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Source: The American Journal of Medicine
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Total 259 results found since Jan 2013.
Stroke and Bleeding Risk Co-distribution in Real-world Patients with Atrial Fibrillation: The Euro Heart Survey
The choice to recommend antithrombotic therapy to patients with atrial fibrillation should rely on cardioembolic and bleeding risk stratification. Sharing some risk factors, schemes to predict thrombotic and bleeding risk are expected not to be independent, yet the degree of their association has never been clearly quantified.
Source: The American Journal of Medicine - May 13, 2014 Category: Journals (General) Authors: Maura Marcucci, Gregory Y.H. Lip, Robby Nieuwlaat, Ron Pisters, Harry J.G.M. Crijns, Alfonso Iorio Tags: Clinical research study Source Type: research
Atrial Fibrillation and Stroke: Epidemiology
Source: The American Journal of Medicine - April 1, 2014 Category: Journals (General) Authors: James A. Reiffel Tags: CME multimedia activities Source Type: research
Trends in Stroke Rates, Risk, and Outcomes in the United States, 1988 to 2008
Source: The American Journal of Medicine - March 26, 2014 Category: Journals (General) Authors: Margaret C. Fang, Marcelo Coca Perraillon, Kaushik Ghosh, David M. Cutler, Allison B. Rosen Tags: Clinical research studies Source Type: research
Secondary Prevention after Ischemic Stroke or Transient Ischemic Attack
Source: The American Journal of Medicine - March 26, 2014 Category: Journals (General) Authors: Sripal Bangalore, Lee Schwamm, Eric E. Smith, Inder M. Singh, Li Liang, Gregg C. Fonarow, Deepak L. . Bhatt, Get With the Guidelines-Stroke Steering Committee and Investigators Source Type: research
Trends in Stroke Rates, Risk, and Outcomes in the United States, 1988-2008
Source: The American Journal of Medicine - March 25, 2014 Category: Journals (General) Authors: Margaret C. Fang, Marcelo Coca Perraillon, Kaushik Ghosh, David M. Cutler, Allison B. Rosen Source Type: research
AFib in Special Populations
Abstract: For physicians who see and treat patients who present with AFib in routine clinical practice there are 4 important factors to understand and bear in mind when diagnosing and planning treatment strategies: age, gender, prior or incident heart failure, and underlying coronary artery disease (CAD) and acute coronary syndrome (ACS). (online video available at: http://education.amjmed.com/video.php?event_id=445&stage_id=5&vcs=1). This review addresses the clinical characteristics of each of these presentations in order. For all patients with AFib, of either gender or any age, the greatest risk is failure to prescrib...
Source: The American Journal of Medicine - March 24, 2014 Category: Journals (General) Authors: William J. French Tags: CME multimedia activities Source Type: research
Atrial Fibrillation and Stroke: Epidemiology
Abstract: The statistics for AFib are impressive. (online video available at: http://education.amjmed.com/video.php?event_id=445&stage_id=5&vcs=1). The principal risk with AFib, stroke or thrombotic embolism, is increased 5-fold in some series; AFib accounts for ≥15% of all strokes in the United States, 36% of strokes for individuals aged>80, and up to 20% of cryptogenic strokes, which means>100,000–125,000 embolic strokes per year, of which>20% are fatal. Patients with ischemic stroke and AFib are significantly (P
Source: The American Journal of Medicine - March 24, 2014 Category: Journals (General) Authors: James A. Reiffel Tags: CME multimedia activities Source Type: research
AFib Treatment: General Population
Abstract: When primary care physicians are presented with a patient with atrial fibrillation (AFib), there are two concerns. (online video available at: http://education.amjmed.com/video.php?event_id=445&stage_id=5&vcs=1). One is the choice of strategy to treat the AFib, ie, whether to use rate control or a rhythm control strategy (to keep patients in sinus rhythm). The second concern is preventing the principal risk associated with AFib: stroke and systemic embolism. The focus of this review is stroke prevention, concentrating on risk assessment and traditional versus the new oral anticoagulation agents. For the past se...
Source: The American Journal of Medicine - March 24, 2014 Category: Journals (General) Authors: Steven A. Rothman Tags: CME multimedia activities Source Type: research
Novel Oral Anticoagulants
Abstract: Warfarin has a proven record as an oral anticoagulant; almost every study, however, has found that it is not prescribed for 40–60% of patients who are eligible and should receive it, and of those who do receive it, serum warfarin levels only achieved a time in therapeutic range (TTR) equal to INR 2–3 about 55–60% of the time (online video available at: http://education.amjmed.com/video.php?event_id=445&stage_id=5&vcs=1). This means that only about 1 in 4 patients are adequately anticoagulated with warfarin, and thus there is a large unmet need for achieving better anticoagulation in these patients. Although...
Source: The American Journal of Medicine - March 24, 2014 Category: Journals (General) Authors: James A. Reiffel Tags: CME multimedia activities Source Type: research
New versus Traditional Approaches to Oral Anticoagulation in Patients with Atrial Fibrillation
Abstract: For clinicians, atrial fibrillation (AFib) is not a disease that will probably be “cured” at some point during their professional lifetime. (online video available at: http://education.amjmed.com/video.php?event_id=445&stage_id=5&vcs=1). AFib is a condition that occurs in association with aging, affecting as many as 1 in 10 patients by the time they reach age 85, and therefore all physicians who read The American Journal of Medicine should be aware of AFib—its etiology, how to recognize it, and with some idea of how it is treated. Perhaps the most important aspect of AFib, however, is as a risk factor for...
Source: The American Journal of Medicine - March 24, 2014 Category: Journals (General) Authors: James A. Reiffel Tags: CME multimedia activities Source Type: research
Treat or Eat: Food Insecurity, Cost-related Medication Underuse, and Unmet Needs
Conclusions: Approximately 1 in 3 chronically ill NHIS participants are unable to afford food, medications, or both. WIC and public health insurance participation are associated with less food insecurity and cost-related medication underuse.
Source: The American Journal of Medicine - January 21, 2014 Category: Journals (General) Authors: Seth A. Berkowitz, Hilary K. Seligman, Niteesh K. Choudhry Tags: Clinical research studies Source Type: research
CHA2DS2-VASc Score Is Directly Associated with the Risk of Pulmonary Embolism in Patients with Atrial Fibrillation
Conclusions: CHA2DS2-VASc score is directly associated with the incidence of pulmonary embolism in atrial fibrillation.
Source: The American Journal of Medicine - January 1, 2014 Category: Journals (General) Authors: Walid Saliba, Gad Rennert Tags: Clinical research studies Source Type: research
A ‘Posterior Circulation Stroke’ that Benefits from Vitamins
A 75-year-old woman was admitted for somnolence and confusion. She had been treated for hypertension and hyperlipidemia. One year before, she had been hospitalized for a mild right ataxic hemiparesis attributed to a lacunar stroke and received aspirin 100 mg/day. For the past 6 months, she regularly complained about gastric discomfort and bloating, which was attributed to the aspirin intake. As a consequence of her gastric problems and her decreasing appetite, her food intake was very limited. During a call, 24 hours before admission, she complained about nausea and vomiting for the past 2 days; she felt dizzy and staggere...
Source: The American Journal of Medicine - December 13, 2013 Category: Journals (General) Authors: Theodoros Karapanayiotides, Athanasia Anastasiou, Nikolaos Barmpas, Nikolaos Grigoriadis, Dimitrios Karacostas Tags: Clinical communications to the editor Source Type: research
Prevalence of Hyponatremia and Association with Mortality: Results from NHANES
Abstract: Background: Hyponatremia is the most common electrolyte abnormality in hospitalized patients and is associated with adverse outcomes, but its prevalence and significance in the general US population is unknown. Our aims were to determine the prevalence of hyponatremia and its association with mortality in the population.Methods: We performed a population-based, cross-sectional study of 14,697 adults aged ≥18 years who participated in the nationally representative National Health and Nutrition Examination Survey for 1999-2004. By using measurements of serum sodium corrected for dilutional effect of hyperglycemia...
Source: The American Journal of Medicine - November 27, 2013 Category: Journals (General) Authors: Sumit Mohan, Sue Gu, Amay Parikh, Jai Radhakrishnan Tags: Clinical research studies Source Type: research
Early Invasive Versus Initial Conservative Treatment Strategies in Octogenarians with UA/NSTEMI
Abstract: Background: Previous studies have demonstrated improved outcomes with an early invasive strategy in patients with unstable angina/non-ST-elevation myocardial infarction (UA/NSTEMI). However, there are limited data for patients ≥80 years of age in these studies.Methods: We used the 2003-2010 Nationwide Inpatient Sample databases to identify all patients ≥80 years of age (octogenarians) with UA/NSTEMI. Multivariable logistic regression was used to compare in-hospital outcomes in octogenarians with UA/NSTEMI undergoing early invasive (coronary angiography within 48 hours of admission, with or without revasculari...
Source: The American Journal of Medicine - November 27, 2013 Category: Journals (General) Authors: Dhaval Kolte, Sahil Khera, Chandrasekar Palaniswamy, Marjan Mujib, Gregg C. Fonarow, Ali Ahmed, Diwakar Jain, William H. Frishman, Wilbert S. Aronow Tags: Clinical research studies Source Type: research
