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Health economic evaluation of the 'Flying Intervention Team as a novel stroke care concept for rural areas: study protocol of the TEMPiS-GÖA study
The objective of the present paper is to describe the methods for the economic evaluation (TEMPiS-Gesundheitsökonomische Analyse (TEMPiS-GÖA)) alongside the TEMPiS-FIT study to determine whether the new form of care is cost-effective compared with standard care. Methods and analysis The within-trial cost-effectiveness analysis (CEA) and cost–utility analysis (CUA) will be performed from a statutory health insurance perspective as well as from a societal perspective over the time horizon of 12 months after the patients’ hospital discharge. Direct costs from outpatient and inpatient care are coll...
Source: BMJ Open - September 20, 2022 Category: General Medicine Authors: Coors, M., Flemming, R., Schüttig, W., Hubert, G. J., Hubert, N. D., Sundmacher, L. Tags: Open access, Health economics Source Type: research

City Heat is Worse if You ’re Not Rich or White. The World’s First Heat Officer Wants to Change That
Jane Gilbert knows she doesn’t get the worst of the sticky heat and humidity that stifles Miami each summer. She lives in Morningside, a coastal suburb of historically preserved art deco and Mediterranean-style single-family homes. Abundant trees shade the streets and a bay breeze cools residents when they leave their air conditioned cars and homes. “I live in a place of privilege and it’s a beautiful area,” says Gilbert, 58, over Zoom in early June, shortly after beginning her job as the world’s first chief heat officer, in Miami Dade county. “But you don’t have to go far to see t...
Source: TIME: Science - July 7, 2021 Category: Science Authors: Ciara Nugent Tags: Uncategorized climate change feature Londontime Source Type: news

Long-term cardiometabolic disease risk in women with PCOS: a systematic review and meta-analysis
AbstractBACKGROUNDPolycystic ovary syndrome (PCOS) is associated with cardiometabolic disease, but recent systematic reviews and meta-analyses of longitudinal studies that quantify these associations are lacking.OBJECTIVE AND RATIONALEIs PCOS a risk factor for cardiometabolic disease?SEARCH METHODSWe searched from inception to September 2019 in MEDLINE and EMBASE using controlled terms (e.g. MESH) and text words for PCOS and cardiometabolic outcomes, including cardiovascular disease (CVD), stroke, myocardial infarction, hypertension (HT), type 2 diabetes (T2D), metabolic syndrome and dyslipidaemia. Cohort studies and case ...
Source: Human Reproduction Update - September 30, 2020 Category: OBGYN Source Type: research

Challenge to the Intestinal Mucosa During Sepsis
Conclusion The impact of sepsis on the gut is manifold, e.g., sepsis mediated alteration of the gut-blood barrier and increase in the intestinal permeability, which may correlate with the phenomena of bacterial translocation and lymphatic activation (“toxic-lymph”). Systemic consequences of sepsis are widespread and concern to the coagulative system, the microbiome as well as enzymes, such as pancreatic proteases, MMPs and IAPs. Nevertheless, the therapeutic approaches for modulating the mucosal immune system are still rarely effective in daily routine. Recent published studies showing that treatment with ...
Source: Frontiers in Immunology - April 29, 2019 Category: Allergy & Immunology Source Type: research

Associations of Anemia With Outcomes in Patients With Spontaneous Intracerebral Hemorrhage: A Meta-Analysis
Conclusions: Anemia on admission was associated with higher mortality and an increased risk of poor outcome in patients with ICH. However, the results were limited by the high heterogeneity of included studies. Prospective, multi-center or population-based, large sample cohort studies are needed in the future. Introduction Intracerebral hemorrhage (ICH) is the second most common cause of stroke and a highly lethal disease (1), which still lacks effective therapeutic interventions (2, 3). Although age, baseline ICH volume and neurological status on admission are well-known predictors of outcome of ICH (4), none of t...
Source: Frontiers in Neurology - April 24, 2019 Category: Neurology Source Type: research

Robot-Assisted Therapy in Upper Extremity Hemiparesis: Overview of an Evidence-Based Approach
Conclusion Robotic therapy has matured and represents an embodiment of a paradigm shift in neurorehabilitation following a stroke: instead of focusing on compensation, it affords focus in ameliorating the impaired limb in line with concepts of neuroplasticity. This technology-based treatment provides intensity, interactivity, flexibility, and adaptiveness to patient's performance and needs. Furthermore, it increases the productivity of rehabilitation care. Of course, efficiency must be discussed within a local perspective. For example, following the cost containment shown in the VA ROBOTICS study (46), the UK Nati...
Source: Frontiers in Neurology - April 23, 2019 Category: Neurology Source Type: research

Corticospinal Tract Integrity and Long-Term Hand Function Prognosis in Patients With Stroke
Conclusions: The present study showed that CST integrity (at 6 months after onset) in patients with chronic stroke was related to functional hand status. In addition, the mid-pons FA value was more predictive of functional restoration of the hand than the FN or FA value at the pontomedullary junction. These results may be useful in predicting the functional restoration of the hand and understanding the functional prognosis of stroke. Introduction Restoration of hand function is one of the most important goals for patients with stroke (1). Thus, techniques that aid in predicting restoration of hand function are also i...
Source: Frontiers in Neurology - April 14, 2019 Category: Neurology Source Type: research

Dynamic Office Environments Improve Brain Activity and Attentional Performance Mediated by Increased Motor Activity
Conclusion The results of the present study reveal short- and mid-term effects on attentional and vigilance performance, and EEG brain activity when working in a dynamic versus a static environment. During working in a dynamic office, attentional and vigilance performance increased compared to working in a static office. Brain activities show increased alpha, beta and gamma power in the frontal and central areas in the attentional task with increased theta, alpha, and beta activity in the vigilance task. These findings suggest that working in a dynamic office environment stimulates the brain towards an optimum psychophysi...
Source: Frontiers in Human Neuroscience - April 11, 2019 Category: Neuroscience Source Type: research

Penumbra touts real-world study results in Penumbra System acute ischemic stroke trial
Penumbra (NYSE:PEN) today released results from the Promise real-world safety and efficacy study of its Penumbra System with ACE 68 and 64 reperfusion catheters as a treatment for patients with acute ischemic stroke, touting high rates of revascularization and low rates of all-cause mortality. Results were presented at the International Stroke Conference this week in Los Angeles. “We thank the Promise investigators for this important contribution to the growing body of global evidence supporting Adapt as a frontline approach for patients with acute ischemic stroke. The Promise study affirms our belief that the Penu...
Source: Mass Device - January 25, 2018 Category: Medical Devices Authors: Fink Densford Tags: Clinical Trials Vascular Penumbra Inc. Source Type: news

Endocrine Disruptors and Health Effects in Africa: A Call for Action
Conclusion: To address the many challenges posed by EDCs, we argue that Africans should take the lead in prioritization and evaluation of environmental hazards, including EDCs. We recommend the institution of education and training programs for chemical users, adoption of the precautionary principle, establishment of biomonitoring programs, and funding of community-based epidemiology and wildlife research programs led and funded by African institutes and private companies. https://doi.org/10.1289/EHP1774 Received: 16 February 2017 Revised: 22 May 2017 Accepted: 24 May 2017 Published: 22 August 2017 Address correspond...
Source: EHP Research - August 23, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Commentary Source Type: research

European Stroke Conference. 26th Conference, Berlin, Germany, May 24-26, 2017: Abstract e-Book
Cerebrovasc Dis 2017;43(suppl 1):I-II
Source: Cerebrovascular Diseases - July 6, 2017 Category: Neurology Source Type: research