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Drug: Nitroglycerin

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Total 46 results found since Jan 2013.

Ambulance nitroglycerin patch to lower blood pressure did not improve stroke outcomes
(American Heart Association) Despite the promise of earlier small studies, a patch to lower stroke patient's blood pressure before reaching the hospital didn't improve stroke outcomes.
Source: EurekAlert! - Medicine and Health - February 6, 2019 Category: International Medicine & Public Health Source Type: news

Not Just Acid Reflux: The Need to Think Worst First
Discussion Heart disease is the leading cause of death in the United States.1 This year, 720,000 Americans will have a new coronary event—defined as first hospitalized myocardial infarction (MI) or coronary heart disease death—and around 335,000 will have a recurrent event. Approximately 35% of people who experience a coronary event in a given year and around 14% of patients who have an acute coronary syndrome will die from it.1 Roughly 60% of patients with an acute coronary syndrome are transported to the emergency department via ambulance.2–4. Up to one-third of patients experiencing an MI may not complain of chest...
Source: JEMS Special Topics - January 13, 2019 Category: Emergency Medicine Authors: Stephen Sanko, MD, FACEP Tags: Exclusive Articles Cardiac & Resuscitation Source Type: news

A multicenter trial of extracorporeal cardiac shock wave therapy for refractory angina pectoris: report of the highly advanced medical treatment in Japan
In this study, we further addressed the efficacy and safety of CSWT in a single-arm multicenter study approved as a highly advanced medical treatment by the Japanese Ministry of Health, Labour and Welfare. Fifty patients with refractory AP [mean age 70.9  ± 12.6 (SD) years, M/F 38/12] without the indications of percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG) were enrolled in 4 institutes in Japan. Ischemic myocardial regions in the left ventricle (LV) were identified by drug-induced stress myocardial perfusion imaging (MPI). Shock waves (200 shots/spot at 0.09 mJ/mm2) were applied t...
Source: Heart and Vessels - June 25, 2018 Category: Cardiology Source Type: research

Collateral Blood Flow Availability in Acute Ischemic Stroke: A Case Report (P4.360)
Conclusion: This case supports earlier autopsy specimen dissections indicating most borderzone collaterals linking to adjacent vascular territories are too small to generate the immediate flow needed to spare tissue proximal to a middle cerebral stem occlusion. Assuming acute vasodilation is possible for these vessels, the acute use of vasodilators such as nitroglycerin or hydralazine and calcium-channel blockers like Nimodipine could provide an area for future study.Disclosure: Dr. Rostanski has nothing to disclose. Dr. Lavine has nothing to disclose. Dr. Mohr has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Rostanski, S., Lavine, S., Mohr, J. Tags: Cerebrovascular Case Reports Source Type: research

Porphyromonas gingivalis infection modifies oral microcirculation and aortic vascular function in the stroke-prone spontaneously hypertensive rat (SHRSP)
The objective of this study is to analyze the vascular endothelial function of periodontitis and stroke animal models. We examined endothelial function and gingival blood flow in oral microcirculation in vivo and measured the isometric tension in vitro of the aorta in animal models for lifestyle-related diseases, such as periodontitis and stroke. Gingival reactive hyperemia (GRH) was measured using laser Doppler flowmetry. Wistar Kyoto rats (WKY) were used as control animals; Porphyromonas gingivalis (P. gingivalis) infected WKY (WKY + Pg) as the periodontitis model; stroke-prone spontaneously hypertensive rat (SHRSP) as t...
Source: Microbial Pathogenesis - December 25, 2015 Category: Infectious Diseases Source Type: research

An in vitro porcine model evaluating a novel stent retriever for thrombectomy of the common carotid artery
ConclusionsOur data indicated that RECO device was a novel, safe and effective stent based clot retriever. A phase IIa clinical trial, RESTORE, is undergoing (NCT01983644). © 2015 Wiley Periodicals, Inc.
Source: Catheterization and Cardiovascular Interventions - October 30, 2015 Category: Cardiovascular & Thoracic Surgery Authors: Yongjun Jiang, Yun Li, Xiaomeng Xu, Yongyi Yu, Wenhua Liu, Xinfeng Liu Tags: Peripheral Vascular Disease Source Type: research

O60. Treatment of hypertension in pregnancy
Conclusions According to recent guidelines, in the absence of randomised clinical trials recommendations how hypertension should be treated in pregnant women, can only be guided by experts’ opinion based on case reports and their meta-analyses.
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - August 31, 2015 Category: OBGYN Source Type: research

E-062 transradial access for acute interventional stroke therapy
ConclusionTransradial artery access for neuro-interventional procedures is rarely considered today. Our small case study suggests that transradial access is safe and efficacious in advance stroke therapy. Further studies with larger sample size are needed.DisclosuresJ. Farkas: None. K. Sivakumar: None. T. Sabharwal: None. H. Dababneh: None. A. Tiwari: None. K. Arcot: None.
Source: Journal of NeuroInterventional Surgery - July 26, 2015 Category: Neurosurgery Authors: Farkas, J., Sivakumar, K., Sabharwal, T., Dababneh, H., Tiwari, A., Arcot, K. Tags: SNIS 12th Annual Meeting Electronic Poster Abstracts Source Type: research

Reduced systemic vascular resistance is the underlying hemodynamic mechanism in nitrate-stimulated vasovagal syncope during head-up tilt-table test
Conclusions Presyncopal symptoms during NTG-stimulated HUTT are SVR mediated, not cardiac output mediated. This study challenges the conventional idea of a decrease in cardiac output mediated by NTG as the overriding cause of presyncopal symptoms during HUTT.
Source: Journal of Arrhythmia - May 3, 2015 Category: Cardiology Source Type: research

Which Hemodynamic Parameter Predicts Nitroglycerin‐Potentiated Head‐Up Tilt Test Response?
ConclusionsOur results show that, 2 minutes after nitroglycerin administration, a statistically significant decrease of SV values (<67 mL) strongly predicts (area under the curve, 0.985; P < 0.0001) the HUTT‐positive response in healthy patients with recurrent unexplained syncope.
Source: Pacing and Clinical Electrophysiology : PACE - February 14, 2015 Category: Cardiology Authors: VINCENZO RUSSO, ANDREA ANTONIO PAPA, CARMINE CIARDIELLO, ANNA RAGO, RICCARDO PROIETTI, PAOLO CALABRÒ, MARIA GIOVANNA RUSSO, GERARDO NIGRO Tags: ORIGINAL ARTICLE Source Type: research

Clevidipine: A Review of Its Use for Managing Blood Pressure in Perioperative and Intensive Care Settings
In conclusion, intravenous clevidipine is a valuable agent for the management of BP in perioperative and intensive care settings.
Source: Drugs - October 14, 2014 Category: Drugs & Pharmacology Source Type: research

Associations among cerebral microbleeds, cerebral large-artery diseases and endothelial function.
CONCLUSIONS: CMBs may coexist with cerebral atherosclerosis in ischemic stroke. Endothelial dysfunction may play a role in the pathogenesis of CMBs, but may not simply reflect functional alterations of large arteries. PMID: 25266513 [PubMed - in process]
Source: Chinese Medical Journal - September 1, 2014 Category: Journals (General) Authors: Peng Q, Huang Y, Sun W, Xing H Tags: Chin Med J (Engl) Source Type: research

The Case Files: When a Spade is Not a Spade
Turrin, Danielle DO; Sattler, Steven DO; Amodeo, Dana DO A 25-year-old Hispanic man presented to the emergency department with a complaint of three days of left-sided precordial chest pain. He described the pain as a constant 6/10 with pressure-like discomfort radiating to his left arm and the left side of his neck. He also experienced nausea, but denied any provocative or palliative factors. He said he had not experienced anything similar to this before. He had no family history of heart disease, acute myocardial infarction, or sudden cardiac death. He admitted to a 1.5 pack-per-day smoking history and social alcohol use,...
Source: The Case Files - August 26, 2014 Category: Emergency Medicine Tags: Blog Posts Source Type: research

Take common-sense steps to stay safe this summer
When the mercury rises, heat can strain the limits of the body's cooling system. Its driving engine, the heart, takes on a heavier load in hot weather to keep body temperature within norms, reports the July 2014 issue of the Harvard Men's Health Watch. For otherwise fit, active men, handling the heat requires no more than knowing their limits and drinking enough fluids. But what about men with heart conditions? "They are going to be more sensitive to the heat," says Dr. Joanne Foody, director of cardiovascular wellness services at Harvard-affiliated Brigham and Women's Hospital. "They may just need to limit their activitie...
Source: New Harvard Health Information - June 27, 2014 Category: Consumer Health News Source Type: news