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Source: JAHA:Journal of the American Heart Association
Condition: Stroke

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Total 368 results found since Jan 2013.

Implications of the US Cholesterol Guidelines on Eligibility for Statin Therapy in the Community: Comparison of Observed and Predicted Risks in the Framingham Heart Study Offspring Cohort Epidemiology
Conclusions The risk estimator overpredicted ASCVD risk but did so mainly among high-risk participants who would be considered eligible for statin use anyway. Our findings may mitigate concerns regarding the potential impact of miscalibration of the ASCVD estimator in contemporary cohorts.
Source: JAHA:Journal of the American Heart Association - April 17, 2015 Category: Cardiology Authors: Andersson, C., Enserro, D., Larson, M. G., Xanthakis, V., Vasan, R. S. Tags: Epidemiology Source Type: research

Race and Ethnicity, Obesity, Metabolic Health, and Risk of Cardiovascular Disease in Postmenopausal Women Epidemiology
Conclusions Metabolic abnormalities appeared to convey more cardiovascular risk among black women.
Source: JAHA:Journal of the American Heart Association - May 20, 2015 Category: Cardiology Authors: Schmiegelow, M. D., Hedlin, H., Mackey, R. H., Martin, L. W., Vitolins, M. Z., Stefanick, M. L., Perez, M. V., Allison, M., Hlatky, M. A. Tags: Epidemiology Source Type: research

Catheter Ablation of Atrial Fibrillation in U.S. Community Practice--Results From Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF) Arrhythmia and Electrophysiology
Conclusions In U.S. clinical practice, a minority of patients with AF are managed with catheter ablation. Subsequent to ablation, there were no significant differences in oral anticoagulation use or outcomes, including stroke/non–central nervous system embolism/transient ischemic attack or death. Clinical Trial Registration URL: http://www.clinicaltrials.gov. Unique identifier: NCT01165710.
Source: JAHA:Journal of the American Heart Association - May 21, 2015 Category: Cardiology Authors: Holmqvist, F., Simon, D., Steinberg, B. A., Hong, S. J., Kowey, P. R., Reiffel, J. A., Naccarelli, G. V., Chang, P., Gersh, B. J., Peterson, E. D., Piccini, J. P., the ORBIT-AF Investigators Tags: Arrhythmia and Electrophysiology Source Type: research

Increased Stiffness Is the Major Early Abnormality in a Pig Model of Severe Aortic Stenosis and Predisposes to Congestive Heart Failure in the Absence of Systolic Dysfunction Heart Failure
Conclusion Increased stiffness is the major early pathological process that predisposes to congestive heart failure without abnormalities in systolic function and relaxation in a clinically relevant animal model of aortic stenosis.
Source: JAHA:Journal of the American Heart Association - May 20, 2015 Category: Cardiology Authors: Ishikawa, K., Aguero, J., Oh, J. G., Hammoudi, N., A. Fish, L., Leonardson, L., Picatoste, B., Santos-Gallego, C. G., M. Fish, K., Hajjar, R. J. Tags: Heart Failure Source Type: research

Geographic Variations in Cardiovascular Health in the United States: Contributions of State- and Individual-Level Factors Epidemiology
Conclusions There is significant state-level variation in poor CVH that is partly explained by individual- and state-level factors. Additional longitudinal research is warranted to examine the influence of state-level policies and food and physical activity environments on poor CVH.
Source: JAHA:Journal of the American Heart Association - May 27, 2015 Category: Cardiology Authors: Gebreab, S. Y., Davis, S. K., Symanzik, J., Mensah, G. A., Gibbons, G. H., Diez-Roux, A. V. Tags: Epidemiology Source Type: research

Clinical Efficacy of Thrombus Aspiration on 5-Year Clinical Outcomes in Patients With ST-Segment Elevation Acute Myocardial Infarction Undergoing Percutaneous Coronary Intervention Interventional Cardiology
Conclusions Adjunctive TA during primary PCI was not associated with better 5-year mortality in STEMI patients.
Source: JAHA:Journal of the American Heart Association - June 15, 2015 Category: Cardiology Authors: Watanabe, H., Shiomi, H., Nakatsuma, K., Morimoto, T., Taniguchi, T., Furukawa, Y., Nakagawa, Y., Horie, M., Kimura, T., the CREDO-Kyoto AMI investigators, Kimura, T., Sakata, R., Marui, A., Matsuda, M., Mitsuoka, H., Onoe, M., Nakagawa, Y., Yamanaka, K., Tags: Interventional Cardiology Source Type: research

Seeking Culprit Lesions in Cryptogenic Stroke: The Utility of Vessel Wall Imaging Editorials
Source: JAHA:Journal of the American Heart Association - June 15, 2015 Category: Cardiology Authors: Sun, J., Yuan, C. Tags: Editorials Source Type: research

Traditional Risk Factors Versus Biomarkers for Prediction of Secondary Events in Patients With Stable Coronary Heart Disease: From the Heart and Soul Study Coronary Heart Disease
Conclusions Novel risk factors are superior to traditional risk factors for predicting 5-year risk of secondary events in patients with stable CHD.
Source: JAHA:Journal of the American Heart Association - July 6, 2015 Category: Cardiology Authors: Beatty, A. L., Ku, I. A., Bibbins-Domingo, K., Christenson, R. H., DeFilippi, C. R., Ganz, P., Ix, J. H., Lloyd-Jones, D., Omland, T., Sabatine, M. S., Schiller, N. B., Shlipak, M. G., Skali, H., Takeuchi, M., Vittinghoff, E., Whooley, M. A. Tags: Coronary Heart Disease Source Type: research

Association of 6-Minute Walk Performance and Physical Activity With Incident Ischemic Heart Disease Events and Stroke in Peripheral Artery Disease Vascular Medicine
Conclusions Six-minute walk and physical activity predict IHD event rates in PAD. Further study is needed to determine whether interventions that improve 6-minute walk, physical activity, or both can reduce IHD events in PAD.
Source: JAHA:Journal of the American Heart Association - July 28, 2015 Category: Cardiology Authors: McDermott, M. M., Greenland, P., Tian, L., Kibbe, M. R., Green, D., Zhao, L., Criqui, M. H., Guralnik, J. M., Ferrucci, L., Liu, K., Wilkins, J. T., Huffman, M. D., Shah, S. J., Liao, Y., Lloyd-Jones, D. M. Tags: Vascular Medicine Source Type: research

Risk of Incident Coronary Heart Disease Events in Men Compared to Women by Menopause Type and Race Epidemiology
Conclusions Sex differences in the risk of incident CHD events were larger among whites than blacks and varied by type of menopause. Women consistently had a lower risk of incident CHD death than men, but the magnitude of sex differences was greater in whites than blacks for nonfatal events, regardless of menopause type.
Source: JAHA:Journal of the American Heart Association - July 1, 2015 Category: Cardiology Authors: Kim, C., Cushman, M., Khodneva, Y., Lisabeth, L. D., Judd, S., Kleindorfer, D. O., Howard, V. J., Safford, M. M. Tags: Epidemiology Source Type: research

Cognitive Function: Is There More to Anticoagulation in Atrial Fibrillation Than Stroke? Contemporary Reviews
Source: JAHA:Journal of the American Heart Association - August 3, 2015 Category: Cardiology Authors: Cao, L., Pokorney, S. D., Hayden, K., Welsh-Bohmer, K., Newby, L. K. Tags: Contemporary Reviews Source Type: research

Outcome Reporting in Cardiac Surgery Trials: Systematic Review and Critical Appraisal Cardiovascular Surgery
Conclusions Outcome reporting in the cardiac surgery literature is heterogeneous, and efforts should be made to standardize the outcomes reported and the definitions used to ascertain them. The development of standardizing outcome reporting is an essential step toward strengthening the process of evidence-based care in cardiac surgery.
Source: JAHA:Journal of the American Heart Association - August 17, 2015 Category: Cardiology Authors: Goldfarb, M., Drudi, L., Almohammadi, M., Langlois, Y., Noiseux, N., Perrault, L., Piazza, N., Afilalo, J. Tags: Cardiovascular Surgery Source Type: research

Dabigatran is Less Effective Than Warfarin at Attenuating Mechanical Heart Valve-Induced Thrombin Generation Valvular Heart Disease
Conclusions MHV induce thrombin generation via the intrinsic pathway and generate sufficient thrombin to overwhelm clinically relevant dabigatran concentrations. In contrast, warfarin is more effective than dabigatran at suppressing MHV-induced thrombin generation. These data explain why dabigatran failed in MHV patients and suggest that strategies targeting FXII or FXI may suppress the root cause of thrombosis in such patients.
Source: JAHA:Journal of the American Heart Association - August 24, 2015 Category: Cardiology Authors: Jaffer, I. H., Stafford, A. R., Fredenburgh, J. C., Whitlock, R. P., Chan, N. C., Weitz, J. I. Tags: Valvular Heart Disease Source Type: research

Left Ventricular Structure and Risk of Cardiovascular Events: A Framingham Heart Study Cardiac Magnetic Resonance Study Epidemiology
Conclusions Among adults free of prevalent CVD in the community, greater LVMI and LV concentric hypertrophy are associated with a marked increase in adverse incident CVD events. The potential benefit of aggressive primary prevention to modify LV mass and geometry in these adults requires further investigation.
Source: JAHA:Journal of the American Heart Association - September 15, 2015 Category: Cardiology Authors: Tsao, C. W., Gona, P. N., Salton, C. J., Chuang, M. L., Levy, D., Manning, W. J., O'Donnell, C. J. Tags: Epidemiology Source Type: research

Long-Term Prognostic Risk in Lower Extremity Peripheral Arterial Disease as a Function of the Number of Peripheral Arterial Lesions Health Services and Outcomes Research
Conclusions Among PAD patients, a greater number of lesions is associated with an increased risk of an adverse prognosis over 3 years of follow-up. Assessing the number of lower extremity lesions might serve as a simple risk-stratification tool at initial PAD diagnosis.
Source: JAHA:Journal of the American Heart Association - October 26, 2015 Category: Cardiology Authors: Smolderen, K. G., van Zitteren, M., Jones, P. G., Spertus, J. A., Heyligers, J. M., Nooren, M. J., Vriens, P. W., Denollet, J. Tags: Health Services and Outcomes Research Source Type: research