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Source: The American Journal of Medicine

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Total 259 results found since Jan 2013.

The Diabetes Shared Care Program and Risks of Cardiovascular Events in Type 2 Diabetes
The Diabetes Shared Care Program (DSCP) is an integrated diabetes care model designed to increase the quality of diabetes care in Taiwan. The efficacy of this program is unknown. Therefore, we evaluated whether participating patients had reduced risks of cardiovascular events, including coronary heart disease, stroke, and all-cause mortality.
Source: The American Journal of Medicine - April 20, 2015 Category: Journals (General) Authors: Edy Kornelius, Jeng-Yuan Chiou, Yi-Sun Yang, Ying-Li Lu, Chiung-Huei Peng, Chien-Ning Huang Tags: Clinical Research Study Source Type: research

Misconceptions and Facts about Atrial Fibrillation
Atrial fibrillation is an increasingly common arrhythmia associated with substantial but largely preventable risk of ischemic stroke. There has been an exponential increase in research related to atrial fibrillation in recent years resulting in some major advances in the therapeutic management. Novel oral anticoagulant agents have become available and require thorough assessment of risk benefit ratio. While the knowledge is rapidly accumulating the basic principles of atrial fibrillation management remain proper recognition, risk stratification, and appropriate prevention of thromboembolic complications.
Source: The American Journal of Medicine - March 28, 2015 Category: Journals (General) Authors: Edgar Argulian, David Conen, Franz H. Messerli Tags: Review Source Type: research

Apparent Treatment-Resistant Hypertension among Individuals with History of Stroke or Transient Ischemic Attack
and Purpose. Blood pressure control is a paramount goal in secondary stroke prevention; however, high prevalence of uncontrolled blood pressure and use of multiple antihypertensive medication classes in stroke patients suggest this goal is not being met. We determined the prevalence and factors associated with apparent treatment-resistant hypertension in persons with/without stroke or transient ischemic attack..
Source: The American Journal of Medicine - March 11, 2015 Category: Journals (General) Authors: Virginia J. Howard, Rikki M. Tanner, Aaron Anderson, Marguerite R. Irvin, David A. Calhoun, Daniel T. Lackland, Suzanne Oparil, Paul Muntner Source Type: research

Obstructive Sleep Apnea: A New Preventive and Therapeutic Target for Stroke
Stroke is the second leading cause of death worldwide and a major cause of mental and physical impairment. Numerous studies have identified risk factors for stroke, including hypertension, atrial fibrillation, diabetes, and smoking. However, even after considering these well-recognized risk factors, there is substantial variation in stroke rates and stroke-related outcomes. There is emerging evidence that obstructive sleep apnea increases the risk of stroke independently of traditional risk factors.
Source: The American Journal of Medicine - February 28, 2015 Category: Journals (General) Authors: Vahid Mohsenin Tags: Review Source Type: research

Obstructive Sleep Apnea: A New Preventive and Therapeutic Target for Stroke A new kid on the block
Stroke is the second leading cause of death worldwide and a major cause of mental and physical impairment. Numerous studies have identified risk factors for stroke, including hypertension, atrial fibrillation, diabetes, and smoking. However, even after considering these well-recognized risk factors, there is substantial variation in stroke rates and stroke-related outcomes. There is emerging evidence that obstructive sleep apnea increases the risk of stroke independent of traditional risk factors.
Source: The American Journal of Medicine - February 28, 2015 Category: Journals (General) Authors: Vahid Mohsenin Source Type: research

Quality of Care: A Long Way to Tipperary or a Long Way Down
Bangalore et al1 concluded that the quality of care for secondary prevention of stroke at discharge was “lower after transient ischemic attack (TIA) than after ischemic stroke.” This deserves comments.
Source: The American Journal of Medicine - February 22, 2015 Category: Journals (General) Authors: Alain Braillon Tags: AJM online Source Type: research

The Reply
Braillon contends that we should have stressed the poor and unacceptable levels of quality of care for ischemic stroke, which was even worse for transient ischemic attack. We do not agree that the quality of care for ischemic stroke was unacceptable and poor.
Source: The American Journal of Medicine - February 22, 2015 Category: Journals (General) Authors: Sripal Bangalore, Lee Schwamm, Eric E. Smith, Inder M. Singh, Li Liang, Gregg C. Fonarow, Deepak L. Bhatt, Get With the Guidelines-Stroke Steering Committee and Investigators Tags: AJM online Source Type: research

Totally one-sided: painless unilateral proptosis
An 88-year-old woman’s startling ophthalmologic symptoms were wrongly attributed to infection during an outpatient examination. When treatment offered no improvement, she presented to Johns Hopkins Hospital, where she reported progressive left eye swelling of 2 weeks’ duration. Seven years earlier, she had undergone mastectomy, chemotherapy, and radiation for breast cancer. Her medical history was also significant for a prior stroke, hypertension, and dementia.
Source: The American Journal of Medicine - January 5, 2015 Category: Journals (General) Authors: Bharati Kochar, Shannon J.C. Shan, Gobind Anand, S. James Zinreich, Allan C. Gelber Source Type: research

Predictors of intraoperative hypotension and bradycardia
Perioperative hypotension and bradycardia in the surgical patient is associated with adverse outcomes including stroke. We developed and evaluated a new preoperative risk model in predicting intraoperative hypotension or bradycardia in patients undergoing elective non-cardiac surgery.
Source: The American Journal of Medicine - December 22, 2014 Category: Journals (General) Authors: Christopher Cheung, Alan Martyn, Norman Campbell, Shaun Frost, Kenneth Gilbert, Franklin Michota, Douglas Seal, William Ghali, Nadia Khan Source Type: research

Antiphospholipid syndrome: an important differential diagnosis for culture-negative endocarditis
Sometimes the initial diagnosis proves secondary to an illness that is diagnosed later. This was the case when a 37-year-old woman presented to the hospital with sudden-onset persistent left-sided weakness. While she reported pain in the right maxilla, lethargy, and malaise in the month prior to presentation, she denied headache, sensory change, visual disturbances, fever, chills or weight loss. Hypertension was her only cardiovascular risk factor, but she took no regular medications. She had no history of stroke, ischemic heart disease, deep vein thrombosis, pulmonary embolism, or miscarriage, and she had no family histor...
Source: The American Journal of Medicine - November 26, 2014 Category: Journals (General) Authors: Louis W. Wang, Baptiste Noël, Elodie Descloux, David W. Baron Source Type: research

The Association between Red Cell Distribution Width and Stroke in Patients with Atrial Fibrillation
Red cell distribution width is associated with increased risk of cardiovascular morbidity and mortality. We aimed to assess its association with stroke in patients with atrial fibrillation.
Source: The American Journal of Medicine - October 14, 2014 Category: Journals (General) Authors: Walid Saliba, Ofra Barnett-Griness, Mazen Elias, Gad Rennert Source Type: research

Dabigatran and warfarin for secondary prevention of stroke in atrial fibrillation patients: A nationwide cohort study
This study revealed, that in clinical practice, vitamin K antagonist-experienced patients with a history of stroke or transient ischemic attack who switch to dabigatran therapy may have an increased rate of a recurrent stroke compared to patients persisting with vitamin K antagonist therapy.
Source: The American Journal of Medicine - September 1, 2014 Category: Journals (General) Authors: Torben Bjerregaard Larsen, Lars Hvilsted Rasmussen, Anders Gorst-Rasmussen, Flemming Skjøth, Deirdre A. Lane, Gregory Y.H. Lip Source Type: research

Cognitive impairment is associated with medication nonadherence in asymptomatic carotid stenosis
Adherence to medical management of vascular risk is vital for stroke prevention in patients with asymptomatic carotid stenosis. Since carotid disease is a risk factor for cognitive impairment, we sought to determine if undiagnosed cognitive impairment impacts medication adherence in this setting.
Source: The American Journal of Medicine - August 26, 2014 Category: Journals (General) Authors: Angelia C. Kirkpatrick, Andrea S. Vincent, Leslie Guthery, Calin I. Prodan Source Type: research

Cholesterol Management in Older Persons
Most atherosclerotic cardiovascular disease consists of coronary heart disease and stroke, and most atherosclerotic cardiovascular disease occurs in older persons. Randomized clinical trials with cholesterol-lowering drugs, notably statins, show reduced atherosclerotic cardiovascular disease events (1,2). Statins are indicated when atherosclerotic cardiovascular disease is present. They further reduce risk in primary prevention including older persons (1,2). But their indications in primary prevention are less well defined than for secondary prevention.
Source: The American Journal of Medicine - August 19, 2014 Category: Journals (General) Authors: Scott M. Grundy Source Type: research

Coexistence of Intracranial Atherosclerosis and Nonvalvular Atrial Fibrillation
When atrial fibrillation is “food for thought” in the etiopathogenesis of stroke and dementia,1 this also should be an opportunity to identify common ground between atrial fibrillation and intracranial atherosclerosis,2 given the fact that both disorders are age related, and also have similar risk factors and similar outcomes.1,2
Source: The American Journal of Medicine - August 1, 2014 Category: Journals (General) Authors: Oscar M.P. Jolobe Tags: Letters Source Type: research