Filtered By:
Source: The American Journal of Medicine

This page shows you your search results in order of date. This is page number 10.

Order by Relevance | Date

Total 259 results found since Jan 2013.

Renal function considerations for stroke prevention in atrial fibrillation
Renal impairment increases risk of stroke and systemic embolic events and bleeding in patients with atrial fibrillation. Direct oral anticoagulants have varied dependence on renal elimination, magnifying the importance of appropriate patient selection, dosing, and periodic kidney function monitoring. In randomized controlled trials of nonvalvular atrial fibrillation, direct oral anticoagulants were at least as effective and associated with less bleeding compared with warfarin. Each direct oral anticoagulant was associated with reduced risk of stroke and systemic embolic events and major bleeding compared with warfarin in n...
Source: The American Journal of Medicine - May 11, 2017 Category: General Medicine Authors: John Fanikos, Allison E. Burnett, Charles E. Mahan, Paul P. Dobesh Tags: Review Source Type: research

Diagonal Earlobe Crease Frank's Sign - a Predictor of Cerebral Vascular Events
Frank's sign was first described in 1973 by an American physician (T. Frank). It is a diagonal crease in the earlobe which starts from the tragus to the edge of the auricle in an angle of 45 degrees in varying depths. Frank sign was described as a predictor of future coronary heart disease and peripheral vascular diseases. The aim of the study was to examine the association between Frank sign and the development of ischemic stroke.
Source: The American Journal of Medicine - April 28, 2017 Category: Journals (General) Authors: Saleh Nazzal, Basem Hijazi, Luai Khalila, Arnon Blum Tags: Clinical Research Study Source Type: research

Diagonal Earlobe Crease (Frank's Sign): A Predictor of Cerebral Vascular Events
Frank's sign was first described in 1973 by an American physician (Sonders T. Frank). It is a diagonal crease in the earlobe that starts from the tragus to the edge of the auricle in an angle of 45 ° in varying depths. Frank's sign was described as a predictor of future coronary heart disease and peripheral vascular diseases. The aim of the study was to examine the association between Frank's sign and the development of ischemic stroke.
Source: The American Journal of Medicine - April 28, 2017 Category: General Medicine Authors: Saleh Nazzal, Basem Hijazi, Luai Khalila, Arnon Blum Tags: Clinical research study Source Type: research

Edoxaban: How Does the Newest Agent Fit into the DOAC Landscape?
Edoxaban is the most recently approved factor Xa inhibitor within the class of direct oral anticoagulants (DOACs). Like other DOACs, edoxaban was approved by the US Food and Drug Administration for treatment of venous thromboembolism and prevention of stroke in patients with nonvalvular atrial fibrillation. Similar to other DOACs, edoxaban has fewer drug –drug interactions than warfarin and does not require routine laboratory monitoring. Unlike other DOACs, edoxaban has yet to be approved for secondary or postoperative venous thromboembolism thromboprophylaxis.
Source: The American Journal of Medicine - April 5, 2017 Category: General Medicine Authors: Caitlin M. Gibson, Shannon W. Finks Tags: Review Source Type: research

Edoxaban: Defining place in therapy for the newest direct acting oral anticoagulant
Edoxaban is the most recently approved factor Xa inhibitor within the class of direct oral anticoagulants (DOACs). Like other DOACs, edoxaban was approved by the FDA for treatment of venous thromboembolism and prevention of stroke in patients with non-valvular atrial fibrillation. Similar to other DOACs, edoxaban has fewer drug-drug interactions than warfarin and does not require routine laboratory monitoring. Unlike other DOACs, edoxaban has yet to be approved for secondary or postoperative venous thromboembolism thromboprophylaxis.
Source: The American Journal of Medicine - April 5, 2017 Category: Journals (General) Authors: Caitlin M. Gibson, Shannon W. Finks Tags: Review Source Type: research

Viewpoint Stroke prevention in recent guidelines for the management of patients with atrial fibrillation: An appraisal
Formal guidelines play an important role in disseminating the best available evidence knowledge and are expected to provide simple and practical recommendations for the most optimal management of patients with various conditions. Such guidelines have important implications for many disease states, which thereby could be more professionally managed in everyday clinical practice by clinicians with divergent educational backgrounds, and also more easily implemented in wards or outpatient clinics eliminating inequalities in health care management.
Source: The American Journal of Medicine - March 23, 2017 Category: Journals (General) Authors: Tatjana S. Potpara, Gregory Y.H. Lip, Carina Blomstr öm Lundqvist, Chern-En Chiang, A. John Camm Tags: Review Source Type: research

Viewpoint: Stroke Prevention in Recent Guidelines for the Management of Patients with Atrial Fibrillation: An Appraisal
Formal guidelines play an important role in disseminating the best available evidence knowledge and are expected to provide simple and practical recommendations for the most optimal management of patients with various conditions. Such guidelines have important implications for many disease states, which thereby could be more professionally managed in everyday clinical practice by clinicians with divergent educational backgrounds, and also more easily implemented in wards or outpatient clinics, eliminating inequalities in health care management.
Source: The American Journal of Medicine - March 23, 2017 Category: Journals (General) Authors: Tatjana S. Potpara, Gregory Y.H. Lip, Carina Blomstr öm-Lundqvist, Chern-En Chiang, A. John Camm Tags: Review Source Type: research

Double the Trouble: Acute Coronary Syndrome and Ischemic Stroke in Polycythemia Vera
Vague symptoms turned out to be life-threatening conditions. A 50 year-old man with a history of polycythemia vera, presented to hospital with epigastric discomfort and clumsiness of the right hand for 5 days. Polycythemia vera was diagnosed 1 year prior with good control of hematocrit by intermittent phlebotomy. He did not have any other medical history, and was not taking any medications. He denied chest pain, shortness of breath, nausea, headache, vision change, or speech difficulty.
Source: The American Journal of Medicine - March 12, 2017 Category: Journals (General) Authors: Hitomi Hosoya, Jeffrey J. Levine, David H. Henry, Sheldon Goldberg Tags: Diagnostic Dilemma Source Type: research

The Reply
Arunachalam suggests that describing the reasons for readmissions might help in determining how to improve patient care. We agree, and this was our rationale for determining diagnosis syndromes for each patient.1 Overall, the increases in readmissions were observed across all diagnoses and accentuated for patients with stroke or delirium (Figure). This means that hospital admissions may also be influenced by other determinants of health.
Source: The American Journal of Medicine - February 17, 2017 Category: Journals (General) Authors: Christopher J. Yarnell, Steven Shadowitz, Donald A. Redelmeier Tags: AJM online Source Type: research

Wunderlich Syndrome
A 55-year-old man presented to the Emergency Department with severe abdominal pain for 1 day. He had a history of hypertension, diabetes mellitus, and ischemic stroke. The pain was severe, sharp, and constant, in his left flank; it woke him up from sleep and radiated to the mid back. On physical examination, his vital signs were stable and he had tenderness over the left flank. However, he developed hypotension, with mean arterial pressures dropping to 55  mm Hg and lactic acidosis requiring aggressive volume resuscitation.
Source: The American Journal of Medicine - January 30, 2017 Category: Journals (General) Authors: Aron Simkins, Abhishek Maiti, Sujith V. Cherian Tags: Clinical communication to the editor Source Type: research

Salt, Tomato Soup, and the Hypocrisy of the American Heart Association
In no uncertain terms did the American Heart Association (AHA)1 condemn a recent study by Mente et  al2 in The Lancet: “The findings in this study are not valid” … “a flawed study” … “you shouldn't use it to inform yourself about how you're going to eat” read some of the statements in the AHA's comment. The study in question suggested that not only will salt restriction not benef it most people, but it may actually be harmful if salt intake becomes too low. In only about 11% of the more than 100,000 study population, in patients who had high blood pressure, did salt restriction help to lower the risk of he...
Source: The American Journal of Medicine - November 20, 2016 Category: Journals (General) Authors: Franz H. Messerli, Stefano F. Rimoldi, Sripal Bangalore Tags: Commentary Source Type: research

Salt, Tomato Soup and Hypocrisy of the American Heart Association
In no uncertain terms did the American Heart Association (AHA)[1] condemn a recent study by Mente et al. in the Lancet[2] : “The findings in this study are not valid” … “a flawed study”…” you shouldn’t use it to inform yourself about how you’re going to eat” read some of the statements in the AHA’s comment. The study in question suggested that salt restriction will only not benefit most people but m ay actually be harmful if salt intake becomes too low. Only in about 11% of the more than 100 000 study population, in patients who had high blood pressure, did salt restriction help to lower the risk of h...
Source: The American Journal of Medicine - November 20, 2016 Category: Journals (General) Authors: Franz H. Messerli, Stefano. F. Rimoldi, Sripal Bangalore Tags: Commentary Source Type: research

Silent Atrial Fibrillation and Cryptogenic Strokes
A new suspected cause of cryptic strokes is “silent atrial fibrillation”.Pacemakers and other implanted devices allow continuous recording of cardiac rhythm for months or years. They have discovered that short periods of atrial fibrillation lasting minutes or hours are frequent and usually are asymptomatic.A meta-analysis of 50 studies in volving more than 10,000 patients with a recent stroke found that 7.7% had atrial fibrillation on their admitting EKG. In 3 weeks during and after hospitalization, another 16.9% were diagnosed.
Source: The American Journal of Medicine - October 14, 2016 Category: Journals (General) Authors: James E. Dalen, Joseph S. Alpert Tags: Review Source Type: research

Non-vitamin K Antagonist Oral Anticoagulants for Cardioversion in Atrial Fibrillation – An Updated Meta-analysis
Non-vitamin K oral anticoagulants (NOACs) are now proven alternatives to vitamin K antagonists (VKAs) for stroke prevention in atrial fibrillation (AF). However, there are few data on the efficacy and safety of their use around cardioversion, where the risk of thromboembolic events is heightened.
Source: The American Journal of Medicine - October 13, 2016 Category: Journals (General) Authors: Giulia Renda, Fabrizio Ricci, Raffaele De Caterina Tags: Clinical Research Study Source Type: research

Non-Vitamin K Antagonist Oral Anticoagulants for Cardioversion in Atrial Fibrillation: An Updated Meta-analysis
Non-vitamin K oral anticoagulants are now proven alternatives to vitamin K antagonists for stroke prevention in atrial fibrillation. However, there are few data on the efficacy and safety of their use for cardioversion, in which the risk of thromboembolic events is heightened.
Source: The American Journal of Medicine - October 13, 2016 Category: Journals (General) Authors: Giulia Renda, Fabrizio Ricci, Raffaele De Caterina Tags: Clinical research study Source Type: research