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Source: Journal of Neurology
Condition: Ischemic Stroke

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Total 227 results found since Jan 2013.

Atrial cardiomyopathy and incident ischemic stroke risk: a systematic review and meta-analysis
ConclusionAtrial cardiomyopathy markers, including electrocardiographic markers, serum markers, LA structural and functional markers, can be used to stratify the risk of incident ischemic stroke.
Source: Journal of Neurology - April 4, 2023 Category: Neurology Source Type: research

Factors associated with migraine aura-like symptoms in acute ischemic stroke
Source: Journal of Neurology - April 4, 2023 Category: Neurology Source Type: research

Exome-based gene panel analysis in a cohort of acute juvenile ischemic stroke patients:relevance of NOTCH3 and GLA variants
ConclusionGenetic screening for Fabry ’s disease in cardioembolic and lacunar stroke as well as CADASIL in lacunar stroke might be beneficial in routine medical work-up of acute juvenile ischemic stroke.
Source: Journal of Neurology - February 28, 2023 Category: Neurology Source Type: research

Patterns of acute ischemic stroke and intracranial hemorrhage in patients with COVID-19
In this study, we sought to investigate associations between neuroimaging findings with clinical, demographic, blood and cerebrospinal fluid (CSF) parameters, pre-existing conditions and the severity of acute COVID-19.Materials and methodsRetrospective multicenter data retrieval from 10 university medical centers in Germany, Switzerland and Austria between February 2020 and September 2021. We included patients with COVID-19, acute neurological symptoms and cranial imaging. We collected demographics, neurological symptoms, COVID-19 severity, results of cranial imaging, blood and CSF parameters during the hospital stay.Resul...
Source: Journal of Neurology - February 23, 2023 Category: Neurology Source Type: research

RCVS: by clinicians for clinicians —a narrative review
ConclusionIn general, the outcome of reversible cerebral vasoconstriction syndrome is very good. Vasospasm as well as thunderclap headache attacks can be fully reversible, and  >  90% of patients are functionally independent at discharge.
Source: Journal of Neurology - January 30, 2023 Category: Neurology Source Type: research

Association between intravenous tirofiban and intracranial hemorrhage in acute large vessel occlusion stroke: insight from the RESCUE BT randomized placebo-controlled trial
ConclusionsIn patients with acute large vessel occlusion stroke, intravenous tirofiban before EVT within 24  h of time from last known well is not associated with increased risk of SICH. Patients who are older, have more severe neurological deficits, or with cardioembolism are at higher risk of SICH with intravenous tirofiban.Trial registration numberURL:http://www.chictr.org.cn; Unique identifier: ChiCTR-INR-17014167.
Source: Journal of Neurology - January 25, 2023 Category: Neurology Source Type: research

The optimum anticoagulation time after endovascular thrombectomy for atrial fibrillation-related large vessel occlusion stroke: a real-world study
ConclusionsIn AF-related AIS, the time of EVT to anticoagulation is an independent factor of the functional outcome and hemorrhage events after anticoagulation. The optimal initiate time of anticoagulant after EVT is 4.5  days.ClinicalTrialRegisterNCT03754738.
Source: Journal of Neurology - January 3, 2023 Category: Neurology Source Type: research

Timed up-and-go performance is associated with objectively measured life  space in patients 3 months after ischemic stroke: a cross-sectional observational study
ConclusionThe TUG, an easily applicable bedside test, seems to be a useful indicator for patients ’ life space 3 months poststroke and may be a clinically useful measure to document the motor rehabilitative process.
Source: Journal of Neurology - December 22, 2022 Category: Neurology Source Type: research

Cerebral hemorrhage after thrombolysis in stroke patients with unruptured intracranial aneurysms: a systemic review and meta-analysis
ConclusionsIVT is unlikely to induce hemorrhage of pre-existing unruptured aneurysms in stroke patients. Further randomized control studies are warranted to validate these conclusions.Graphical abstract
Source: Journal of Neurology - December 22, 2022 Category: Neurology Source Type: research

White matter hyperintensities are an independent predictor of cognitive decline 3 years following first-ever stroke —results from the PROSCIS-B study
ConclusionHigher WMH burden was associated with a significant decline in cognition 3 years post-stroke in this cohort of first-ever stroke patients.
Source: Journal of Neurology - December 6, 2022 Category: Neurology Source Type: research

A rare cause of monogenic cerebral small vessel disease and stroke: Cathepsin A-related arteriopathy with strokes and leukoencephalopathy (CARASAL)
ConclusionsCARASAL should be considered in patients with early onset or severe cerebral small vessel disease, particularly where there are prominent symptoms or signs related to brainstem involvement, such as hearing dysfunction, tinnitus or dysphagia or where there is significant thalamic and brainstem involvement on imaging.
Source: Journal of Neurology - October 31, 2022 Category: Neurology Source Type: research

Clinical and neuroimaging risk factors associated with the development of intracerebral hemorrhage while taking direct oral anticoagulants
ConclusionsRisk factors including diabetes, prior stroke, and smoking history as well as MRI biomarkers including CMBs and cSS are associated with ICH in DOAC users. Although screening MRIs are not typically performed prior to initiating DOAC therapy, these data suggest that patients of high-hemorrhagic risk may be identified.
Source: Journal of Neurology - October 31, 2022 Category: Neurology Source Type: research

Prevalence, risk factors, and clinical outcomes of remote intracerebral hemorrhage after intravenous thrombolysis in acute ischemic stroke: a systematic review and meta-analysis
ConclusionsAlthough rICH is uncommon after intravenous thrombolysis, its presence can lead to worse functional outcomes and higher mortality in acute ischemic stroke. Patients at high risk of rICH must be identified based on potential risk factors.
Source: Journal of Neurology - October 5, 2022 Category: Neurology Source Type: research

Serum anti-NMDA-receptor antibodies and cognitive function after ischemic stroke (PROSCIS-B)
ConclusionIn our study, NMDAR1-abs seropositivity did not affect CF over 3  years after a first mild to moderate ischemic stroke. CF differed according to NMDAR1-abs serum titer, with patients with high NMDAR1-abs titers having a less favorable cognitive outcome compared to seronegative patients.
Source: Journal of Neurology - June 19, 2022 Category: Neurology Source Type: research

Carotid web: the challenging diagnosis of an under-recognized entity
ConclusionKnowledge of CW and differentiating it from atheroma plaques is essential, as medical management seems to be insufficient in many cases. Revascularization, which has been shown to be safe and effective, might be the best treatment modality.
Source: Journal of Neurology - June 17, 2022 Category: Neurology Source Type: research