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Anti-Vascular endothelial growth factor therapy impairs endothelial function of retinal microcirculation in colon cancer patients – an observational study
Conclusions
Bevacizumab acutely impairs microvascular function independent of blood pressure changes. Imaging of the retinal microcirculation seems a valuable tool for monitoring pharmacodynamic effects of bevacizumab.
Trial registration
NCT ID: NCT00740168
Source: Experimental and Translational Stroke Medicine - May 13, 2013 Category: Neurology Source Type: research