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Source: International Journal of Cardiology

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Total 880 results found since Jan 2013.

The shock index predicts acute mortality outcomes in stroke
Shock index (SI) (ratio between heart rate and systolic blood pressure) has been shown to be associated with poor mortality outcomes in trauma and pneumonia; however it has yet to be examined in stroke. We aimed to examine the relationship between SI and acute outcomes of inpatient, 3-day and 7-day mortality in stroke. Secondly, we aimed to compare SI and systolic blood pressure (SBP) alone in predicting above outcomes.
Source: International Journal of Cardiology - January 3, 2015 Category: Cardiology Authors: Stephen J. McCall, Stanley D. Musgrave, John F. Potter, Rachel Hale, Allan B. Clark, Mamas A. Mamas, Anthony K. Metcalf, Diana J. Day, Elizabeth A. Warburton, Max O. Bachmann, Phyo K. Myint, On behalf of the Anglia Stroke Clinical Network Evaluation Study Source Type: research

Reducing time delays in the management of ischemic stroke patients in Northern Italy
Thrombolysis represents the best therapy for ischemic stroke but the main limitation of its administration is time. The avoidable delay is a concept reflecting the effectiveness of management pathway. For this reason, we projected a study concerning the detection of main delays with following introduction of corrective factors. In this paper we describe the results after these corrections.
Source: International Journal of Cardiology - April 6, 2016 Category: Cardiology Authors: Simone Vidale, Marco Arnaboldi, Giacomo Bezzi, Giorgio Bono, Giampiero Grampa, Mario Guidotti, Patrizia Perrone, Andrea Salmaggi, Davide Zarcone, Alberto Zoli, Elio Agostoni, on behalf of Northern Lombardy Emergency Stroke Study Group Source Type: research

Trends in stroke incidence after hospitalization for atrial fibrillation in Sweden 1987 to 2006
Conclusion: We found a considerable decrease in risk of ischemic stroke in Sweden in patients without prior stroke and with a first hospital diagnosis of AF. There was an increased risk of hemorrhagic stroke, but because hemorrhagic stroke represented only a small proportion of all strokes, the overall risk of stroke declined.
Source: International Journal of Cardiology - April 5, 2012 Category: Cardiology Authors: Lars G. Olsson, Karl Swedberg, Georg Lappas, Simon Stewart, Annika Rosengren Tags: Original Articles Source Type: research

Comparative assessment of published atrial fibrillation stroke risk stratification schemes for predicting stroke, in a non-atrial fibrillation population: The Chin-Shan Community Cohort Study
Conclusion: Contemporary stroke risk stratification schema used for AF can also be applied to non-AF populations with a similar (modest) predictive value. Given their simplicity (e.g. CHADS2 score), these scores could potentially be used for a ‘quick’ evaluation of stroke risk in non-AF populations, in a similar manner to AF populations.
Source: International Journal of Cardiology - October 16, 2012 Category: Cardiology Authors: Gregory Y.H. Lip, Hung-Ju Lin, Kuo-Liong Chien, Hsiu-Ching Hsu, Ta-Chen Su, Ming-Fong Chen, Yuan-Teh Lee Tags: Original Articles Source Type: research

Stroke induced Sarcopenia: Muscle wasting and disability after stroke
Abstract: Stroke is the second leading cause of death and the leading cause of disability in Western countries. More than 60% of patients remain disabled, 50% of patients suffer from hemiparesis and 30% remain unable to walk without assistance. The skeletal muscle is the main effector organ accountable for disability in stroke. This disability is primarily attributed to the brain lesion; however less attention is paid to structural, metabolic and functional alterations of muscle tissue after stroke.Hemiparetic stroke leads to various muscle abnormalities: A combination of denervation, disuse, inflammation, remodelling and ...
Source: International Journal of Cardiology - November 13, 2013 Category: Cardiology Authors: Nadja Scherbakov, Stephan von Haehling, Stefan D. Anker, Ulrich Dirnagl, Wolfram Doehner Tags: Reviews Source Type: research

Relation of renal dysfunction to the increased risk of stroke and death in female patients with atrial fibrillation
Abstract: Background: Female patients with atrial fibrillation (AF) are at increased risk of stroke. It is unclear what contributes to the gender-related differences in stroke and mortality amongst AF patients. This is pertinent since oral anticoagulation use results in a significant reduction in stroke, as well as all-cause mortality.Objective: We investigated gender-related risk factors for stroke and mortality in a cohort of Chinese patients with AF.Methods: We studied 1034 AF patients (27% females, median age 75years) who were followed-up for an average of 1.9years for the principal primary endpoint of ‘ischaemic str...
Source: International Journal of Cardiology - February 1, 2013 Category: Cardiology Authors: Yutao Guo, Haijun Wang, Xiaoning Zhao, Yu Zhang, Dexian Zhang, Jingling Ma, Yutang Wang, Gregory Y.H. Lip Tags: Original Articles Source Type: research

The type of atrial fibrillation is associated with long‐term outcome in patients with acute ischemic stroke
Abstract: Background/objectives: We aimed to investigate the association between the type of atrial fibrillation (AF) and long-term outcome in terms of mortality and stroke recurrence in patients with ischemic stroke and non-valvular AF.Methods: All consecutive patients admitted with acute ischemic stroke to Alexandra Hospital between 1993 and 2010 were included in the analysis. Patients were categorized in 3 groups according to the type of AF (paroxysmal, persistent, and permanent) and were followed up for up to 10years after the index stroke or until death. The endpoints were inhospital, 30-day and 10-year stroke recurre...
Source: International Journal of Cardiology - May 18, 2012 Category: Cardiology Authors: G. Ntaios, A. Vemmou, E. Koroboki, P. Savvari, K. Makaritsis, M. Saliaris, G. Andrikopoulos, K. Vemmos Tags: Original Articles Source Type: research

Hyperuricemia and the risk of ischemic stroke in patients with atrial fibrillation — Could it refine clinical risk stratification in AF?
Conclusions: Hyperuricemia was a significant risk factor of stroke which could potentially refine the clinical risk stratification in AF. It deserves a prospective trial to investigate whether it would change the current strategy for stroke preventions using oral anticoagulants.
Source: International Journal of Cardiology - December 2, 2013 Category: Cardiology Authors: Tze-Fan Chao, Chia-Jen Liu, Su-Jung Chen, Kang-Ling Wang, Yenn-Jiang Lin, Shih-Lin Chang, Li-Wei Lo, Yu-Feng Hu, Ta-Chuan Tuan, Tzeng-Ji Chen, Hsuan-Ming Tsao, Shih-Ann Chen Tags: Original Articles Source Type: research

Renal dysfunction and long-term risk of ischemic and hemorrhagic stroke following coronary artery bypass grafting
Conclusions: Renal dysfunction is associated with increased long-term risk of stroke after primary isolated CABG. The impact of renal dysfunction on risk of stroke appears to be similar for both men and women.
Source: International Journal of Cardiology - December 6, 2012 Category: Cardiology Authors: Martin J. Holzmann, Erik Ahlbäck, Anders Jeppsson, Ulrik Sartipy Tags: Original Articles Source Type: research

Performance of Framingham cardiovascular disease (CVD) predictions in the Rotterdam Study taking into account competing risks and disentangling CVD into coronary heart disease (CHD) and stroke
Conclusions: Framingham CVD risk predictions perform well in the low- to intermediate risk categories in the Rotterdam Study. Disentangling CVD into CHD and stroke separately provides additional information about the individual contribution of CHD and stroke to total individual CVD risk.
Source: International Journal of Cardiology - January 17, 2014 Category: Cardiology Authors: Bob J.H. van Kempen, Bart S. Ferket, Maryam Kavousi, Maarten J.G. Leening, Ewout W. Steyerberg, M. Arfan Ikram, Jacqueline C.M. Witteman, Albert Hofman, Oscar H. Franco, M.G. Myriam Hunink Tags: Original Articles Source Type: research

Factors influencing pre-hospital delay among acute ischemic stroke patients in the midlands of China
The “time is brain” concept is used to signify that the treatment of stroke should be considered as an emergency . The effectiveness of treatment in the early stages of ischemic stroke directly determines the prognosis of stroke patients, and timely medical intervention can reduce the risk of death or disability. Therefore, reducing the delay in seeking timely treatment is essential to the successful treatment of patients during the early stages of stroke. However, few cases are treated with alteplase (rt-PA), which is the first-line emergency therapy for acute ischemic stroke, due to significant pre-hospital delays . ...
Source: International Journal of Cardiology - February 3, 2014 Category: Cardiology Authors: Huajie Yang, Juan Zhang, Jun Xie, Chen Yang, Xiaoxin Dong, Yanhong Gong, Shiyi Cao, Xiaoxv Yin, Zhihong Wang, Zuxun Lu Tags: Letters to the Editor Source Type: research

Clampless off-pump surgery reduces stroke in patients with left main disease
Conclusions: This study shows the superiority of OPCAB for patients with LMD with regards to risk-adjusted outcomes other than mortality. A “clampless OPCAB strategy”, effectively reduces stroke yielding similar early outcomes as PCI.
Source: International Journal of Cardiology - June 25, 2012 Category: Cardiology Authors: Maximilian Y. Emmert, Sacha P. Salzberg, Burkhardt Seifert, Jacques Scherman, Andre Plass, Christoph T. Starck, Oliver Theusinger, Simon P. Hoerstrup, Jürg Grünenfelder, Stephan Jacobs, Volkmar Falk Tags: Original Articles Source Type: research

Stroke risk and suboptimal thromboprophylaxis in Chinese patients with atrial fibrillation: Would the novel oral anticoagulants have an impact?
Abstract: Background: The risk of stroke associated with atrial fibrillation (AF) is higher in Far Eastern population than in Western population, and warfarin use suboptimal. There is uncertainty whether the novel oral anticoagulants (NOACs) would have a major impact on stroke prevention in Far Eastern populations with AF.Objectives: We investigated current antithrombotic therapy use on stroke and bleeding risk, determinants of warfarin use and performed a modeling analysis of the net clinical benefit of the NOACs (apixaban, dabigatran) in a large cohort of Chinese patients with AF.Methods: We studied 1034 Chinese patients...
Source: International Journal of Cardiology - October 24, 2012 Category: Cardiology Authors: Yutao Guo, Ron Pisters, Stavros Apostolakis, Andrew D. Blann, Haijun Wang, Xiaoning Zhao, Yu Zhang, Dexian Zhang, Jingling Ma, Yutang Wang, Gregory Y.H. Lip Tags: Original Articles Source Type: research