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Cancer: Pancreatic Cancer
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Total 84 results found since Jan 2013.
Investigation of Pancreatic-beta cells Role in the Biological Process of Ageing
CONCLUSION: Aging accelerates beta cell senescence by generating premature cell senescence, which is mostly mediated by high glucose levels. Despite higher plasma glucose levels, hepatic gluconeogenesis accelerates and adipose tissue lipolysis rises, resulting in an increase in free fatty acid levels in the blood and worsening insulin resistance throughout the body.PMID:37608675 | DOI:10.2174/1871530323666230822095932
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - August 23, 2023 Category: Endocrinology Authors: Rishabh Chaudhary Janvi Khanna Manni Rohilla Sumeet Gupta Seema Bansal Source Type: research
Artificially sweetened beverages and health outcomes: an umbrella review
CONCLUSIONS: The consumption of ASBs was associated with a higher risk of obesity, type II diabetes, all-cause mortality, hypertension, and cardiovascular disease incidence. However, further cohort studies and clinical trials in humans are still needed to understand the impact of ASBs on health outcomes.PMID:37187453 | DOI:10.1016/j.advnut.2023.05.010
Source: Adv Data - May 15, 2023 Category: Epidemiology Authors: Cristina Diaz Leandro F M Rezende Angelo Sabag Dong Hoon Lee Gerson Ferrari Edward L Giovannucci Juan Pablo Rey-Lopez Source Type: research
SNHG11 ：A New Budding Star in Tumors and Inflammatory Diseases
CONCLUSION: LncRNA SNHG11 can serve as an early diagnostic biomarker, therapeutic target, and prognostic indicator in various diseases, particularly tumors. SNHG11 plays a crucial role in the occurrence and development of tumors and inflammatory diseases through various mechanisms, which has significant implications for clinical diagnosis and treatment.PMID:37165588 | DOI:10.2174/1389557523666230509122402
Source: Mini Reviews in Medicinal Chemistry - May 11, 2023 Category: Chemistry Authors: Yinxin Wu Source Type: research
Clinical characteristics of pancreatic and biliary tract cancers in Lynch syndrome: A retrospective analysis from the Finnish National Lynch Syndrome Research Registry
ConclusionAlthough the survival of LS patients with PC or BTC is better than in sporadic cancers, it is still poor and may be reflected by the relatively higher surgical resectability accounted for by the earlier age of onset. More studies on analyses of the molecular and immune profile, screening, and management of LS-associated pancreaticobiliary cancers are warranted.
Source: Frontiers in Oncology - February 1, 2023 Category: Cancer & Oncology Source Type: research
A review on the role of MEG8 lncRNA in human disorders
Cancer Cell Int. 2022 Sep 16;22(1):285. doi: 10.1186/s12935-022-02705-9.ABSTRACTMaternally expressed 8 (MEG8) is a long non-coding RNA which is expressed in the nucleus. It is highly expressed in adrenal, placenta and brain. Recent studies have shown contribution of MEG8 in different disorders ranging from neoplastic ones to diabetic nephropathy, atherosclerosis, ischemic stroke, trophoblast dysfunction and abortion, Henoch-Schonlein purpura and osteoarthritis. It has an oncogenic role in the development of lung, pancreatic and liver cancer. In the current review, we summarize the role of this lncRNA in mentioned disorders...
Source: Atherosclerosis - September 16, 2022 Category: Cardiology Authors: Soudeh Ghafouri-Fard Tayyebeh Khoshbakht Bashdar Mahmud Hussen Mohammad Taheri Seyedpouzhia Shojaei Source Type: research
MR Three-Territory Sign in Cancer-Associated Hypercoagulation Stroke (Trousseau Syndrome): An Overlooked Diagnostic Feature: MR Three-Territory Sign
Conclusion:
TTS is a frequently missed diagnostic magnetic resonance feature in cancer-associated hypercoagulation stroke and often heralds occult malignancy.
Source: The Neurologist - March 1, 2022 Category: Neurology Tags: Original Articles Source Type: research
Impact of Body Mass Index on Obesity-Related Cancer and Cardiovascular Disease Mortality; The Japan Collaborative Cohort Study
CONCLUSION: A BMI ≥ 25 kg/m2 is associated with an increased risk of obesity-related cancer in women and CVD in both sexes.PMID:34880165 | DOI:10.5551/jat.63143
Source: Journal of Atherosclerosis and Thrombosis - December 9, 2021 Category: Cardiology Authors: Masaaki Matsunaga Hiroshi Yatsuya Hiroyasu Iso Yuanying Li Kazumasa Yamagishi Naohito Tanabe Yasuhiko Wada Atsuhiko Ota Koji Tamakoshi Akiko Tamakoshi JACC Study Group Source Type: research
