Filtered By:
Source: European Heart Journal
Condition: Ischemic Stroke

This page shows you your search results in order of relevance. This is page number 2.

Order by Relevance | Date

Total 109 results found since Jan 2013.

Choosing a particular oral anticoagulant and dose for stroke prevention in individual patients with non-valvular atrial fibrillation: part 2
<span class="paragraphSection">The choice of oral anticoagulant (OAC) for patients with atrial fibrillation (AF) may be influenced by individual clinical features or by patterns of risk factors and comorbidities. We reviewed analyses of subgroups of patients from trials of vitamin K antagonists vs. non-vitamin K oral anticoagulants (NOACs) for stroke prevention in AF with the aim to identify patient groups who might benefit from a particular OAC more than from another. In addition, we discuss the timing of initiation of anticoagulation. In the second of a two-part review, we discuss the use of NOAC for stroke prevent...
Source: European Heart Journal - February 4, 2016 Category: Cardiology Source Type: research

Blood pressure and in-hospital outcomes in patients presenting with ischaemic stroke
ConclusionIn patients hospitalized with ischaemic stroke, J-shaped, or U-shaped relationships were observed between BP variables and short-term outcomes. However, haemorrhagic complications with thrombolytic therapy were lower with lower BP.
Source: European Heart Journal - June 30, 2017 Category: Cardiology Source Type: research

Diabetes and long-term outcomes of ischaemic stroke: findings from Get With The Guidelines-Stroke
ConclusionAmong older IS patients diabetes was associated with increased risks of death, cardiovascular and non-cardiovascular hospitalizations, HF, and IS/TIA recurrence.
Source: European Heart Journal - February 9, 2018 Category: Cardiology Source Type: research

Protective effects of angiopoietin-like 4 on cerebrovascular and functional damages in ischaemic stroke
Conclusion These results, therefore, show ANGPTL4 counteracts the loss of vascular integrity in ischaemic stroke, by restricting Src kinase signalling downstream from VEGFR2. ANGPTL4 treatment thus reduces oedema, infarct size, neuronal loss, and improves mice behaviour. These results suggest that ANGPTL4 constitutes a relevant target for vasculoprotection and cerebral protection during stroke.
Source: European Heart Journal - December 14, 2013 Category: Cardiology Authors: Bouleti, C., Mathivet, T., Coqueran, B., Serfaty, J.-M., Lesage, M., Berland, E., Ardidie-Robouant, C., Kauffenstein, G., Henrion, D., Lapergue, B., Mazighi, M., Duyckaerts, C., Thurston, G., Valenzuela, D. M., Murphy, A. J., Yancopoulos, G. D., Monnot, C Tags: BASIC SCIENCE Source Type: research

Anticoagulant vs. antiplatelet therapy in patients with cryptogenic stroke and patent foramen ovale: an individual participant data meta-analysis
Conclusion We did not find a statistically significant difference comparing OAC with APT; our results justify randomized trials comparing different antithrombotic approaches in these patients.
Source: European Heart Journal - September 14, 2015 Category: Cardiology Authors: Kent, D. M., Dahabreh, I. J., Ruthazer, R., Furlan, A. J., Weimar, C., Serena, J., Meier, B., Mattle, H. P., Di Angelantonio, E., Paciaroni, M., Schuchlenz, H., Homma, S., Lutz, J. S., Thaler, D. E. Tags: Thrombosis and antithrombotic therapy Source Type: research

Catheter ablation for atrial fibrillation is associated with lower incidence of stroke and death: data from Swedish health registries
Conclusion Ablation may be associated with lower incidence of ischaemic stroke and death in patients with AF. This beneficial finding appears more pronounced in patients with higher thromboembolic risk.
Source: European Heart Journal - August 23, 2016 Category: Cardiology Authors: Friberg, L., Tabrizi, F., Englund, A. Tags: Arrhythmia/electrophysiology Source Type: research

Transcatheter aortic valve thrombosis: the relation between hypo-attenuated leaflet thickening, abnormal valve haemodynamics, and stroke
Conclusion</div>On MDCT, 12.5% of patients showed HALT or reduced leaflet motion, whereas only one of these patients had abnormal valve haemodynamics on echocardiography. Neither HALT nor increased transvalvular gradient were associated with stroke/TIA.</span>
Source: European Heart Journal - March 27, 2017 Category: Cardiology Source Type: research

Duration of device-detected subclinical atrial fibrillation and occurrence of stroke in ASSERT
Conclusions</div>SCAF>24  h is associated with an increased risk of ischemic stroke or systemic embolism.</span>
Source: European Heart Journal - March 1, 2017 Category: Cardiology Source Type: research

Corrigendum to: Interdisciplinary management of acute ischaemic stroke: Current evidence training requirements for endovascular stroke treatment: Position Paper from the ESC Council on Stroke and the European Association for Percutaneous Cardiovascular Interventions with the support of the European Board of Neurointervention
Source: European Heart Journal - December 22, 2020 Category: Cardiology Source Type: research

Deletion of the ageing gene p66Shc reduces early stroke size following ischaemia/reperfusion brain injury
Conclusion In the present study, we show that the deletion of the ageing gene p66Shc protects mice from ischaemia/reperfusion brain injury through a blunted production of free radicals. The ROS mediator p66Shc may represent a novel therapeutical target for the treatment of ischaemic stroke.
Source: European Heart Journal - January 6, 2013 Category: Cardiology Authors: Spescha, R. D., Shi, Y., Wegener, S., Keller, S., Weber, B., Wyss, M. M., Lauinger, N., Tabatabai, G., Paneni, F., Cosentino, F., Hock, C., Weller, M., Nitsch, R. M., Luscher, T. F., Camici, G. G. Tags: FASTTRACK BASIC SCIENCE Source Type: research

Balancing stroke and bleeding risks in patients with atrial fibrillation and renal failure: the Swedish Atrial Fibrillation Cohort study
Conclusions Patients with both AF and renal failure will probably benefit most from having the same treatment as is recommended for other patients with AF, without setting a higher or lower threshold for treatment. Adding additional points for renal failure to the CHADS2 and CHA2DS2-VASc scores did not improve their predictive value.
Source: European Heart Journal - February 2, 2015 Category: Cardiology Authors: Friberg, L., Benson, L., Lip, G. Y. H. Tags: Atrial fibrillation Source Type: research

XANTUS: a real-world, prospective, observational study of patients treated with rivaroxaban for stroke prevention in atrial fibrillation
Conclusion XANTUS is the first international, prospective, observational study to describe the use of rivaroxaban in a broad NVAF patient population. Rates of stroke and major bleeding were low in patients receiving rivaroxaban in routine clinical practice. Trial registration number Clinicaltrials.gov: NCT01606995.
Source: European Heart Journal - April 6, 2016 Category: Cardiology Authors: Camm, A. J., Amarenco, P., Haas, S., Hess, S., Kirchhof, P., Kuhls, S., van Eickels, M., Turpie, A. G. G., the XANTUS Investigators Tags: Atrial fibrillation Source Type: research

Cost-effectiveness of apixaban vs. current standard of care for stroke prevention in patients with atrial fibrillation
Conclusions Based on randomized trial data, apixaban is a cost-effective alternative to warfarin and aspirin, in VKA suitable and VKA unsuitable patients with AF, respectively.
Source: European Heart Journal - July 21, 2014 Category: Cardiology Authors: Dorian, P., Kongnakorn, T., Phatak, H., Rublee, D. A., Kuznik, A., Lanitis, T., Liu, L. Z., Iloeje, U., Hernandez, L., Lip, G. Y. H. Tags: BASIC SCIENCE Source Type: research

Resumption of oral anticoagulation following traumatic injury and risk of stroke and bleeding in patients with atrial fibrillation: a nationwide cohort study
ConclusionAF patients resuming VKA and NOAC treatment following traumatic injury have lower hazard of all-cause mortality and ischaemic stroke, increased hazard of major bleeding but without additional hazards of recurrent traumatic injury. Withholding OAC following a traumatic injury in AF patients may not be warranted.
Source: European Heart Journal - November 18, 2017 Category: Cardiology Source Type: research

Serial assessment of biomarkers and the risk of stroke or systemic embolism and bleeding in patients with atrial fibrillation in the ENGAGE AF-TIMI 48 trial
ConclusionSerial assessment of hsTnT, NT-proBNP, and GDF-15 revealed that a substantial proportion of patients with AF had dynamic values. Greater increases in these biomarkers measured over 1 year are associated with important clinical outcomes in anticoagulated patients with AF.
Source: European Heart Journal - March 24, 2021 Category: Cardiology Source Type: research