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Source: International Journal of Cardiology

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Total 880 results found since Jan 2013.

Percutaneous left atrial appendage closure with complex anatomy by using the staged ‘kissing-Watchman’ technology with double devices
Left atrial appendage closure (LAAC) is an efficient alternative of oral anticoagulation to prevent stroke in patients with non-valvular atrial fibrillation (NVAF). Due to complexities of LAA anatomy, a complete closure may not always be obtained with a single device. The aim of this study was to evaluate the feasibility and safety of the staged ‘kissing-Watchman’ technology to occlude the LAA with complex anatomy.
Source: International Journal of Cardiology - May 4, 2018 Category: Cardiology Authors: Lisheng Jiang, Erich Duenninger, Manuela Muenzel, Xin Xue, Adam Fazakas, Thorsten Keil, Jiangtao Yu Tags: Short communication Source Type: research

‘Some doors are better left closed’: Using LAA occluders as an alternative to warfarin in very high-risk dialysed patients with atrial fibrillation
Since 2011, when the EMA approved the treatment with novel oral anticoagulants (NOACs) for primary prevention of cardio-embolic stroke in patients with atrial fibrillation (AF), a reasonable question repeatedly arose: “Will NOACs become the new standard of care in anticoagulation therapy?” [1]. While for many cathegories of patients the answer soon become positive [2], the sub-group of advanced chronic kidney disease (CKD) 5D stage (in dialysis) has never received a “yes” from either FDA or EMA (none of t hem allowing the use of NOACs in 5D CKD).
Source: International Journal of Cardiology - April 27, 2018 Category: Cardiology Authors: Alexandru Burlacu, Adrian Covic Tags: Editorial Source Type: research

Disentangling the risk of atrial fibrillation detected after ischemic stroke (AFDAS): A real challenge in clinical practice
Atrial fibrillation (AF) can be newly-diagnosed in up to 24% of patients with ischemic stroke [1]. The entity so called “AF detected after stroke” (AFDAS) has been created to acknowledge the complexity of diagnosing and managing these patients [2]. AFDAS may be a pre-existing AF condition that is unknown and/or asymptomatic, and is only diagnosed because of thorough post-stroke electrocardiographic monitoring in a yet unknown proportion of patients. Conversely, it may also be the consequence of neurogenic AF mechanisms triggered by the presence of a stroke.
Source: International Journal of Cardiology - April 26, 2018 Category: Cardiology Authors: Luciano A. Sposato, Renato D. Lopes Tags: Editorial Source Type: research

Characteristics and outcomes of ischemic stroke in patients with known atrial fibrillation or atrial fibrillation diagnosed after stroke
It is unclear whether ischemic stroke patients with known atrial fibrillation (KAF) had different outcomes than those with atrial fibrillation diagnosed after stroke (AFDAS). We aimed to explore the characteristics and outcomes in ischemic stroke patients with KAF or AFDAS.
Source: International Journal of Cardiology - April 26, 2018 Category: Cardiology Authors: Cheng-Yang Hsieh, Cheng-Han Lee, Darren Philbert Wu, Sheng-Feng Sung Source Type: research

Different safety profiles of oral anticoagulants in very elderly non-valvular atrial fibrillation patients: A retrospective propensity score matched cohort study
Vitamin K antagonists (VKAs) have been shown to decrease the risk of ischemic stroke and systemic embolism in patients with non-valvular atrial fibrillation (NVAF). [1] The non-VKA oral anticoagulants (NOACs) are now increasingly used as an alternative to VKAs thanks to their convenient, fixed dose and no requirement for monitoring. NOACs have shown non-inferiority to warfarin for the prevention of stroke and systemic embolism, with marked reduction in the risk of intracerebral haemorrhage [2].
Source: International Journal of Cardiology - April 25, 2018 Category: Cardiology Authors: Giacomo Zoppellaro, Luca Zanella, Gentian Denas, Nicola Gennaro, Eliana Ferroni, Ugo Fedeli, Seena Padayattil Jose, Giorgio Costa, Maria Chiara Corti, Margherita Andretta, Vittorio Pengo Source Type: research

Increased risk of ischemic stroke associated with new-onset atrial fibrillation complicating acute coronary syndrome: A systematic review and meta-analysis
Atrial fibrillation has been established as a major risk factor of ischemic stroke, however, the influence of new-onset atrial fibrillation (NOAF) complicating acute coronary syndrome (ACS) on ischemic stroke remains controversial. This meta-analysis aimed to validate the association between NOAF complicating ACS and ischemic stroke.
Source: International Journal of Cardiology - April 23, 2018 Category: Cardiology Authors: Jiachen Luo, Hongqiang Li, Xiaoming Qin, Baoxin Liu, Jinlong Zhao, Guli Maihe, Zhiqiang Li, Yidong Wei Source Type: research

Disentangling the risk of atrial fibrillation detected after ischemic stroke (AFDAS): A real challenge in clinical practice
Atrial fibrillation (AF) can be newly-diagnosed in up to 24% of patients with ischemic stroke [1]. The entity so called “AF detected after stroke” (AFDAS) has been created to acknowledge the complexity of diagnosing and managing these patients [2]. AFDAS may be a pre-existing AF condition that is unknown and/or asymptomatic, and is only diagnosed because of thorough post-stroke electrocardiographic monitoring in a yet unknown proportion of patients. Conversely, it may also be the consequence of neurogenic AF mechanisms triggered by the presence of a stroke.
Source: International Journal of Cardiology - April 13, 2018 Category: Cardiology Authors: Luciano A. Sposato, Renato D. Lopes Tags: Editorial Source Type: research

Characteristics and outcomes of ischemic stroke in patients with known atrial fibrillation or atrial fibrillation diagnosed after stroke
It is unclear whether ischemic stroke patients with known atrial fibrillation (KAF) had different outcomes than those with atrial fibrillation diagnosed after stroke (AFDAS). We aimed to explore the characteristics and outcomes in ischemic stroke patients with KAF or AFDAS.
Source: International Journal of Cardiology - April 13, 2018 Category: Cardiology Authors: Cheng-Yang Hsieh, Cheng-Han Lee, Darren Philbert Wu, Sheng-Feng Sung Source Type: research

Right ventricular energetics and power in pulmonary regurgitation vs. stenosis using four  dimensional phase contrast magnetic resonance
We investigated a full energetic profile of pressure and volume loaded right ventricle (RV) in porcine models by evaluating kinetic energy (KE), stroke power, power output and power loss across pulmonary valves with stenosis (PS) or with regurgitation (PR).
Source: International Journal of Cardiology - April 4, 2018 Category: Cardiology Authors: Joao Filipe Fernandes, James M. Hammel, Jia Zhou, Yunbin Xiao, Manuela Chen, Rita Alves, John Lof, Stuart M. Grieve, Andreas Schuster, Titus Kuehne, Shelby Kutty Source Type: research

Right ventricular energetics and power in pulmonary regurgitation vs. stenosis using four ­dimensional phase­contrast magnetic resonance
We investigated a full energetic profile of pressure and volume loaded right ventricle (RV) in porcine models by evaluating kinetic energy (KE), stroke power, power output and power loss across pulmonary valves with stenosis (PS) or with regurgitation (PR).
Source: International Journal of Cardiology - April 4, 2018 Category: Cardiology Authors: Joao Filipe Fernandes, James M. Hammel, Jia Zhou, Yunbin Xiao, Manuela Chen, Rita Alves, John Lof, Stuart M. Grieve, Andreas Schuster, Titus Kuehne, Shelby Kutty Source Type: research

Looking beyond luminal stenosis in carotid artery disease
I read with interest the comments of Paraskevas and Naylor on the influence of asymptomatic carotid artery stenosis on peri-operative stroke following coronary artery bypass grafting (CABG). The authors have significant expertise in this field and I am in agreement with the views expressed which are in keeping with the findings of our study.
Source: International Journal of Cardiology - April 3, 2018 Category: Cardiology Authors: P. Narayan Tags: Letter to the Editor Source Type: research

Ultrasound cardiac calcification as a marker of subclinical atherosclerosis and future cardiovascular events in clinical practice: Is there enough evidence?
In the current IJC issue, Di Minno et al. [1] report an informative systematic review and meta-analysis of prior studies assessing cardiovascular morbidity and mortality in subjects categorized on the presence or absence of aortic valve sclerosis or calcification, using standard transthoracic echocardiography: they confirm that this simple and widely accessible marker is robustly associated with coronary artery disease (CAD), stroke and cardiovascular (CV) mortality, almost two decades after the report of this intriguing association by Catherine Otto [2].
Source: International Journal of Cardiology - April 3, 2018 Category: Cardiology Authors: Nicola Gaibazzi, Carmine Mazzone, Pompilio Faggiano Tags: Editorial Source Type: research

Sirtuin 5 as a novel target to blunt blood –brain barrier damage induced by cerebral ischemia/reperfusion injury
This study sought to determine whether SIRT5 contributes to BBB damage fo llowing I/R brain injury.
Source: International Journal of Cardiology - April 3, 2018 Category: Cardiology Authors: Candela Diaz-Ca ñestro, Mario Merlini, Nicole R. Bonetti, Luca Liberale, Patricia Wüst, Sylvie Briand-Schumacher, Jan Klohs, Sara Costantino, Melroy Miranda, Gabriele Schoedon-Geiser, Gerd A. Kullak-Ublick, Alexander Akhmedov, Francesco Paneni, Jürg H. Source Type: research