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Source: Journal of Neurology
Condition: Ischemic Stroke
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Total 227 results found since Jan 2013.
Brain MRI correlations with disease burden and biomarkers in Fabry disease
ConclusionBrain MRI revealed progressive lacunar infarctions, white matter hyperintensities, and decreased brain volume in patients with Fabry disease. Brain MRI lesions were closely related to onset-age; disease duration, severity, burden; and plasma Lyso-Gb3. However, they were not associated with sex, α-galactosidase A activity, orGLA mutation type.
Source: Journal of Neurology - September 20, 2023 Category: Neurology Source Type: research
A typology of cerebral small vessel disease based on imaging markers
ConclusionThe study confirmed the existence of different SVD types with different relationships to stroke outcome. EPVS and WMH were identified as imaging features of presumably early progression. The number of microbleeds and WMH severity appear to be promising biomarkers for distinguishing clinical subgroups. Further understanding of SVD progression might require consideration of refined SVD features, e.g., for EPVS and type of lacunes.
Source: Journal of Neurology - September 20, 2023 Category: Neurology Source Type: research
Strokecopilot: a literature-based clinical decision support system for acute ischemic stroke treatment
ConclusionStrokecopilot is a literature-based CDSS, developed to support neurologists in the management of the acute phase of AIS.
Source: Journal of Neurology - September 5, 2023 Category: Neurology Source Type: research
Frequency and predictors of poststroke epilepsy after mechanical thrombectomy for large vessel occlusion stroke: results from a multicenter cohort study
ConclusionIn our study, patients with large vessel occlusion stroke receiving MT had a 9% prevalence of PSE over a median follow-up period of 6.5 years. Besides larger infarct size, presence of cerebral microbleeds on brain MRI predicted PSE occurrence.
Source: Journal of Neurology - September 2, 2023 Category: Neurology Source Type: research
Intravenous thrombolysis and mechanical recanalization for acute ischemic stroke in deep brain stimulation patients: a case series
ConclusionIVT and MT were tolerated by four patients with ischemic stroke more than 6 months after DBS surgery without bleeding complications.
Source: Journal of Neurology - August 12, 2023 Category: Neurology Source Type: research
Identifying large vessel occlusion at first glance in telemedicine
ConclusionThese findings confirm that the presence of head and/or gaze deviation serves as a reliable biomarker in stroke-based telemedicine for the diagnosis of LVO, as well as a strong indicator for MT. Furthermore, this marker is just as reliable as the NIHSS score but easier to assess. We therefore suggest that any stroke patient who displays head and/or gaze deviation should immediately be scheduled for vessel imaging and subsequently transported to a MT-competent center.
Source: Journal of Neurology - August 12, 2023 Category: Neurology Source Type: research
Left ventricular hypertrophy and left atrial size are associated with ischemic strokes among non-vitamin K antagonist oral anticoagulant users
ConclusionsPrior cerebrovascular events, diabetes, left ventricular hypertrophy, and increased left atrial size are risk factors for developing an IS among NOAC users.
Source: Journal of Neurology - August 7, 2023 Category: Neurology Source Type: research
Safety and efficacy of intravenous thrombolysis in patients with acute ischemic stroke taking direct oral anticoagulants prior to stroke: a meta-analysis
ConclusionThe meta-analysis indicated that taking DOACs prior to stroke does not significantly increase the risk of sICH in selected patients with AIS treated with IVT. Furthermore, the benefits of IVT in selected patients taking DOACs appear to be comparable to those not taking anticoagulants. Further research is warranted to confirm the findings.
Source: Journal of Neurology - June 14, 2023 Category: Neurology Source Type: research
Pupillometry in the follow-up of patients undergoing EVT - prediction of space-occupying hemispheric infarction
ConclusionOur data suggest associations between noninvasively detected changes in pupillary reactivity and BE early after LVO-EVT. Pupillometry may identify patients who are unlikely to develop BE and may not need repetitive follow-up-imaging or rescue-therapy.
Source: Journal of Neurology - June 10, 2023 Category: Neurology Source Type: research
Prediction of underlying atrial fibrillation in patients with a cryptogenic stroke: results from the NOR-FIB Study
ConclusionClinical risk scores may guide a personalized evaluation approach in CS patients. Increasing awareness of the usage of available AF-predicting scores may optimize the arrhythmia detection pathway in stroke units.
Source: Journal of Neurology - May 10, 2023 Category: Neurology Source Type: research
Self-reported life-space mobility in the first year after ischemic stroke: longitudinal findings from the MOBITEC-Stroke project
ConclusionRoutinely assessing LSA starting value, pre-stroke mobility limitation, and FES-I may help clinicians identify patients at increased risk of failure to improve LSA.
Source: Journal of Neurology - May 4, 2023 Category: Neurology Source Type: research
Correction to: Factors associated with migraine aura-like symptoms in acute ischemic stroke
Source: Journal of Neurology - April 24, 2023 Category: Neurology Source Type: research
Data lake-driven analytics identify nocturnal non-dipping of heart rate as predictor of unfavorable stroke outcome at discharge
ConclusionsOur data suggest that a lack of circadian HR modulation, specifically nocturnal non-dipping, is associated with short-term unfavorable functional outcome after stroke, and that including HR into machine learning-based prediction models may lead to improved stroke outcome prediction.
Source: Journal of Neurology - April 20, 2023 Category: Neurology Source Type: research
Detection of patent foramen ovale in patients with ischemic stroke on prospective ECG-gated cardiac CT compared to transthoracic echocardiography
ConclusionProspective ECG-gated cardiac CT acquired during the acute stroke imaging protocol does not appear to be a suitable screening method for PFO due to its low sensitivity. Our data suggest that if cardiac CT is used as a first-line screening method for cardioembolism, additional echocardiography remains indicated in young patients with cryptogenic stroke, in whom PFO detection would have therapeutic consequences. These results need to be confirmed in larger cohorts.
Source: Journal of Neurology - April 7, 2023 Category: Neurology Source Type: research
