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Source: International Journal of Cardiology
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Total 880 results found since Jan 2013.
Age-and-sex stratified prevalence of atrial fibrillation in rural Western India: Results of SMART-India, a population-based screening study
Early detection of Atrial Fibrillation (AF) is a public health priority across the globe because AF-related strokes are preventable. Despite an ongoing stroke epidemic in India, a public health strategy for AF screening and treatment is missing because the epidemiology of AF in India remains poorly defined.
Source: International Journal of Cardiology - December 5, 2018 Category: Cardiology Authors: Apurv Soni, Sunil Karna, Nisha Fahey, Saket Sanghai, Harshil Patil, Shyamsundar Raithatha, Sunil Thanvi, Somashekhar Nimbalkar, Ben Freedman, Jeroan Allison, David D. McManus Source Type: research
Impact of dronedarone on the risk of myocardial infarction and stroke in atrial fibrillation patients followed in general practices in Germany
The goal of this study was to analyze the impact of dronedarone on the risk of myocardial infarction and stroke in atrial fibrillation (AF) patients followed in general practices in Germany.
Source: International Journal of Cardiology - December 1, 2018 Category: Cardiology Authors: Joachim R. Ehrlich, Christiane Look, Karel Kostev, Carsten W. Israel, Andreas Goette Source Type: research
Antithrombotic therapy after acute coronary syndromes in patients with atrial fibrillation: Shouldn't we pay more attention to the risk of ischemic and thromboembolic events?
The management of antithrombotic therapy in patients with atrial fibrillation (AF) presenting an acute coronary syndrome (ACS) or undergoing percutaneous coronary intervention (PCI) is particularly complex. Oral anticoagulation (OAC) is superior to single or dual antiplatelet therapy (DAPT) for the prevention of thromboembolic complications (stroke and systemic embolism) due to AF, whereas DAPT with low-dose aspirin and a P2Y12 inhibitor is the recommended antithrombotic treatment to prevent ischemic events (myocardial infarction and stent thrombosis) in patients with ACS or undergoing PCI.
Source: International Journal of Cardiology - November 29, 2018 Category: Cardiology Authors: Jos é Luis Ferreiro, Joan Antoni Gómez-Hospital Tags: Editorial Source Type: research
Persistent atrial fibrillation: A systematic review and meta-analysis of invasive strategies
Persistent atrial fibrillation (AF) is associated with higher stroke and mortality risk than paroxysmal AF (pAF). Outcomes of catheter or surgical ablation are worse in patients with persistent AF than in pAF, and the optimal invasive rhythm control strategy has not been established.
Source: International Journal of Cardiology - November 29, 2018 Category: Cardiology Authors: Wouter R. Berger, Eva R. Meulendijks, Jacqueline Limpens, Nicoline W.E. van den Berg, Jolien Neefs, Antoine H.G. Driessen, S ébastien P.J. Krul, Wim Jan P. van Boven, Joris R. de Groot Source Type: research
Morphological determinators of platelet activation status in patients with atrial fibrillation
Stage of platelet activation is an important modulator of stroke risk associated with atrial fibrillation (AF). However, factors determining such activation status of thrombocytes in patients with AF are still not well studied.
Source: International Journal of Cardiology - November 17, 2018 Category: Cardiology Authors: Jedrzej Kosiuk, Tobias Uhe, Clara Stegmann, Laura Ueberham, Livio Bertagnolli, Nikolaos Dagres, Borislav Dinov, Andreas M üssigbrodt, Sergio Richter, Ingo Paetsch, Cosima Jahnke, Sebastian Hilbert, Philipp Sommer, Gerhard Hindricks, Andreas Bollmann Source Type: research
Sirtuin 5 promotes ischemia/reperfusion-induced blood-brain barrier damage after stroke
Circulating inflammatory cells influence endothelial function, which is important for vascular homeostasis and diseases [1]. Endothelial dysfunction is induced by several cardiovascular risk factors (e.g. hypertension, diabetes, and dyslipidemia) and environmental factors (e.g. hypoxia, infection, smoking, and air pollution) [2]. Recently, we have demonstrated that endothelial AMP-activated protein kinase (AMPK) plays an important role in the regulation of microvascular tone and blood pressure in mice [3].
Source: International Journal of Cardiology - November 10, 2018 Category: Cardiology Authors: Kimio Satoh, Hiroaki Shimokawa Tags: Editorial Source Type: research
Incidence and predictors of stroke in patients discharged with the diagnosis of acute coronary syndrome
Stroke is one the most feared cardiovascular disease due to its high risk of disability and its incidence after an acute coronary syndrome (ACS) is not uncommon.
Source: International Journal of Cardiology - November 1, 2018 Category: Cardiology Authors: Alberto Cordero, Mois és Rodríguez-Manero, Jose M. García-Acuña, Vicente Bertomeu-González, Rosa Agra-Bermejo, Belen Cid, Belen Alvarez, Vicente Bertomeu-Martínez, Jose R. González-Juanatey Source Type: research
A national study of the prevalence and risk factors associated with peripheral arterial disease from China: The China Hypertension Survey, 2012 –2015
Peripheral arterial disease (PAD) is the third leading cause of atherosclerotic vascular morbidity after coronary heart disease and stroke. Epidemiology data of PAD is very limited in low-income and middle-income countries. A national wide survey was conducted from October 2012 to December 2015 to assess the prevalence of PAD in China.
Source: International Journal of Cardiology - October 25, 2018 Category: Cardiology Authors: Zengwu Wang, Xin Wang, Guang Hao, Zuo Chen, Linfeng Zhang, Lan Shao, Ye Tian, Ying Dong, Congyi Zheng, Yuting Kang, Runlin Gao, China hypertension survey investigators Source Type: research
Impact of hospitalization in patients with atrial fibrillation: Implications for health-care providers and clinical management
For several years, stroke, thromboembolic events and oral anticoagulant (OAC) related major bleeding have been the most feared clinical events considered among atrial fibrillation (AF) [1]. Consequently, the most part of attention was drawn to optimization of OAC therapy to obtain a reduction of thromboembolic events keeping low the incidence of bleeding adverse events [1]. More recently, a lot of focus has been paid to other outcomes as hospitalization/rehospitalization [2], myocardial infarction [3] and death (both cardiovascular and all-cause death) [4].
Source: International Journal of Cardiology - October 23, 2018 Category: Cardiology Authors: Marco Proietti Tags: Editorial Source Type: research
Clinical profile and outcome of cardiac involvement in MELAS syndrome
We describe the clinical profile, outcome and clinical implication of MELAS-associated cardiomyopathy at a tertiary referral centre.
Source: International Journal of Cardiology - October 23, 2018 Category: Cardiology Authors: Alice Brambilla, Silvia Favilli, Iacopo Olivotto, Giovanni Battista Calabri, Giulio Porcedda, Luciano De Simone, Elena Procopio, Elisabetta Pasquini, Maria Alice Donati Source Type: research
Pulse rate variability predicts atrial fibrillation and cerebrovascular events in a large, population-based cohort
Many patients with atrial fibrillation (AF) present with stroke as their first clinical manifestation and since improved AF screening methods are thus required, we investigated whether pulse rate variability parameters predict future AF and cerebrovascular events.
Source: International Journal of Cardiology - October 9, 2018 Category: Cardiology Authors: John D. Sluyter, Carlos A. Camargo, Andrew Lowe, Robert K.R. Scragg Source Type: research
Finding the right balance
Patients with an indication for oral anticoagulation (OAC) that receive antiplatelet therapy after percutaneous coronary intervention (PCI) are challenging for the treating physician. It is of importance to balance their antithrombotic treatment to protect them from ischemic events, such as stent thrombosis as well as ischemic stroke without exposing them to an excess in bleeding. The current guidelines recommend a so-called triple therapy consisting of aspirin, clopidogrel and OAC for 1 –6 months after PCI depending on the patient's ischemic risk [1].
Source: International Journal of Cardiology - September 27, 2018 Category: Cardiology Authors: Alexander Goedel, Nikolaus Sarafoff Tags: Editorial Source Type: research
Primordial prevention of cardiovascular disease: Several challenges remain
The concept of primordial prevention, preventing the development of cardiovascular risk factors, has been re-emphasized by the American Heart Association (AHA) which has developed a simplified 7-item tool (body mass index, smoking status, diet, physical activity, blood pressure, blood cholesterol and glycaemia) to help promote cardiovascular health (CVH) in the population [1] (Table 1). The AHA's goal was to increase overall CVH in the US population by 20% by 2020 while reducing death from cardiovascular disease (CVD) and stroke by 20%.
Source: International Journal of Cardiology - September 21, 2018 Category: Cardiology Authors: Bamba Gaye, Donald M. Lloyd-Jones Tags: Editorial Source Type: research
Stroke prevention in atrial fibrillation: State of the art
Stroke prevention is the cornerstone of the management of patients with atrial fibrillation (AF). Individual stroke risk stratification is generally the first step of deciding whether oral anticoagulation (OAC) will benefit patients with AF. Given that existing approaches to the prediction of ‘high risk’ subjects are of limited value, the initial focus should be the identification of ‘low-risk’ patients who do not need antithrombotic therapy. For this, the CHA2DS2-VASc score (congestive heart failure, hypertension, age ≥ 75 [2 points], diabetes mellitus, previous stroke/tra nsient ischemic attack [2 points], ...
Source: International Journal of Cardiology - September 19, 2018 Category: Cardiology Authors: Yan-Guang Li, Gregory Y.H. Lip Tags: Review Source Type: research
New-onset atrial fibrillation in ICU: A FROG in the throat
We read with interest the recent paper by M. Arrigo et al. [1]. The authors provide for the first time prospective multicentre results on long-term prognosis of new-onset atrial fibrillation (NOAF) in critical illness patients, thus highlighting the need for a better understanding of the pathophysiological mechanisms involved. Indeed, although a major focus on stroke risk has been brought forward recently, heart failure events are one of the major determinants of the poor prognosis carried by AF patients in the general population as well as in post-ICU one's.
Source: International Journal of Cardiology - September 13, 2018 Category: Cardiology Authors: Charles Guenancia, Auguste Dargent, Audrey Large, Pascal Andreu, Jean-Pierre Quenot Tags: Letter to the Editor Source Type: research
