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Drug: Carbamazepine
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Total 179 results found since Jan 2013.
Increased risk of stroke and myocardial infarction in patients with epilepsy: A systematic review of population-based cohort studies.
CONCLUSIONS: Patients with epilepsy are at higher risk of subsequent stroke and MI in comparison with subjects without epilepsy. Although individual AEDs may carry different risks of cardio- and cerebrovascular disease, the clinical relevance of the metabolic effects of the enzyme-inducing AEDs is still uncertain. This article is part of the Special Issue "Seizures & Stroke.
PMID: 31182394 [PubMed - as supplied by publisher]
Source: Epilepsy and Behaviour - June 6, 2019 Category: Neurology Authors: Brigo F, Lochner P, Nardone R, Manganotti P, Lattanzi S Tags: Epilepsy Behav Source Type: research
Mood stabilisers and risk of stroke in bipolar disorder.
CONCLUSIONS: Use of carbamazepine and valproic acid, but not lithium and lamotrigine, is associated with increased risk of stroke in patients with bipolar disorder.Declaration of interestNone.
PMID: 30295208 [PubMed - as supplied by publisher]
Source: The British Journal of Psychiatry for Mental Science - October 10, 2018 Category: Psychiatry Tags: Br J Psychiatry Source Type: research
Increased risk of stroke and myocardial infarction in patients with epilepsy: A systematic review of population-based cohort studies
ConclusionsPatients with epilepsy are at higher risk of subsequent stroke and MI in comparison with subjects without epilepsy. Although individual AEDs may carry different risks of cardio- and cerebrovascular disease, the clinical relevance of the metabolic effects of the enzyme-inducing AEDs is still uncertain.This article is part of the Special Issue “Seizures & Stroke
Source: Epilepsy and Behavior - June 8, 2019 Category: Neurology Source Type: research
Efficacy of phenytoin, valproic acid, carbamazepine and new antiepileptic drugs on control of late‐onset post‐stroke epilepsy in Taiwan
ConclusionsThis large nationwide, population‐based study demonstrated that late‐onset post‐stroke epilepsy patients using VPA and new AEDs have better seizure control than those using PHT as demonstrated by lower risks of ER visits and hospitalization.
Source: European Journal of Neurology - July 1, 2015 Category: Neurology Authors: Y.‐H. Huang, N.‐F. Chi, Y.‐C. Kuan, L. Chan, C.‐J. Hu, H.‐Y. Chiou, L.‐N. Chien Tags: Original Article Source Type: research
Levetiracetam administration is correlated with lower mortality in patients with mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes: a retrospective study.
CONCLUSIONS: The LEV administration is associated with lower mortality in patients with MELAS in this retrospective study. Further laboratory research and prospective cohort studies are needed to confirm whether LEV has neuroprotective effects on patients with mitochondrial diseases.
PMID: 30681492 [PubMed - in process]
Source: Chinese Medical Journal - January 27, 2019 Category: General Medicine Authors: Zhang Z, Zhao DH, Zhao XT, Zhang X, Xiong H, Bao XH, Yuan Y, Wang ZX Tags: Chin Med J (Engl) Source Type: research
Randomized Controlled Trials of Antiepileptic Drugs for the Treatment of Post-stroke Seizures: a Systematic Review with Network Meta-analysis
ConclusionsDirect and indirect comparisons did not find a difference in seizure freedom between the various AEDs, probably because of the small number of patients included. LEV and LTG appears better tolerated than CR-CBZ and LEV seems associated with more AEs than LTG. Further studies are required to provide robust evidence on efficacy and tolerability of AEDs for treating poststroke epilepsy.
Source: Seizure - August 4, 2018 Category: Neurology Source Type: research
Oxcarbazepine versus Carbamazepine for the Treatment of Post-Stroke Epilepsy: A Systematic Review and Meta-Analysis
Conclusions OXC seems to be superior to CBZ in the treatment of PSE with being more effective and safer. However, more research on OXC and CBZ in the treatment of PSE is needed in the later stage due to the limitation of sample size and number of patients in this study.PMID:34936076 | DOI:10.5137/1019-5149.JTN.34664-21.3
Source: Turkish Neurosurgery - December 22, 2021 Category: Neurosurgery Authors: Ying-Ju Zhang Xue-Ming Lu Pei-Wu Li Chang-An Guo Dong-Jun Wan Source Type: research
Stroke and Ischemic Heart Disease With Enzyme-inducing Antiseizure Medications: Time to Change Prescribing Habits
Conclusions and Relevance: The hazard of incident cardiovascular disease is higher in those receiving eiASMs. The association is dose dependent and the absolute difference in hazard seems to reach clinical significance by approximately 10 years from first exposure.PMID:35444497 | PMC:PMC8988723 | DOI:10.1177/15357597211070392
Source: Epilepsy Curr - April 21, 2022 Category: Neurology Authors: David G Vossler Source Type: research
