Endocrine Disruptors and Health Effects in Africa: A Call for Action
Conclusion: To address the many challenges posed by EDCs, we argue that Africans should take the lead in prioritization and evaluation of environmental hazards, including EDCs. We recommend the institution of education and training programs for chemical users, adoption of the precautionary principle, establishment of biomonitoring programs, and funding of community-based epidemiology and wildlife research programs led and funded by African institutes and private companies. https://doi.org/10.1289/EHP1774 Received: 16 February 2017 Revised: 22 May 2017 Accepted: 24 May 2017 Published: 22 August 2017 Address correspondence to M. Bornman, Dean’s Office and School of Health Systems and Public Health, Faculty of Health Sciences, Health Sciences Building, Room 4.14, Bophelo Rd., Gezina, Private Bag X323, Pretoria 0001, South Africa. Telephone: 012 319 2206. Email: Riana.Bornman@up.ac.za None of the authors is employed or was funded by any of the companies sponsoring the Endocrine Disrupting Chemicals (EDCs) in Africa meeting from which this commentary draws information and opinion. B.B. receives royalties from various patents related to PPARgamma, SXR, and BXR. J.D. is employed by the International Persistent Organic Pollutants (POPs) Elimination Network (IPEN), a network of public interest nongovernmental organizations working in more than 100 countries to reduce and eliminate the harm to human health and the environment from toxic chemicals. J.D. receives no personal ...
This study investigates the distribution of femoral metastases in cancer patients, specifically addressing the incidence of distal femoral metastases. PET/CT examinations routinely extend only to mid-thigh level, precluding detection of distal metastases. We found a total of 208 femoral metastases in 112 patients. 30% had distal femoral metastases in addition to other areas of involvement. 7% of patients with femoral metastases had only distal femur disease. 6 patients had distal pathologic fractures. Exclusion of the distal femur during PET/CT may result in a missed or delayed diagnosis that could contribute to the develo...
In conclusion, implementation of FLS was associated with a reduced risk of recurrent fracture, indicating that FLSs should be included routinely at hospitals treating fracture patients.This article is protected by copyright. All rights reserved.
Authors: Xu H, Dong L, Bin Z, Yansong H, Shaofeng L, Chang L, Chen C, Changli W Abstract Despite the excellent efficacy and low toxicity of photoresponse therapy, which has attracted considerable attention for use in non-small cell lung cancer (NSCLC) therapy, unsatisfactory cellular permeability, and instability, both in vitro and in vivo have limited further clinical applications of indole cyanine photosensitizers. Here, we explore the supramolecular self-assembly of a 'hyalurosome' that is mediated by calcium phosphate nanonuclei. Through hyaluronate-mediated CD44 targeting, the constructed hyalurosome...
To compare the outcomes of laparoscopic retroperitoneal hysterectomy (LRH) in morbidly obese patients (BMI ≥ 40 k/m2) versus non-obese patients (BMI
To assess factors and charges associated with hospital revisits following benign hysterectomy in the United States.
To compare the outcomes of laparoscopic-assisted myomectomy (LAM) in morbidly obese patients (BMI ≥ 40 k/m2) versus non-obese patients (BMI
To identify the independent risk factors of concurrent endometrial cancer among women with endometrial hyperplasia and build the clinical prediction model incorporating the clinical and pathological markers.
Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are a rare single spectrum of severe epidermolytic reactions that can involve the vulva, vagina, and cervix. Description of specific management techniques for vulvovaginal SJS/TEN in the literature is sparse. This is a retrospective review of women treated at a tertiary care burn center for SJS/TEN with vulvovaginal involvement.
To assess the effects of site and route of morcellation on perioperative outcomes in patients with body mass index (BMI) ≥40 (WHO class 3 obesity).
Endometriosis is a prevalent disease associated with significant cost; over $49 billion in medical costs is spent annually in the United States (US) alone. Limited data exist on the cost-effectiveness of various clinical regimens to guide management. We sought to determine which sequence of therapies would be most cost-effective for the treatment of endometriosis-related pain.
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