Filtered By:
Source: International Journal of Cardiology
This page shows you your search results in order of date. This is page number 2.
Order by Relevance | Date
Total 880 results found since Jan 2013.
Atrial fibrillation burden and cognitive function; a new horizon in the digital health era?
Atrial fibrillation (AF) is the most prevalent clinical arrhythmia, is a major risk factor for stroke, and is associated with cardiovascular and total mortality. On the other hand, we have increasing evidence today on the association between AF and dementia which is another huge disease burden in the aging society. Numerous retrospective and prospective studies in recent years have reported a strong association between AF, cognitive decline, and dementia [1,2]. Such an association, however, need not be a causal relationship, because all these conditions very likely have a multifactorial interaction with other cardiovascula...
Source: International Journal of Cardiology - February 23, 2023 Category: Cardiology Authors: Ali Serdar Fak Tags: Editorial Source Type: research
Can carotid plaque assessment perform the role of a risk predictor for secondary prevention?
In clinical settings, secondary prevention of atherosclerotic cardiovascular disease (ASCVD) is suboptimal [1]; this is an important challenge for preventive cardiologists. For example, 20% of acute coronary syndrome survivors experience a subsequent cardiovascular event (stroke, myocardial infarction [MI], or cardiovascular death) within the first 365 days after the index MI. [2] A potential explanation for the higher incidence of ASCVD events in these patients derives from their heterogeneity in baseline risk; thus, reliable cardiovascular risk stratification strategies are required to identify extremely high-risk patients.
Source: International Journal of Cardiology - February 14, 2023 Category: Cardiology Authors: Kazuhiro Osawa Tags: Editorial Source Type: research
The role of adrenomedullin in acute coronary syndrome
In the study published by IJC [1] 7 circulating biomarkers related to hemostasis and fibrinolytic pathways, endothelial function and vascular regulation were analyzed in a cohort of 1370 patients with acute coronary syndrome. Moreover, their association with outcome of re-admission due to myocardial infarction, ischemic stroke, heart failure or death were assessed. Interestingly, their predictive value for outcome in relation to renal function was also determined. Chronic kidney disease patients have a well-known increased cardiovascular risk and have worse outcome after an acute coronary syndrome.
Source: International Journal of Cardiology - February 6, 2023 Category: Cardiology Authors: Roberto G. Carbone, Francesco Puppo Tags: Editorial Source Type: research
REACHing conclusions on the external applicability of the THEMIS into clinical practice
The THEMIS Study (Effect of Ticagrelor on Health Outcomes in Diabetes Mellitus Patients) was a phase 3 randomized, double-blinded, placebo-controlled trial from 2014 to 2016. Patients with angiographically proven coronary artery disease (CAD) and type 2 diabetes mellitus (T2DM), but no prior history of myocardial infarction (MI) or stroke, were randomized 1:1 to either ticagrelor or placebo in addition to low-dose aspirin for a median follow-up of 39.9 months. The randomized population (n = 19,220) had a median age of 66years, 31.4% were women, and there was a high prevalence of concomitant hypertension, dyslipidemi...
Source: International Journal of Cardiology - December 31, 2022 Category: Cardiology Authors: Rahul Gupta, Adriana C. Mares Tags: Editorial Source Type: research
The dilemma of thromboembolism prophylaxis in patient with acute heart failure
Despite advances in treatment, heart failure (HF) continues to be associated with high morbidity and mortality [1]. One of the reasons for this fact is the thrombogenicity seen in these patients through different mechanisms (Fig. 1) via Virchow's triad: blood stasis, endothelial dysfunction, and hypercoagulability; resulting in reported rates of up to 30% of venous thromboembolism (VTE), stroke, and sudden death among HF patients [2]. On the other hand, atrial fibrillation (AF) frequently coexists increasing the risk of thromboembolic events, and while the efficacy of anticoagulants in this last population has been proven ...
Source: International Journal of Cardiology - December 16, 2022 Category: Cardiology Authors: H. Amparo Taveras Tags: Editorial Source Type: research
Atrial fibrillation screening: Great debate on which approach to apply, which tools to use and which population to target
Atrial fibrillation (AF) is a common disease, particularly in the elderly and carries a substantial risk of stroke, which may be effectively prevented by the prescription of oral anticoagulants (OACs) in patients at risk [1]. This arrhythmia may appear in different forms (paroxysmal, persistent, permanent) and may be variably associated with an underlying cardiovascular disease (CVD). Regardless of this association, AF may be asymptomatic in a substantial proportion of cases, estimated to be around 30% [2].
Source: International Journal of Cardiology - December 11, 2022 Category: Cardiology Authors: Giuseppe Boriani, Jacopo Francesco Imberti, Marco Vitolo Tags: Editorial Source Type: research
Readmission in patients undergoing percutaneous patent foramen ovale closure in the United States
Current estimates suggest that a patent foramen ovale (PFO) may exist in up to 25% of the general population and is a potential risk factor for embolic, ischemic stroke. PFO closure complications include bleeding, need for procedure-related surgical intervention, pulmonary emboli, device malpositioning, new onset atrial arrhythmias, and transient atrioventricular block. Rates of PFO closure complications at a national level in the Unites States remain unknown. To address this, we performed a contemporary nationwide study using the 2016 and 2017 Nationwide Readmissions Database (NRD) to identify patterns of readmissions aft...
Source: International Journal of Cardiology - November 7, 2022 Category: Cardiology Authors: Chayakrit Krittanawong, Bing Yue, Muzamil Khawaja, Anirudh Kumar, Hafeez Ul Hassan Virk, Zhen Wang, Sana Hanif, Umair Khalid, Ali E. Denktas, Clifford J. Kavinsky, John J. Volpi, Hani Jneid Source Type: research
Screening for high-grade asymptomatic carotid artery stenosis in nonvalvular atrial fibrillation
The plea for screening for asymptomatic carotid artery stenosis [1] should be extended to patients with the association of asymptomatic carotid artery stenosis (CAS) and nonvalvular atrial fibrillation(NVAF). The rationale is that it is already recognised that high-grade CAS(stenosis of 50% or more) is prevalent in about 12% of NVAF patients aged>70 [2]. Furthermore, in a study where 103 consecutive ischemic stroke patients with NVAF and were screened for CAS, high-grade extracranial CAS was identified in 25 subjects.
Source: International Journal of Cardiology - November 4, 2022 Category: Cardiology Authors: Oscar M.P. Jolobe Tags: Letter to the Editor Source Type: research
Screening for atrial fibrillation to prevent stroke in elderly individuals with or without preexisting cardiovascular disease: A post hoc analysis of the randomized LOOP study
This study aimed to investigate whether established cardiovascular diseases (CVD) could help to identify the population more likely to benefit from AF screening.
Source: International Journal of Cardiology - October 31, 2022 Category: Cardiology Authors: Lucas Yixi Xing, S øren Zöga Diederichsen, Søren Højberg, Derk W. Krieger, Claus Graff, Morten S. Olesen, Axel Brandes, Lars Køber, Ketil Jørgen Haugan, Jesper Hastrup Svendsen Source Type: research
TAVI for patients with normal-flow low-gradient compared to high-gradient aortic stenosis
Normal-flow (stroke volume index, SVi>35 ml/m2) low-gradient (dPmean
Source: International Journal of Cardiology - October 24, 2022 Category: Cardiology Authors: Julius Steffen, David Andreae, Michael Nabauer, Nikolas Rei ßig, Philipp M. Doldi, Magda Haum, Martin Orban, Hans Theiss, Konstantinos Rizas, Daniel Braun, Sven Peterß, Jörg Hausleiter, Steffen Massberg, Simon Deseive Source Type: research
Atrial high-rate episode burden and stroke risks for patients with device-detected subclinical atrial fibrillation: A systematic review and meta-analysis
Atrial high-rate episode (AHRE) and stroke are related; however, the magnitude of the correlations between different AHRE burdens and stroke remains unknown. We analysed studies that evaluated this relationship.
Source: International Journal of Cardiology - October 12, 2022 Category: Cardiology Authors: Yanhai Meng, Yanbo Zhang, Changsheng Zhu, Changrong Nie, Ping Liu, Shuo Chang, Shuiyun Wang Tags: Review Source Type: research
Betablockers reduce oxygen pulse increase and performance in heart failure patients with preserved ejection fraction
Beta blockers (BB) reduce chronotropic response and exercise capacity in heart failure with preserved ejection fraction (HFpEF). To analyze the influence of BB on exercise performance and O 2 pulse increase as a surrogate for stroke volume in HFpEF.
Source: International Journal of Cardiology - October 8, 2022 Category: Cardiology Authors: Wernhart Simon, Papathanasiou Maria, Amir Abbas Mahabadi, Rassaf Tienush, Luedike Peter Source Type: research
Reply to: Among patients with MINOCA women versus men have the increased risks of MACE and stroke?
Du et al. re-analyzed the data from our meta-analysis using random effects model (REM) as opposed to fixed effects which mitigated the observed differences in MACE between men and women with MINOCA [1].
Source: International Journal of Cardiology - October 6, 2022 Category: Cardiology Authors: Rahul Chaudhary, Michael Bashline, Enrico M. Novelli, Kevin P. Bliden, Udaya S. Tantry, Oladipupo Olafiranye, Seyed Mehdi Nouraie, Paul A. Gurbel, John J. Pacella Tags: Letter to the Editor Source Type: research
Why do guidelines recommend screening for abdominal aortic aneurysms, but not for asymptomatic carotid stenosis? A Plea for a randomized controlled trial
Background:Current guidelines do not recommend screening for asymptomatic carotid artery stenosis (AsxCS). The rationale behind this recommendation is that detection of AsxCS may lead to an unnecessary carotid intervention. In contrast, screening for abdominal aortic aneurysms is strongly recommended.Methods: A critical analysis of the literature was performed to evaluate the implications of detecting AsxCS.Results: Patients with AsxCS are at high risk for future stroke, myocardial infarction and vascular death.
Source: International Journal of Cardiology - September 23, 2022 Category: Cardiology Authors: Kosmas I. Paraskevas, J. David Spence, Dimitri P. Mikhailidis, Pier Luigi Antignani, Peter Gloviczki, Hans-Henning Eckstein, Francesco Spinelli, Francesco Stilo, Luca Saba, Pavel Poredos, Alan Dardik, Christos D. Liapis, Armando Mansilha, Gianluca Faggiol Tags: Review Source Type: research
Among patients with MINOCA women versus men have the increased risks of MACE and stroke?
In a brief and wonderful meta-analysis [1] by Chaudhary and colleagues, the authors identified that among patients with myocardial infarction with nonobstructive coronary arteries (MINOCA) women versus men had increased risks of major adverse clinical events (MACE) (odds ratio [OR], 1.15; 95% confidence interval [CI], 1.04 –1.23; P = 0.004; I2 = 44.7%) and stroke (OR, 1.30; 95% CI, 1.01–1.68; P = 0.04; I2 = 0%); and similar risks of three other outcomes (all P > 0.05). However, these findings could be negatively influenced by the following two issues.
Source: International Journal of Cardiology - September 20, 2022 Category: Cardiology Authors: Lixin Du, Pan Wang, Hongwei Chen, Yu Zhang, Jianlan Ma, Ge Wen Tags: Letter to the Editor Source Type: research
