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Source: JAHA:Journal of the American Heart Association
Condition: Stroke

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Total 368 results found since Jan 2013.

Contemporary Management of Atrial Fibrillation: What Can Clinical Registries Tell Us About Stroke Prevention and Current Therapeutic Approaches? Contemporary Reviews
Source: JAHA:Journal of the American Heart Association - August 27, 2014 Category: Cardiology Authors: Lip, G. Y. H., Al-Khatib, S. M., Cosio, F. G., Banerjee, A., Savelieva, I., Ruskin, J., Blendea, D., Nattel, S., De Bono, J., Conroy, J. M., Hess, P. L., Guasch, E., Halperin, J. L., Kirchhof, P., G. Cosio, M. D., Camm, A. J. Tags: Contemporary Reviews Source Type: research

Prognostic Value of Estimated Functional Capacity Incremental to Cardiac Biomarkers in Stable Cardiac Patients Coronary Heart Disease
Conclusion A simple self-assessment tool of functional capacity in stable patients undergoing elective diagnostic cardiac evaluation provides independent and incremental prognostic value for prediction of both significant coronary angiographic disease and long-term adverse clinical events.
Source: JAHA:Journal of the American Heart Association - October 20, 2014 Category: Cardiology Authors: Tang, W. H. W., Topol, E. J., Fan, Y., Wu, Y., Cho, L., Stevenson, C., Ellis, S. G., Hazen, S. L. Tags: Coronary Heart Disease Source Type: research

Short-Term Change in eGFR and Risk of Cardiovascular Events Health Services and Outcomes Research
Conclusion Clinically relevant changes in eGFR are associated with increased risk of cardiovascular events. However, most of the apparent increase in risk can be accounted for by assessing comorbidity and baseline kidney function.
Source: JAHA:Journal of the American Heart Association - September 11, 2014 Category: Cardiology Authors: Turin, T. C., James, M. T., Jun, M., Tonelli, M., Coresh, J., Manns, B. J., Hemmelgarn, B. R. Tags: Health Services and Outcomes Research Source Type: research

Importance of Exercise Capacity in Predicting Outcomes and Determining Optimal Timing of Surgery in Significant Primary Mitral Regurgitation Valvular Heart Disease
Conclusion In patients with primary MR that underwent exercise echocardiography followed by MV surgery, lower achieved metabolic equivalents were associated with worse long-term outcomes. In those with preserved exercise capacity, delaying MV surgery by ≥1 year did not adversely affect outcomes.
Source: JAHA:Journal of the American Heart Association - September 11, 2014 Category: Cardiology Authors: Naji, P., Griffin, B. P., Barr, T., Asfahan, F., Gillinov, A. M., Grimm, R. A., Rodriguez, L. L., Mihaljevic, T., Stewart, W. J., Desai, M. Y. Tags: Valvular Heart Disease Source Type: research

A Novel Protein Glycan Biomarker and Future Cardiovascular Disease Events Epidemiology
Conclusions In this prospective study of initially healthy women, baseline GlycA was associated with incident CVD, consistent with a possible role for protein glycans in inflammation and CVD. Clinical Trial Registration URL: http//clinicaltrials.gov/. Unique identifier NCT00000479.
Source: JAHA:Journal of the American Heart Association - September 23, 2014 Category: Cardiology Authors: Akinkuolie, A. O., Buring, J. E., Ridker, P. M., Mora, S. Tags: Epidemiology Source Type: research

Anti-Inflammatory Immune Skewing Is Atheroprotective: Apoe-/-Fc{gamma}RIIb-/- Mice Develop Fibrous Carotid Plaques Vascular Medicine
Conclusions We hypothesized that removal of FcRIIb would exacerbate atherosclerosis and generate unstable plaques. However, we found that deletion of FcRIIb on a congenic C57BL/6 background induces an anti-inflammatory Treg/M2 polarization that is atheroprotective.
Source: JAHA:Journal of the American Heart Association - December 16, 2014 Category: Cardiology Authors: Harmon, E. Y., Fronhofer, V., Keller, R. S., Feustel, P. J., Zhu, X., Xu, H., Avram, D., Jones, D. M., Nagarajan, S., Lennartz, M. R. Tags: Vascular Medicine Source Type: research

Habitual Sleep Duration and Predicted 10-Year Cardiovascular Risk Using the Pooled Cohort Risk Equations Among US Adults Epidemiology
Conclusions Mean-predicted 10-year cardiovascular risk was lowest among adults who reported sleeping 7 hours per night and increased as participants reported sleeping fewer and more hours.
Source: JAHA:Journal of the American Heart Association - December 2, 2014 Category: Cardiology Authors: Ford, E. S. Tags: Epidemiology Source Type: research

Cardiac Hemodynamics are Linked With Structural and Functional Features of Brain Aging: The Age, Gene/Environment Susceptibility (AGES)-Reykjavik Study Epidemiology
Conclusions A graded decrease in cardiac functioning is associated with features of brain aging. Older persons with cardiac or cognitive signs and symptoms may have both cardiac and cerebral diseases and should be evaluated accordingly.
Source: JAHA:Journal of the American Heart Association - January 27, 2015 Category: Cardiology Authors: Sabayan, B., van Buchem, M. A., Sigurdsson, S., Zhang, Q., Harris, T. B., Gudnason, V., Arai, A. E., Launer, L. J. Tags: Epidemiology Source Type: research

Neurological Complications and Outcomes in the Berlin Heart EXCOR(R) Pediatric Investigational Device Exemption Trial Pediatric Cardiology
Conclusions Of children treated with the Berlin Heart EXCOR® device as a bridge to transplant, 29% experienced at least 1 neurological event. The majority of neurological events were ischemic strokes, and many of those occurred early in the course of support. Neurological injury was the leading cause of death after implantation of the Berlin Heart EXCOR® device. Risk stratification for stroke or neurological injury is not possible based on baseline preimplantation characteristics. Clinical Trial Registration URL: www.clinicaltrials.gov. Unique Identifier: NCT00583661.
Source: JAHA:Journal of the American Heart Association - January 22, 2015 Category: Cardiology Authors: Jordan, L. C., Ichord, R. N., Reinhartz, O., Humpl, T., Pruthi, S., Tjossem, C., Rosenthal, D. N. Tags: Pediatric Cardiology Source Type: research

Lower Mortality Rate in Elderly Patients With Community-Onset Pneumonia on Treatment With Aspirin Epidemiology
Conclusions This study shows that chronic aspirin use is associated with lower mortality rate within 30 days after hospital admission in a large cohort of patients with pneumonia.
Source: JAHA:Journal of the American Heart Association - January 6, 2015 Category: Cardiology Authors: Falcone, M., Russo, A., Cangemi, R., Farcomeni, A., Calvieri, C., Barilla, F., Scarpellini, M. G., Bertazzoni, G., Palange, P., Taliani, G., Venditti, M., Violi, F. Tags: Epidemiology Source Type: research

Clinical Correlates and Prognostic Significance of Change in Standardized Left Ventricular Mass in a Community-Based Cohort of African Americans Epidemiology
Conclusions In our community-based sample of African Americans, baseline BMI and BP, and change in BP on follow-up were key determinants of increase in standardized log-LVMI, which in turn carried an adverse prognosis, underscoring the need for greater control of BP and weight in this group.
Source: JAHA:Journal of the American Heart Association - February 5, 2015 Category: Cardiology Authors: Fox, E. R., Musani, S. K., Samdarshi, T. E., Taylor, J. K., Beard, W. L., Sarpong, D. F., Xanthakis, V., McClendon, E. E., Liebson, P. R., Skelton, T. N., Butler, K. R., Mosley, T. H., Taylor, H., Vasan, R. S. Tags: Epidemiology Source Type: research

Predictors of Long-term Clinical Endpoints in Patients With Refractory Angina Coronary Heart Disease
Conclusions Clinically stable patients with RA who are medically managed have a modest mortality, but a high incidence of hospitalization and resource use over 3 years. These findings point to the need for novel therapies aimed at symptom mitigation in this population and their potential impact on health care utilization and costs.
Source: JAHA:Journal of the American Heart Association - January 30, 2015 Category: Cardiology Authors: Povsic, T. J., Broderick, S., Anstrom, K. J., Shaw, L. K., Ohman, E. M., Eisenstein, E. L., Smith, P. K., Alexander, J. H. Tags: Coronary Heart Disease Source Type: research

Alternative Calculations of Individual Patient Time in Therapeutic Range While Taking Warfarin: Results From the ROCKET AF Trial Arrhythmia and Electrophysiology
Conclusions TTR, the standard measure of control of warfarin anticoagulation, depends on imputing daily INR values for the vast majority of follow-up days. Our TTR calculation method may better reflect the impact of warfarin dose changes than the Rosendaal approach. In the ROCKET AF trial, this dose change–based approach led to a modest increase in overall mean iTTR but did not materially affect the large inter-regional differences previously reported. Clinical Trial Registration URL: ClinicalTrials.gov. Unique identifier: NCT00403767.
Source: JAHA:Journal of the American Heart Association - March 3, 2015 Category: Cardiology Authors: Singer, D. E., Hellkamp, A. S., Yuan, Z., Lokhnygina, Y., Patel, M. R., Piccini, J. P., Hankey, G. J., Breithardt, G., Halperin, J. L., Becker, R. C., Hacke, W., Nessel, C. C., Mahaffey, K. W., Fox, K. A. A., Califf, R. M., for the ROCKET AF Investigators Tags: Arrhythmia and Electrophysiology Source Type: research

American Heart Association's Life's Simple 7 and Risk of Venous Thromboembolism: The Reasons for Geographic and Racial Differences in Stroke (REGARDS) Study Epidemiology
Conclusions Life's Simple 7, a CVH metric, was associated with reduced VTE risk. Findings suggest that efforts to improve the population's CVH may reduce VTE incidence.
Source: JAHA:Journal of the American Heart Association - February 27, 2015 Category: Cardiology Authors: Olson, N. C., Cushman, M., Judd, S. E., McClure, L. A., Lakoski, S. G., Folsom, A. R., Safford, M. M., Zakai, N. A. Tags: Epidemiology Source Type: research

Patient Outcomes According to Adherence to Treatment Guidelines for Rhythm Control of Atrial Fibrillation Coronary Heart Disease
Conclusions Adherence to published guidelines in the antiarrhythmic management of AF is associated with improved patient outcomes.
Source: JAHA:Journal of the American Heart Association - April 6, 2015 Category: Cardiology Authors: Qin, D., Leef, G., Alam, M. B., Rattan, R., Munir, M. B., Patel, D., Khattak, F., Vaghasia, N., Adelstein, E., Jain, S. K., Saba, S. Tags: Coronary Heart Disease Source Type: research