, new users of LABA or the LAMA tiotropium during 2002–2012, from the UK Clinical Practice Research Datalink. Using high-dimensional propensity scores, each patient adding a second bronchodilator was matched with a patient who remained on monotherapy. Patients were followed for 1 year for the occurrence of...
Source: European Respiratory Journal - May 23, 2017 Category: Respiratory Medicine Authors: Suissa, S., Dell'Aniello, S., Ernst, P. Tags: COPD and smoking Original Articles: COPD Source Type: research
Impact of sleep disordered breathing on short-term post-operative outcome after elective coronary artery bypass graft surgery: a prospective observational study
Sleep disordered breathing (SDB) is common in patients with coronary disease, but its impact on post-operative recovery after coronary artery bypass graft surgery (CABG) is unclear. We therefore determined the effects of SDB on post-operative outcome after elective CABG.
In this prospective two-centre study, 219 patients due to receive elective CABG underwent cardiorespiratory polygraphy for SDB prior to surgery and were monitored for post-operative complications. The primary end-point was a composite of 30-day mortality or major post-operative complications (cardiac, respiratory, surgical, infectious, acute renal failure ...
Source: European Respiratory Journal - April 5, 2017 Category: Respiratory Medicine Authors: Rupprecht, S., Schultze, T., Nachtmann, A., Rastan, A. J., Doenst, T., Schwab, M., Witte, O. W., Rohe, S., Zwacka, I., Hoyer, H. Tags: Original Articles: Sleep Source Type: research
LATE-BREAKING ABSTRACT: The Sleep Apnea cardioVascular Endpoints (SAVE) study results - A trial of CPAP versus usual care in 2717 high cardiovascular risk patients with moderate-severe obstructive sleep apnea (OSA)
Conclusions: SAVE provides the first definitive randomised controlled trial evidence on the effectiveness of CPAP therapy on future CV events in patients with CV disease and co-occurring OSA.
Source: European Respiratory Journal - November 7, 2016 Category: Respiratory Medicine Authors: McEvoy, R. D., Antic, N., Heeley, E., Luo, Y., Mediano, O., McArdle, N., Tripathi, M., Lorenzi-Filho, G., Zhong, N., Anderson, C. S. Tags: 4.2 Sleep and Control of Breathing Source Type: research
New evaluation of gait symmetry/asymmetry in COPD patients using an accelerometer
Conclusion: LI measured by a tri-axial accelerometer evaluated gait symmetry/asymmetry accurately and might be clinically useful for the evaluation of balance in elderly COPD patients.
Source: European Respiratory Journal - November 7, 2016 Category: Respiratory Medicine Authors: Terui, Y., Iwakura, M., Sudo, E., Kawagoshi, A., Ookura, K., Satou, M., Hasegawa, K., Satake, M., Shioya, T. Tags: 9.2 Physiotherapists Source Type: research
Ventilatory pattern in chronic stroke survivors
The aim of this cross-sectional study was to compare dynamic lung volumes in chronic stroke survivors (SS) with a control group (CG) of healthy people matched by age and sex.Forced spirometries were performed, in line with the international statements. The reference values were calculated with the predictive equations proposed by Roca et al,1986.T test was used to determine differences in dynamic lung volumes between SS and CG.A cluster analysis was practiced to classify 2 different groups within the SS regarding to their dynamic lung volumes.The average age in SS (n=33) was 56.9±15.7 years. There were no significan...
Source: European Respiratory Journal - November 7, 2016 Category: Respiratory Medicine Authors: Lista Paz, A., Gonzalez Doniz, M. L., Sebio Garcia, R., Ortigueira Garcia, S. Tags: 9.2 Physiotherapists Source Type: research
Reliability of three respiratory muscle tests in post-stroke patients. A pilot study
Conclusion: The pilot data show a good inter-rater reliability of all 3 measures, but SNIP may require a practice session in stroke patients.
Source: European Respiratory Journal - November 7, 2016 Category: Respiratory Medicine Authors: Lewko, A., Sidaway, M., Krawczyk, M. Tags: 9.2 Physiotherapists Source Type: research
Echocardiography for defining the right ventricular contractile reserve in healthy subjects
Conclusions: These results provide age- and sex-related limits of normal RV contractile reserve as assessed by stress echocardiographic PASP, TAPSE, S and TAPSE/PASP. Right ventricular contractile reserve, however measured, correlates with exercise capacity.
Source: European Respiratory Journal - November 7, 2016 Category: Respiratory Medicine Authors: D'Alto, M., Pavelescu, A., Romeo, E., Argiento, P., Di Marco, G. M., Correra, A., Mattera Iacono, A., Russo, M. G., Naeije, R. Tags: 4.3 Pulmonary Circulation and Pulmonary Vascular Diseases Source Type: research
Prevalence of common diseases in COPD patients versus lung-healthy control subjects: Results from the German COSYCONET study
COSYCONET investigates the interrelationship of COPD and comorbidities with regard to course and prognosis of the disease. The present analysis examined the prevalence of selected common diseases in the COPD cohort compared to apparently lung-healthy subjects from the population-based reference cohorts KORA and SHIP.Spirometry was performed in all subjects and COPD patients were graded according to GOLD criteria. Subjects from KORA/SHIP without known COPD, asthma or chronic bronchitis and with FEV1/FVC≥0.7 were regarded as apparently lung-healthy. Prevalences of myocardial infarction, stroke, diabetes, hypertension, obe...
Source: European Respiratory Journal - November 7, 2016 Category: Respiratory Medicine Authors: Karrasch, S., Obst, A., Söhler, S., Thorand, B., Huth, C., Ladwig, K.-H., Flexeder, C., Wacker, M., Peters, A., Heinrich, J., Ewert, R., Nowak, D., Jörres, R. A., Vogelmeier, C., Gläser, S., Schulz, H., COSYCONET Study Group Tags: 6.1 Epidemiology Source Type: research
Cardio-metabolic disorder in grandparents associated with asthma in offspring: Results from a European 3-generation analysis
Conclusion: These preliminary results are similar to those observed previously in Northern-Europe. Grand-father CMD was associated with subsequent asthma in offspring independently of a family history of asthma. This may have important implications with regard to public health intervention.
Source: European Respiratory Journal - November 7, 2016 Category: Respiratory Medicine Authors: Carsin, A.-E., Real, F., Basagana, X., Accordini, S., Dharmage, S., Schlünssen, V., Benediktsdottir, B., Leynaert, B., Janson, C., Sunyer, J., Dratva, J., Jarvis, D., Svanes, C. Tags: 6.4 Genes and Environment Source Type: research
Ventricular-arterial coupling is preserved during exercise in patients with COPD
COPD is associated with a higher risk of cardiac and vascular disease and an increased risk of cardiovascular (CV) mortality. However, it is unknown whether intrinsic changes to the heart, vasculature or the interaction between these two systems are altered in patients with COPD, especially when the CV system is placed under stress. As such, the aim of this study was to investigate whether ventricular-arterial coupling (arterial elastance [Ea]/end-systolic elastance [Ees]) is altered in COPD patients during exercise. Fifteen COPD patients and 14 healthy age, sex and activity matched controls underwent incremental exercise ...
Source: European Respiratory Journal - November 7, 2016 Category: Respiratory Medicine Authors: Eves, N., Gelinas, J. Tags: 4.1 Clinical Physiology, Exercise and Functional Imaging Source Type: research
Concurrent use of long-acting bronchodilators in COPD and the risk of adverse cardiovascular events: A population-based study
In conclusion, the addition of a second long-acting bronchodilator in the real world setting treatment of COPD does not increase the risk of most cardiovascular events. The modest increase for heart failure may be due to residual confounding by indication and needs further investigation.
Source: European Respiratory Journal - November 7, 2016 Category: Respiratory Medicine Authors: Suissa, S., Dell'Aniello, S., Ernst, P. Tags: 5.1 Airway Pharmacology and Treatment Source Type: research
