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Source: International Journal of Cardiology
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Total 880 results found since Jan 2013.
Volumetric and functional left atrial abnormalities in different disorders – are these alterations specific?
I am reading the paper of Keulards et al. in which the relationship between coronary microvascular resistance and left atrial (LA) strains as assessed by two-dimensional speckle-tracking echocardiography (2DSTE) was investigated [1]. Although the manuscript is well written and the discussion is clear, it needs some revision. Three-dimensional (3D) speckle-tracking echocardiography (3DSTE) is a more advanced non-invasive imaging method than 2DSTE. During 3DSTE, the same virtually created 3D model of the LA can be used for simultaneous assessment not only of LA strains but LA volumes and volume-based functional properties in...
Source: International Journal of Cardiology - September 3, 2021 Category: Cardiology Authors: Attila Nemes Tags: Letter to the Editor Source Type: research
In vitro fertilization exacerbates stroke size and neurological disability in wildtype mice
Assisted reproductive technologies (ART) induce premature vascular aging in human offspring. The related alterations are well-established risk factors for stroke and predictors of adverse stroke outcome. However, given the young age of the human ART population there is no information on the incidence and outcome of cerebrovascular complications in humans . In mice, ART alters the cardiovascular phenotype similarly to humans, thereby offering the possibility to study this problem.
Source: International Journal of Cardiology - August 22, 2021 Category: Cardiology Authors: N.R. Bonetti, T.A. Meister, R. Soria, A. Akhmedov, L. Liberale, S. Ministrini, A. Dogar, T.F. L üscher, F.H. Messerli, E. Rexhaj, G.G. Camici, J.H. Beer, U. Scherrer Source Type: research
Genetic factors may affect the severity of COVID-19
We have read with great interest of the article by Minhas et al. [1], in which indicates adjusted odds of myocardial injury, ischemic stroke and all-cause mortality are significantly higher in men compared to women with COVID-19.Higher inflammatory markers are present in men but associated similarly with risk in both men and women, suggesting that adverse cardiovascular outcomes in men vs. women are independent of cardiovascular comorbidities.
Source: International Journal of Cardiology - August 2, 2021 Category: Cardiology Authors: Zhenzhen Zheng, Yuanming Zhou, Xishi Sun, Zhiqiang Wang, Chaoyu Wang, Jiangpeng Lin, Ziyi Wang, Yanhong Liu, Xiaojuan Chen, Nanhong Li, Yu Zeng, Riken Chen Tags: Letter to the Editor Source Type: research
Association between acute myocardial infarction and death in 386 patients with a thrombus straddling a patent foramen ovale
Right atrial thrombi are rarely found straddling a patent foramen ovale (PFO). A thrombus straddling a PFO (TSPFO), also known as impending paradoxical embolism, is a medical emergency associated with up to 11.5% risk of death within 24 h of being diagnosed. We hypothesized that acute myocardial infarction (MI) and ischemic stroke (IS) diagnosed upon the admission of patients with TSPFO are associated with increased risk of death. We also investigated if specific acute therapies are associated with reduced in-hospital mortality.
Source: International Journal of Cardiology - July 7, 2021 Category: Cardiology Authors: Palak Shah, Amado Jimenez-Ruiz, Andrew Gibson, Juan C. Vargas-Gonz ález, Maria Bres-Bullrich, Rodrigo Bagur, Luciano A. Sposato Source Type: research
Antithrombotic therapy in the elderly: The more we know, the more we can offer
Atrial fibrillation (AF) and coronary artery disease commonly co-exist in elderly patients [1]. While long-term oral anticoagulation therapy is needed to prevent stroke and systemic embolism, antiplatelet agents are recommended to reduce the risk of coronary thrombotic events in this patient population [2]. Elderly patients are prone to both an increased risk of bleeding and of thrombotic events [3,4]. Therefore, keeping a favorable balance between ischemic and hemorrhagic risks in this growing population represents a major challenge in clinical practice.
Source: International Journal of Cardiology - July 6, 2021 Category: Cardiology Authors: Pedro A. Lemos, Patricia O. Guimar ães, Marcelo Franken, Otavio Berwanger Tags: Editorial Source Type: research
Cardiac imaging in ischemic stroke or transient ischemic attack of undetermined cause: Systematic review & meta-analysis
Patients with ischemic stroke or transient ischemic attack (TIA) of undetermined cause often undergo cardiac imaging in search of a cardioembolic source. As the choice of the most appropriate imaging approach is controversial and therapeutic implications have changed over time, we aimed to identify in patients with “cryptogenic stroke or TIA” the yield of transthoracic or transesophageal echocardiography (TTE or TEE) and cardiac computed tomography (CT).
Source: International Journal of Cardiology - June 28, 2021 Category: Cardiology Authors: Gerlinde van der Maten, Saskia Dijkstra, Matthijs F.L. Meijs, Clemens von Birgelen, Job van der Palen, Heleen M. den Hertog Source Type: research
The role of sex and inflammation in cardiovascular outcomes and mortality in COVID-19
Higher mortality in COVID-19 in men compared to women is recognized, but sex differences in cardiovascular events are less well established. We aimed to determine the independent contribution of sex to stroke, myocardial infarction and death in the setting of COVID-19 infection.
Source: International Journal of Cardiology - May 8, 2021 Category: Cardiology Authors: Anum Minhas, Julie K. Shade, Sung-Min Cho, Erin D. Michos, Thomas Metkus, Nisha A. Gilotra, Garima Sharma, Natalia Trayanova, Allison G. Hays Tags: Short communication Source Type: research
Aortic valve replacement vs. balloon-expandable and self-expandable transcatheter implantation: A network meta-analysis
Recently, observational data have raised concerns about safety of selfexpandable (SE) compared to balloon-expandable (BE) valves in TAVI, although potentially limited by patient selection bias. Methods. All Randomized Controlled Trials (RCTs) comparing BE vs. SE TAVI or/and vs. aortic valve replacement (AVR) were included and compared through Network Meta Analysis (NMA). All-cause and cardiovascular (CV) mortality were the primary endpoints, stroke, rates of permanent pacemaker implantation (PPI), moderate/severe paravalvular leak (PVL) and reintervention were the secondary endpoints.
Source: International Journal of Cardiology - May 8, 2021 Category: Cardiology Authors: Fabrizio D'Ascenzo, Francesco Bruno, Luca Baldetti, Ovidio De Filippo, Giorgio Marengo, Susanna Breviario, Francesco Melillo, Hans Gustav H ørsted Thyregod, Holger Thiele, Lars Sondergaard, Jeffrey J. Popma, Susheel Kodali, Luca Franchin, Margherita Anna Source Type: research
Frequency of cardiac arrhythmias in older adults: Findings from the Subclinical Atrial Fibrillation and Risk of Ischemic Stroke (SAFARIS) study
Prolonged monitoring of cardiac rhythm has been used to screen for subclinical atrial fibrillation (AF); little is known about other arrhythmias in the general population, especially in the elderly, who are at higher risk of arrhythmias.
Source: International Journal of Cardiology - May 6, 2021 Category: Cardiology Authors: Carlo Mannina, Zhezhen Jin, Kenji Matsumoto, Kazato Ito, Angelo Biviano, Mitchell S.V. Elkind, Tatjana Rundek, Shunichi Homma, Ralph L. Sacco, Marco R. Di Tullio Source Type: research
Detection of atrial fibrillation in asymptomatic at-risk individuals
The objective of this study is to determine the AF burden in an asymptomatic, at-risk population. We also sought to investigate potential predictors of undiagnosed AF.
Source: International Journal of Cardiology - April 28, 2021 Category: Cardiology Authors: Anatoly Langer, Jeff S. Healey, F. Russell Quinn, George Honos, Isabelle Nault, Mary Tan, Diane Camara, David M. Newman, Richard Godin, On Behalf of the AWARE AF Program Tags: Short communication Source Type: research
Apparent treatment resistant hypertension and the risk of recurrent cardiovascular events and mortality in patients with established vascular disease
To quantify the relation between apparent treatment resistant hypertension (aTRH) and the risk of recurrent major adverse cardiovascular events (MACE including stroke, myocardial infarction and vascular death) and mortality in patients with stable vascular disease.
Source: International Journal of Cardiology - April 28, 2021 Category: Cardiology Authors: Eline H. Groenland, Michiel L. Bots, Folkert W. Asselbergs, Gert J. de Borst, L. Jaap Kappelle, Frank L.J. Visseren, Wilko Spiering, on behalf of the UCC-SMART Study Group Source Type: research
Diastolic dysfunction in women with ischemia and non-obstructive coronary arteries (INOCA) – Could non-invasive imaging reveal the missing piece of puzzle?
A large proportion of patients with chronic coronary syndromes will not have obstructive coronary artery disease (CAD) on invasive coronary angiography, more often women than men [1]. Ischemia with non-obstructive coronary arteries (INOCA), once considered a benign condition, is now recognized to be associated with increased risk of adverse events, including heart failure (HF), myocardial infarction, stroke and cardiovascular death as well as increased number of hospitalizations [2 –5]. Among INOCA patients, those with evidence of both coronary microvascular and diastolic dysfunction seem to bear the highest risk of adve...
Source: International Journal of Cardiology - April 16, 2021 Category: Cardiology Authors: Anca Florian Tags: Editorial Source Type: research
Measuring apixaban levels in the elderly patient with non-valvular atrial fibrillation
Atrial fibrillation (AF) is the most common arrhythmia and its prevalence increases with age. As a result, elderly patients are at increased risk of AF-related stroke compared to younger patients [1]. It is estimated that AF accounts for 15% of all cases of ischemic stroke and 33% of stroke cases in the elderly [2].
Source: International Journal of Cardiology - April 8, 2021 Category: Cardiology Authors: Ran Nissan Tags: Editorial Source Type: research
Simplifying the approach to classical low-flow low-gradient severe aortic stenosis: A renewed emphasis on the resting transthoracic echocardiogram
Aortic stenosis (AS) represents the most commonly encountered valvular heart disease. Traditionally, severe AS is defined by an aortic valve area (AVA) less than or equal to 1.0 cm2 and mean aortic valve gradient (MG) greater than or equal to 40 mm Hg. In roughly 40% of encountered cases, however, Doppler echocardiography yields discordant findings—a calculated AVA suggestive of severe AS but a MG consistent with less-than-severe disease [1,2]. Assuming no error in measurement, these cases stem, in part, from low-flow states (defined as a resting stroke volume index, SVI, less than or equal to 35 mL/m2) and cons...
Source: International Journal of Cardiology - March 22, 2021 Category: Cardiology Authors: James W. Lloyd, Mackram F. Eleid Tags: Editorial Source Type: research
Oral anticoagulation and therapy of atrial flutter: discontinuation of anticoagulation revisited
Catheter ablation is a commonly performed procedure to achieve rhythm control in patients with typical atrial flutter (AFL) [1]. Although this procedure is considered curative, one-third of AFL patients have significant risk of developing atrial fibrillation (AF) [2] that along with coexistent AFL increases risk of developing serious symptoms [3]. Oral anticoagulation (OAC) is one of the three main pillars of the ABC pathway for integrated AF management [1]. Given the significant proportion of patients with AFL who are at risk to subsequently develop AF [2], stroke-prevention strategies are similarly recommended to patient...
Source: International Journal of Cardiology - March 17, 2021 Category: Cardiology Authors: Monika Gawa łko, Dobromir Dobrev Tags: Editorial Source Type: research
