Discussing the risks related to epilepsy—An holistic approach
Publication date: Available online 20 February 2020Source: SeizureAuthor(s): Roy G. Beran (Source: Seizure)
Source: Seizure - February 21, 2020 Category: Neurology Source Type: research

Prone, lateral, or supine positioning at seizure onset determines the postictal body position: A multicenter video-EEG monitoring cohort study
Publication date: Available online 21 February 2020Source: SeizureAuthor(s): Katharina Mahr, Marc-Philipp Bergmann, Lara Kay, Leona Möller, Philipp S. Reif, Laurent M. Willems, Katja Menzler, Susanne Schubert-Bast, Karl Martin Klein, Susanne Knake, Felix Rosenow, Johann Philipp Zöllner, Adam StrzelczykABSTRACTPurposeMost patients who die from sudden unexpected death in epilepsy (SUDEP) are found in the prone position. We evaluated whether changes in body position occur during generalized convulsive seizures (GCSs).MethodGCSs in patients undergoing video-EEG-monitoring between 2007 and 2017 at epilepsy centers in ...
Source: Seizure - February 21, 2020 Category: Neurology Source Type: research

Lacosamide in the general population and in people with intellectual disability: Similar responses?
ConclusionThere were no differences for LCM outcomes between general and ID groups. Slower LCM titration in ID populations in the first 3 months was associated with higher retention and lower behavioural side effects as compared to similar European studies. (Source: Seizure)
Source: Seizure - February 20, 2020 Category: Neurology Source Type: research

Clinically unnecessary and avoidable emergency health service use for epilepsy: A survey of what English services are doing to reduce it
ConclusionReducing emergency hospital use by PWE is a high priority for most health services in England and a number of new services have been developed. However, they have not been consistently implemented and innovation is lacking in some areas of care. (Source: Seizure)
Source: Seizure - February 19, 2020 Category: Neurology Source Type: research

Stereo-EEG exploration in the insula/operculum in paediatric patients with refractory epilepsy
ConclusionsOur data suggest an important role of the I/O region with frequent onset or propagation to the I/O region (at least 64% of all 53 sEEG cases). Semiology appears less specific than in adults. Insula depth electrode insertion is safe with subsequent good surgical outcomes albeit common transient deficits. (Source: Seizure)
Source: Seizure - February 15, 2020 Category: Neurology Source Type: research

The abbreviation “PWE” may carry a negative connotation compared with the labels “person with epilepsy” and “epileptic”
This study analyzed college students position changes, influenced by three different labels of PWE.MethodsObservational, descriptive, cross-sectional study. Students of three schools answered one of three questionnaires whose content changed in the labeling form: person with epilepsy, epileptic or PWE. Proportions were compared with Chi square test or Fisher's exact test to explore considering age, gender, religion practicing, socioeconomic status, knowing an affected person and by faculty.ResultsA total of 273 questionnaires were included were distributed in medicine 133 (48.7%), engineering 108 (39.6%) and law 32 (11.7%)...
Source: Seizure - February 15, 2020 Category: Neurology Source Type: research

Maladaptive emotional regulation in patients diagnosed with psychogenic non-epileptic seizures (PNES) compared with healthy volunteers
Publication date: Available online 13 February 2020Source: SeizureAuthor(s): Lenka Krámská, Lucia Hrešková, Zdeněk Vojtěch, David Krámský, Lorna MyersAbstractPurposeThe term PNES refers to a conversion disorder that mimics epileptic seizures but has a psychological etiology. Recent studies report that in patients with PNES, there is reduced understanding of emotions, impulse control difficulties, and limited access to emotional regulation strategies. The aim of this study was to compare patients diagnosed with PNES with healthy volunteers on the presence of maladaptive emotional ...
Source: Seizure - February 15, 2020 Category: Neurology Source Type: research

Editorial Board
Publication date: February 2020Source: Seizure, Volume 75Author(s): (Source: Seizure)
Source: Seizure - February 14, 2020 Category: Neurology Source Type: research

Determining the quality of life of children living with epilepsy in Kenya—A cross-sectional study using the CHEQOL-25 tool
ConclusionThis study demonstrated that a good quality of life was reported by the majority of CWE and their caregivers, although some factors such as a male caregiver gender and lower level of education were associated with poor QoL. (Source: Seizure)
Source: Seizure - February 12, 2020 Category: Neurology Source Type: research

Perampanel effect on sleep architecture in patients with epilepsy
ConclusionPerampanel improved sleep architecture in patients with focal refractory epilepsy without worsening daytime sleepiness. (Source: Seizure)
Source: Seizure - February 11, 2020 Category: Neurology Source Type: research

Managing the Patient with Epilepsy and Renal Impairment
ConclusionThe disposition of AEDs can be altered in patients with impaired renal function, leading to a higher risk of AED toxicity or therapy failure. Renal dosage adjustment and close monitoring is recommended. Although AED-induced nephrotoxicity is rare, it is unpredictable and clinicians need to vigilant about this possibility. In addition, AEDs renal adverse reactions and renal drug interactions should be considered when selecting an AED. (Source: Seizure)
Source: Seizure - February 11, 2020 Category: Neurology Source Type: research

Preoperative language mapping using navigated TMS compared with extra-operative direct cortical stimulation using intracranial electrodes: A case report
Publication date: March 2020Source: Seizure, Volume 76Author(s): Fahmida A. Chowdhury, Lorenzo Caciagli, Benjamin P. Whatley, Charlotte McLaughlin, Brett Sanders, Tim Wehner, Beate Diehl (Source: Seizure)
Source: Seizure - February 9, 2020 Category: Neurology Source Type: research

Epilepsy in immigrants and Swedish-born: a cohort study of all adults 18 years of age and older in Sweden
ConclusionsRisk of epilepsy was lower in immigrants in general compared to the Swedish-born population; but with higher incidence in some specific groups. (Source: Seizure)
Source: Seizure - February 9, 2020 Category: Neurology Source Type: research

Understanding the value of meta-analysis in Epilepsy. Are we using more than required?
Publication date: Available online 7 February 2020Source: SeizureAuthor(s): Jose F. Tellez-Zenteno, Lizbeth Hernandez-Ronquillo, Alyssa Denton (Source: Seizure)
Source: Seizure - February 9, 2020 Category: Neurology Source Type: research

Micturition reflex epilepsy with tonic seizures – A rare semiology with insights from magnetoencephalography
Publication date: Available online 8 February 2020Source: SeizureAuthor(s): Lakshminarayanapuram Gopal Viswanathan, K Bhargava Gautham, Ajay Asranna, Ravindranadh Mundlamuri Chowdary, Aparajita Chatterjee, Raghavendra Kenchaiah, Jitender Saini, Rose Dawn Bharath, Karthik Kulanthaivelu, Sandhya Mangalore, Chandana Nagaraj, Sanjib Sinha (Source: Seizure)
Source: Seizure - February 9, 2020 Category: Neurology Source Type: research

Risks of seizure with fatal traffic crash at wheel in people with epilepsy
ConclusionThe risk of fatal traffic crashes in people with epilepsy for 1-year and 2-year seizure-free periods was estimated to be lower than that of some age groups in the general population. The increased risk in 1-year seizure freedom from that in 2-year seizure freedom was relatively small. (Source: Seizure)
Source: Seizure - February 8, 2020 Category: Neurology Source Type: research

Is rat hippocampus section immunostaining an indicator for immunotherapy in cryptogenic adult new-onset refractory status epilepticus (NORSE)?
ConclusionsThe immunostaining on serum and/or CSF from NORSE patients did not indicate the progression to SRSE and clinical outcomes. (Source: Seizure)
Source: Seizure - February 5, 2020 Category: Neurology Source Type: research

Predicting outcome of epilepsy surgery in clinical practice: prediction models vs. clinical acumen
ConclusionsPreoperative outcome estimates corresponded well with observed outcome indicating adequate patient counseling. (Source: Seizure)
Source: Seizure - February 2, 2020 Category: Neurology Source Type: research

Very late-onset mitochondrial cytopathy featuring epilepsia partialis continua and bilateral deafness; a case report
Publication date: Available online 28 January 2020Source: SeizureAuthor(s): Michael CH Li, Mkael Symmonds, Pieter M Pretorius, Fintan Sheerin, Kannan Nithi, Monika Hofer, Joanna Poulton, Arjune Sen (Source: Seizure)
Source: Seizure - January 30, 2020 Category: Neurology Source Type: research

Surgical disconnection of epilepsy network correlates with improved outcomes
Publication date: Available online 29 January 2020Source: SeizureAuthor(s): Elliot G. Neal, Stephanie Maciver, Mike R. Schoenberg, Fernando L. ValeAbstractPurposeA novel software algorithm combining non-invasive EEG and resting state functional MRI data to map networks of cortex correlated to epileptogenic tissue was used to map an epilepsy network non-invasively. The relationship between epilepsy network connectivity and outcomes after surgery was investigated using this non-invasive and non-concurrent modeling algorithm.MethodScalp EEG and resting state functional MRI were acquired for nineteen patients with temporal lob...
Source: Seizure - January 30, 2020 Category: Neurology Source Type: research

Epilepsy in paediatric patients with Parry-Romberg Syndrome: a review of the literature
ConclusionTo the best of our knowledge, this is the first review dedicated to the characteristics of paediatric patients with PRS and epilepsy. Seizures are usually focal, became refractory in 40%, and have a significant impact on the quality of life and neurodevelopment of patients. (Source: Seizure)
Source: Seizure - January 28, 2020 Category: Neurology Source Type: research

Hippocampal microstructural architecture and surgical outcome: Hippocampal diffusivity could predict seizure relapse
Publication date: Available online 26 January 2020Source: SeizureAuthor(s): Jacint Sala-Padro, Júlia Miró, Antoni Rodriguez-Fornells, Manolo Quintana, Noemi Vidal, Gerard Plans, Mila Santurino, Mercè Falip, Estela CàmaraAbstractPurposeOur aim was to study the microstructural architecture of the contralateral hippocampus to the affected side in patients with temporal lobe epilepsy with hippocampal sclerosis (TLE-HS) and its relation with surgical outcome.MethodWe included 33 consecutive patients evaluated in our epilepsy surgery program during a five-year period. They underwent a presurgical MRI ...
Source: Seizure - January 27, 2020 Category: Neurology Source Type: research

Children with allergic rhinitis and a risk of epilepsy: A nationwide cohort study
Publication date: Available online 24 January 2020Source: SeizureAuthor(s): Hui-Hsien Pan, Tung-Wei Hung, Jeng-Dau Tsai, Hsuan-Ju Chen, Pei-Fen Liao, Ji-Nan SheuABSTRACTPurposeLittle is known about whether allergic disease is associated with a subsequent increased risk of childhood-onset epilepsy. We used a large, population-based cohort study to examine whether children with antecedent allergic rhinitis (AR) were associated with a subsequent increased risk of epilepsy.MethodsThis retrospective population-based cohort study was conducted by using data from the 2000–2012 Taiwan’s National Health Insurance Resear...
Source: Seizure - January 25, 2020 Category: Neurology Source Type: research

Automatic assessment of the myoclonus severity from videos recorded according to standardized Unified Myoclonus Rating Scale protocol and using human pose and body movement analysis
ConclusionAutomatic quantification of myoclonic jerks using human pose and body movement analysis of patients’ videos is feasible and was found to be quite consistent with the accepted clinical gold standard quantification method. Based on the results of this study, the automatic analytical method should be further developed and validated to improve myoclonus severity follow-up for EPM1 patients. (Source: Seizure)
Source: Seizure - January 25, 2020 Category: Neurology Source Type: research

Exploring epilepsy attendance at the emergency department and interventions which may reduce unnecessary attendances: a scoping review
ConclusionThe findings indicate varied reasons for attendance at ED following seizure, including mental health and knowledge of seizure management and lack of education. Implementations of care pathways in ED have been found to reduce admission related costs. (Source: Seizure)
Source: Seizure - January 25, 2020 Category: Neurology Source Type: research

Plasma-lactate levels in simulated seizures – an observational study
ConclusionOur data indicate that high rises in lactate levels after seizures is not specific for an epileptic origin. Further study of lactate as marker for epileptic seizures is warrented. (Source: Seizure)
Source: Seizure - January 24, 2020 Category: Neurology Source Type: research

Somatostatin receptor expression and mTOR pathway activation in glioneuronal tumours of childhood
ConclusionsExpression of SSTRs and activation of mTOR pathway in paediatric glioneuronal tumour suggest that somatostatin analogues and mTOR inhibitors may have potential therapeutic implications in a subset of inoperable childhood glioneuronal tumours causing medically refractory epilepsy and/or tumour growth. Further clinical studies are warranted to validate these findings. (Source: Seizure)
Source: Seizure - January 22, 2020 Category: Neurology Source Type: research

Long-term follow-up of post-stroke epilepsy after ischemic stroke: room for improved epilepsy treatment
Publication date: Available online 21 January 2020Source: SeizureAuthor(s): Petra Redfors, Lukas Holmegaard, Annie Pedersen, Christina Jern, Kristina MalmgrenAbstractPurposeTo assess long-term incidence and predictors of post-stroke epilepsy (PSE) and to evaluate the antiepileptic drug (AED) treatment in a well characterized cohort of middle-aged patients.MethodsThe study is based on the Sahlgrenska Study on Ischemic stroke, and included 1066 adult patients with first-ever or recurrent acute ischemic stroke (AIS) before the age of 70. Early seizures (ES) were defined as seizures within one week and PSE as unprovoked seizur...
Source: Seizure - January 22, 2020 Category: Neurology Source Type: research

Determining the quality of life of children living with epilepsy in kenya - a cross-sectional study using the cheqol-25 tool
ConclusionThis study demonstrated that a good quality of life was observed among the majority of CWE and their caregivers, although some factors such as a male caregiver gender and lower level of education were associated with poor QoL. (Source: Seizure)
Source: Seizure - January 22, 2020 Category: Neurology Source Type: research

Intrinsic hippocampal and thalamic networks in temporal lobe epilepsy with hippocampal sclerosis according to drug response
ConclusionWe found that the intrinsic hippocampal network in patients with TLE with HS was different according to AED response. The patients with DRE had more severe disruptions of the intrinsic hippocampal network than those with DCE compared with healthy controls. These findings suggested that the hippocampal network might be related to AED response and could be a new biomarker of medical outcome in patients with TLE with HS. (Source: Seizure)
Source: Seizure - January 21, 2020 Category: Neurology Source Type: research

Valproic acid prescription trends among females of childbearing age in Estonia: A 14-year nationwide prescription database study
This study aimed to determine the prevalence of VPA use in 2005–2018 in Estonia, with special attention to females of childbearing age.MethodsIn this retrospective nationwide population-based cohort study, outpatient prescription data from the national health insurance provider were used. Annual sex- and age-specific prevalence rates were calculated, and changes therein during the study period were evaluated.ResultsThe annual rates of VPA use among females of childbearing age increased significantly in 2005–2014. After 2014, the increasing trend stopped; in 2014–2018, the prevalence rates declined slightl...
Source: Seizure - January 12, 2020 Category: Neurology Source Type: research

Posterior reversible encephalopathy syndrome in preeclampsia and eclampsia: The role of hypomagnesemia
Publication date: Available online 7 January 2020Source: SeizureAuthor(s): Xiaobo Fang, Haibin Wang, Zifan Liu, Jia Chen, Hu Tan, Yanling Liang, Dunjin ChenAbstractPurposePosterior reversible encephalopathy syndrome (PRES), defined by its clinical and imaging manifestations, is a critical maternal complication. The specific pathophysiological mechanism of PRES has not been fully elucidated and remains controversial. Recently, several case studies reported that hypomagnesemia is present in the acute phase of PRES regardless of its etiology. Moreover, magnesium sulfate is a conventional treatment for preeclampsia (PE) and ec...
Source: Seizure - January 9, 2020 Category: Neurology Source Type: research

Neurocysticercosis in People with Epilepsy in Sub-Saharan Africa: A Systematic Review and Meta-analysis of the Prevalence and Strength of Association
Publication date: Available online 7 January 2020Source: SeizureAuthor(s): Lukman Femi Owolabi, Bappa Adamu, Abubakar Muhammed Jibo, Shakirah Desola Owolabi, Adamu Isa Imam, Ibrahim Daiyyabu AlhajiAbstractPurposeWe analyzed studies on neurocysticercosis (NCC) and epilepsy across Sub-Saharan Africa (SSA) to determine the prevalence of NCC in people with epilepsy (PWE) and the strength of association of NCC with epilepsy in the region.MethodsWe conducted a systematic review of the existing literature on NCC and epilepsy in SSA. Diagnostic methods for NCC in the studies selected for our analysis included one or more of the fo...
Source: Seizure - January 9, 2020 Category: Neurology Source Type: research

Evaluation of Olfactory and Gustatory Changes in Patients with Mesial Temporal Lobe Epilepsy
ConclusionsOlfactory function was significantly impaired in patients with MTLE compared with healthy controls in all domains, namely threshold, discrimination, and identification. In addition, olfactory bulbus volume was smaller in patients with olfactory dysfunction. (Source: Seizure)
Source: Seizure - January 7, 2020 Category: Neurology Source Type: research

Levetiracetam and cutaneous adverse reactions: a systematic review of descriptive studies
ConclusionClinicians should be aware of the possible CADRs induced by LEV to avoid fatal condition. Immediate withdrawal of the drug and supporting care seem to be effective in the management of the CADRs.Registration Number: International Prospective Register for Systematic Reviews (PROSPERO) number CRD42019141002. (Source: Seizure)
Source: Seizure - January 4, 2020 Category: Neurology Source Type: research

Outcome of status epilepticus and the predictive value of the EMSE and STESS scores: a prospective study
ConclusionsOver 40% of SE patients suffer adverse outcomes. The EMSE-EAC and STESS are useful in short-term mortality prediction, with a high negative predictive value. The optimized cutoff points for the EMSE-EAC and STESS were ≥ 34 and ≥ 4 for cohort, respectively. (Source: Seizure)
Source: Seizure - January 4, 2020 Category: Neurology Source Type: research

The Exploration of the Spectrum of Motor Manifestations of Anti-LGI1 Encephalitis beyond FBDS
Conclusions1. Atypical seizures, for instance, seizures without EEG evolution, are not rare but likely to be overlooked. 2. FBDS is closely linked with epileptic seizures, revealing FBDS to be a part of epileptic attacks. 3. HMs could expand the spectrum of motor manifestations, overlapping with sleep disorders. 4. The high prevalence of these motor events might be due to the disrupted cortical-subcortical network, which is critical in motor control and sleep. (Source: Seizure)
Source: Seizure - January 3, 2020 Category: Neurology Source Type: research

Intubation for Psychogenic Non-Epileptic Attacks: Frequency, Risk Factors, and Impact on Outcome
Publication date: Available online 31 December 2019Source: SeizureAuthor(s): Tanuwong Viarasilpa, Nicha Panyavachiraporn, Gamaleldin Osman, Noel O. Akioyamen, Vibhangini S. Wasade, Gregory Barkley, Stephan A. MayerAbstractPurposePatients with psychogenic non-epileptic attacks (PNEA) sometimes receive aggressive treatment leading to endotracheal intubation. We sought to identify the frequency, risk factors, and impact on outcome of intubation for PNEA.MethodsWe retrospectively reviewed all PNEA patients admitted via the emergency department (ED) who had an episode of PNEA documented by continuous video electroencephalograph...
Source: Seizure - January 1, 2020 Category: Neurology Source Type: research

Drug withdrawal in the Epilepsy monitoring unit – The Patsalos Table
Publication date: Available online 28 December 2019Source: SeizureAuthor(s): Jack Kirby, Veronica M Leach, Alice Brockington, Phillip Patsalos, Markus Reuber, John Paul LeachAbstractInvestigation of possible candidates for epilepsy surgery will usually require inpatient EEG to capture seizures and allow full operative planning. Withdrawal of antiepileptic drugs increases the yield of this valuable diagnostic information and the benefits of this should justify any increase in the risk of harm associated with these seizuresThis paper outlines our opinion on what would constitute proposed best practice for management of antie...
Source: Seizure - December 30, 2019 Category: Neurology Source Type: research

Safety, tolerability and effectiveness of transition to eslicarbazepine acetate from carbamazepine or oxcarbazepine in clinical practice
ConclusionESL was efficacious and generally well tolerated in patients transitioning from carbamazepine or oxcarbazepine in clinical practice due to inadequate seizure control or intolerable AEs with these agents. (Source: Seizure)
Source: Seizure - December 24, 2019 Category: Neurology Source Type: research

The efficacy of perampanel in young children with drug-resistant epilepsy
ConclusionsAs a real-world pediatric case series, our study demonstrated the efficacy and tolerability of perampanel in young children with intractable epilepsy. In our experience, lower starting and maintenance dose of perampanel would be effective in the pediatric group. We also propose the use of perampanel as an effective therapy for epilepsy in children with TSC and Dravet syndrome. (Source: Seizure)
Source: Seizure - December 24, 2019 Category: Neurology Source Type: research

Change in the strategy for prophylactic diazepam use for febrile seizures and the impact on seizure recurrence within 24 hours
Publication date: Available online 23 December 2019Source: SeizureAuthor(s): Masataka Inoue, Shunichi Adachi, Isao Kawakami, Hiroshi KogaAbstractPurposeTo investigate the association between reduced prophylactic diazepam usage and short-term recurrence of febrile seizures (FSs) after the FS practice guideline was updated in Japan.MethodIn this single-center, retrospective study, children (6-60 months of age) with FS who were transported to our center by ambulance from January 2011 through December 2018 were included. Rectal administration of diazepam (0.3-0.5 mg/kg) after the first seizure and seizure recurrence wit...
Source: Seizure - December 24, 2019 Category: Neurology Source Type: research

Epilepsy and autoimmune diseases: comorbidity in a national patient cohort
ConclusionsBased on a large, unselected patient cohort we find that epilepsy patients more often are prescribed medications used to treat type 1 diabetes mellitus, hypothyroidism, myasthenia gravis and MS. This was true for both men and women, and in most age-groups. (Source: Seizure)
Source: Seizure - December 24, 2019 Category: Neurology Source Type: research

Deep Brain Thalamic Stimulation in the Simultaneous Treatment of Generalised Epilepsy and Dystonic Tremord
Publication date: Available online 24 December 2019Source: SeizureAuthor(s): K.T. Elhadd, S.H. Alusi, U.C. Wieshmann, B. Hammersley, P.R. Eldridge (Source: Seizure)
Source: Seizure - December 24, 2019 Category: Neurology Source Type: research

Focal EEG abnormalities and focal ictal semiology in generalized epilepsy
Publication date: Available online 20 December 2019Source: SeizureAuthor(s): G. Fernandez-Baca Vaca, Jun T. ParkAbstractIn clinical practice, the diagnosis of focal vs generalized epilepsy dictates the management of the patient. The distinction between generalized and focal epilepsy is at times imperfect and some epilepsies have features that fall in between these two extremes. An example is the occurrence of focal interictal and focal ictal abnormalities in generalized epilepsies. As a part of the special issue on “The epileptogenic zone in pediatric epilepsy surgery”, this focused narrative review will discus...
Source: Seizure - December 21, 2019 Category: Neurology Source Type: research

The epileptogenic zone in pediatric epilepsy surgery: Special Issue
Publication date: Available online 19 December 2019Source: SeizureAuthor(s): Jun T. Park (Source: Seizure)
Source: Seizure - December 20, 2019 Category: Neurology Source Type: research

Anti-N-methyl-D-aspartate receptor encephalitis with accompanying ovarian teratoma in female patients from East China: Clinical features, treatment, and prognostic outcomes
ConclusionsSymptomatology and auxiliary findings indicate that ovarian teratoma may be the immunologic trigger for anti-NMDAR encephalitis patients, while viral infection is likely to play a major part in pathogenesis for those without any detectable tumor. Overall, anti-NMDAR encephalitis patients with teratomas present with milder neurological symptoms and have better long-term outcomes after tumor removal. (Source: Seizure)
Source: Seizure - December 19, 2019 Category: Neurology Source Type: research

Reduced Left Amygdala Volume in Patients with Dissociative Seizures (Psychogenic Nonepileptic Seizures)
This study specifically investigated differences of amygdalar and hippocampal volumes between patients with dissociative seizures (DS), mesial temporal lobe sclerosis (MTS), and normal controls (NC).MethodsBetween 2003 and 2018, 127 patients diagnosed with DS and 278 with MTS were recruited. An additional 52 NC subjects were recruited between 2015 and 2018. We retrospectively selected 29 patients with DS (male:female, 6:23) with absence of structural confounding factors and obtained sex- and age-matched MTS and NC. We used Neuroreader to assess the volume of the amygdala and hippocampus as a percentage of total intracrania...
Source: Seizure - December 19, 2019 Category: Neurology Source Type: research

Incidence of Early-Onset Epilepsy: A Prospective Population-based Study
Publication date: Available online 19 December 2019Source: SeizureAuthor(s): Matthew B. Hunter, Michael Yoong, Ruth E. Sumpter, Kirsten Verity, Jay Shetty, Ailsa McLellan, Richard F.M. ChinAbstractPurposeThe first five years of life reflect a critical period of development prior to formal education yet few epidemiological studies focus on children with early-onset epilepsy (CWEOE; onset
Source: Seizure - December 19, 2019 Category: Neurology Source Type: research

Psychogenic nonepileptic seizures: the sex ratio trajectory across the lifespan
Publication date: Available online 19 December 2019Source: SeizureAuthor(s): Ali A. Asadi-Pooya, Maryam HomayounAbstractPurposeWe investigated the sex ratio trajectory across the lifespan in patients with psychogenic nonepileptic seizures (PNES). We hypothesized that there are significant changes in the trajectory of the sex ratio in these patients across the lifespan with respect to the age at onset.MethodsIn this retrospective study, all patients with PNES, who were diagnosed at Shiraz Comprehensive Epilepsy Center, Iran, from 2008 until 2019, were investigated. We arbitrarily categorized the patients into five groups ac...
Source: Seizure - December 19, 2019 Category: Neurology Source Type: research