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Source: Journal of Neurology
Condition: Ischemic Stroke

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Total 227 results found since Jan 2013.

Myocardial infarction, stroke and cardiovascular mortality among migraine patients: a systematic review and meta-analysis
ConclusionMigraine, especially migraine with aura, is associated with myocardial infarction and stroke. Migraine with aura increases the risk of overall cardiovascular mortality.
Source: Journal of Neurology - January 8, 2022 Category: Neurology Source Type: research

Intraluminal carotid thrombosis and acute ischemic stroke associated with COVID-19
AbstractCOVID-19 (Coronavirus disease 2019) caused by SARS-CoV-2 has a diverse constellation of neurological manifestations that include encephalopathy, stroke, Guillain –Barré syndrome, myelitis, and encephalitis. Intraluminal carotid thrombi (ILT) are infrequent lesions seen in only 1.6% of patients with acute ischemic stroke. Underlying atherosclerosis is the most common lesion associated with ILT formation. However, with COVID-19, we have encountered ILT in p atients without significant atherosclerotic disease. The endothelial inflammation and hypercoagulable state associated with COVID-19 pose a risk of arterial an...
Source: Journal of Neurology - November 3, 2021 Category: Neurology Source Type: research

Safety and outcomes of endovascular treatment in patients with very severe acute ischemic stroke
ConclusionsIn patients with very severe neurological deficit, EVT was safe and successful recanalization was strongly associated with better functional outcome at 90  days.
Source: Journal of Neurology - October 7, 2021 Category: Neurology Source Type: research

Hospital admissions of acute cerebrovascular diseases during and after the first wave of the COVID-19 pandemic: a state-wide experience from Austria
AbstractWe investigated hospital admission rates for the entire spectrum of acute cerebrovascular diseases and of recanalization treatments for ischaemic stroke (IS) in the Austrian federal state of Styria during and also after the first coronavirus disease 2019 (COVID-19) wave. We retrospectively identified all patients with transient ischaemic attack (TIA), IS and non-traumatic intracranial haemorrhage (ICH; including intracerebral, subdural and subarachnoid bleeding types) admitted to one of the 11 public hospitals in Styria (covering  >  95% of inhospital cerebrovascular events in this region). Information was e...
Source: Journal of Neurology - September 27, 2021 Category: Neurology Source Type: research

Thrombectomy with or without thrombolysis in patients with acute ischemic stroke: a systematic review and meta-analysis
ConclusionsOutcomes were similar for d-MT and IVT  + MT, with d-MT having a lower risk of any ICH. We need to focus on precision medicine in the future.RegistrationURL:http://inplasy.com; Unique identifier: INPLASY202130094.
Source: Journal of Neurology - September 14, 2021 Category: Neurology Source Type: research

Early anticoagulation in atrial fibrillation-related acute ischaemic stroke: efficacy and safety profile
ConclusionsEarly anticoagulation was associated with lower ischaemic recurrence and better functional outcome at 3 months. Additional studies are needed to better clarify its haemorrhagic risk.
Source: Journal of Neurology - September 9, 2021 Category: Neurology Source Type: research

Detection of large vessel occlusion stroke with electroencephalography in the emergency room: first results of the ELECTRA-STROKE study
ConclusionDry electrode EEG is a promising tool for LVO-a stroke detection, but data quality needs to be improved and validation in the prehospital setting is necessary. (TRN: NCT03699397, registered October 9 2018).
Source: Journal of Neurology - September 2, 2021 Category: Neurology Source Type: research

Decrease in intravenous thrombolysis and poor short-term functional prognosis for acute ischemic stroke during the COVID-19 pandemic
ConclusionsThe COVID-19 pandemic caused the decrease of admissions and prolonged the time of the green channel for stroke, which led to the worse short-term prognosis of AIS patients during the pandemic. It ’s necessary to ensure an effective green channel and provide adequate medical resources during the pandemic period to reduce the damage caused by COVID-19.
Source: Journal of Neurology - August 11, 2021 Category: Neurology Source Type: research

Neurological manifestations of patients infected with the SARS-CoV-2: a systematic review of the literature
ConclusionThis updated review of literature, shows that headache, skeletal muscle injury, psychiatric disorders, impaired consciousness, and gustatory/olfactory dysfunction were the most common neurological symptoms of COVID-19 patients. Impaired consciousness and acute cerebrovascular events were significantly higher among patients with a severe infection. AIS patients required ICU admission in 63% of cases, while intra-hospital mortality rate was close to 23%.
Source: Journal of Neurology - July 19, 2021 Category: Neurology Source Type: research

Frequency of silent brain infarction in transient global amnesia
ConclusionsIn a relevant proportion of clinical TGA patients, MRI reveals acute ischemic cerebral lesions. Therefore, cerebral MRI should be performed in patients with TGA to identify a possible cardiac involvement and to detect stroke chameleons.
Source: Journal of Neurology - July 17, 2021 Category: Neurology Source Type: research

Risk of intracranial haemorrhage and ischaemic stroke after convexity subarachnoid haemorrhage in cerebral amyloid angiopathy: international individual patient data pooled analysis
ConclusionsPatients with cSAH associated with probable or possible CAA have high risk of future ICH and recurrent cSAH. Convexity SAH associated with probable (vs possible) CAA is associated with increased risk of ICH, and cSAH but not ischemic stroke. Our data provide precise risk estimates for key vascular events after cSAH associated with CAA which can inform management decisions.
Source: Journal of Neurology - July 17, 2021 Category: Neurology Source Type: research

Cystatin C predicts futile recanalization in patients with acute ischemic stroke after endovascular treatment
ConclusionsA higher level of cystatin C is associated with unfavourable outcomes at 3  months in anterior circulation acute ischaemic stroke patients with endovascular thrombectomy.
Source: Journal of Neurology - July 5, 2021 Category: Neurology Source Type: research

MRI radiomic features-based machine learning approach to classify ischemic stroke onset time
ConclusionsA unique deep learning model based on DWI/ADC radiomic features was constructed for TSS classification, which could aid in decision making for thrombolysis in patients with unknown stroke onset.
Source: Journal of Neurology - July 4, 2021 Category: Neurology Source Type: research

The Clock Drawing Test as a predictor of cognitive decline in non-demented stroke patients
ConclusionA bedside cognitive screening with the CDT helps identifying patients at higher risk of PSCI.
Source: Journal of Neurology - June 6, 2021 Category: Neurology Source Type: research

Impact of the COVID-19 lockdown on the adherence of stroke patients to direct oral anticoagulants: a secondary analysis from the MAAESTRO study
ConclusionOur data suggest that a major disruption of social life (i.e., the imposed COVID-19 lockdown) is unlikely to relevantly affect the medication intake behaviour of patients with high pre-established adherence, but might have an impact in patients with previously suboptimal adherence.Trial registration numberMAAESTRO: electronic Monitoring and improvement of Adherence to direct oral Anticoagulant treatment —a randomized crossover study of an Educational and reminder-based intervention in ischaemic STROke patients under polypharmacy, NCT03344146.
Source: Journal of Neurology - June 3, 2021 Category: Neurology Source Type: research