The effect of 6-mercaptopurine treatment on experimentally induced pulmonary arterial hypertension
Conclusion: 6-MP partly reversed RV systolic pressure and RV afterload in established PAH. Together with the observed improved RV remodeling and cardiac function, 6-MP may be a promising intervention for PAH.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Sun, X.-Q., Kurakula, K., Happe, C., da Silva Goncalves Bos, D., Schalij, I., Vonk-Noordegraaf, A., de Man, F. S., Bogaard, H.-J., Goumans, M.-J. Tags: Pulmonary Circulation and Pulmonary Vascular Disease Source Type: research
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