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Drug: Amphetamine

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Total 49 results found since Jan 2013.

Does smoking marijuana cause stroke?
1.5 out of 5 stars Cannabis-related Stroke: Myth or Reality? Wolff V et al. Stroke 2013 Feb;44(2):558-63. doi: 10.1161/STROKEAHA.112.671347. Epub 2012 Dec 27. No abstract available There have been scattered reports in the literature claiming an association between the use of cannabis and ischemia and/or hemorrhagic stroke. Although no convincing mechanism has been postulated, some suggest that use of marijuana or hashish and the occurrence of stroke may stem from the ability of cannabis to cause orthostatic hypotension, or possibly vasoconstriction. If such an association is real, it must be exceedingly rare. The purpose...
Source: The Poison Review - January 27, 2013 Category: Toxicology Authors: Leon Tags: Medical cannabis cerebral vascular accident hashish marijuana neurotoxicity stroke Source Type: news

Illicit Drug Related Acute Ischemic Stroke, The Impact of Age and Gender (P3.236)
Conclusions: Patient age and sex are poor predictors of illicit drug related acute ischemic stroke. There is underutilization of urine toxicology screening. Acute ischemic stroke standard labs should include urine toxicology screening.Disclosure: Dr. Alhatou has nothing to disclose. Dr. Kirkman has nothing to disclose. Dr. Siddiqui has nothing to disclose. Dr. Alhatou has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Alhatou, M., Kirkman, T., Siddiqui, H., Alhatou, A. Tags: Stroke in the Young Source Type: research

Unlabeled amphetamine isomer in sports supplement “probably” caused hemorrhagic stroke
3.5 out of 5 stars Hemorrhagic Stroke Probably Caused by Exercise Combined With a Sports Supplement Containing β-Methylphenylethylamine (BMPEA): A Case Report. Cohen P et al. Ann Intern Med 2015 May 12 [Epub ahead of print] Reference Last month, the FDA sent letters to 5 companies that manufacture so-called “dietary” or “sports” supplements, warning them that their products were mislabeled because they contained an unlisted ingredient. That ingredient, β-methylphenylethylamine (BMPEA), is an isomer of amphetamine. Although the effects of BMPEA in humans have not been well studied, it has been ...
Source: The Poison Review - May 22, 2015 Category: Toxicology Authors: Leon Tags: Medical amphetamine beta-methylphenylethylamine BMPEA dietary supplement hemorrhagic stroke sports supplement Source Type: news

Modafinil for the Improvement of Patient Outcomes Following Traumatic Brain Injury
Conclusion. Modafinil is a central nervous system stimulant with well-established effectiveness in the treatment of narcolepsy and shift-work sleep disorder. There is conflicting evidence about the benefits of modafinil in the treatment of fatigue and EDS secondary to TBI. One randomized, controlled study states that modafinil does not significantly improve patient wakefulness, while another concludes that modafinil corrects EDS but not fatigue. An observational study provides evidence that modafinil increases alertness in fatigued patients with past medical history of brainstem diencephalic stroke or multiple sclerosis. ...
Source: Innovations in Clinical Neuroscience - April 1, 2018 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Review excessive daytime sleep fatigue head injury modafinil stroke TBI traumatic brain injury Source Type: research

Risk of stroke in prescription and other amphetamine ‐type stimulants use: A systematic review
Conclusions. This is the first systematic review on ATS and stroke. Limited epidemiological evidence suggests that ATS use increases stroke risk. Possible disparities in ATS effect across stroke type and higher effect in women deserve further clarification. Studies on non‐medical ATS use should be a priority. [Indave BI, Sordo L, Bravo MJ, Sarasa‐Renedo A, Fernández‐Balbuena S, De la Fuente L, Sonego M, Barrio G. Risk of stroke in prescription and other amphetamine‐type stimulants use: A systematic review. Drug Alcohol Rev 2017;00:000–000]
Source: Drug and Alcohol Review - May 8, 2017 Category: Addiction Authors: Blanca Iciar Indave, Luis Sordo, Mar ía José Bravo, Ana Sarasa‐Renedo, Sonia Fernández‐Balbuena, Luis De la Fuente, Michela Sonego, Gregorio Barrio Tags: Comprehensive Review Source Type: research

The efficacy and safety of pharmacological treatments for post-stroke aphasia.
Conclusions Current evidence suggests that drugs can improve the prognosis of post-stroke aphasia, such as donepezil, memantine. Donepezil has a significant effect in improving the ability of auditory comprehension, naming, repetition and oral expression. Memantine has a significant effect in improving the ability of naming, spontaneous speech and repetition. Bromocriptine showed no significant improvement in the treatment of aphasia after stroke. The trial for galantamine, amphetamine and levodopa in the treatment of aphasia after stroke is limited and inconclusive. PMID: 29984673 [PubMed - as supplied by publisher]
Source: CNS and Neurological Disorders Drug Targets - July 6, 2018 Category: Drugs & Pharmacology Authors: Zhang X, Shu B, Zhang D, Huang L, Fu Q, Du G Tags: CNS Neurol Disord Drug Targets Source Type: research

Pharmacotherapy and motor recovery after stroke.
Authors: Viale L, Catoira NP, Di Girolamo G, González CD Abstract INTRODUCTION: Stroke is one of the most prevalent neurological diseases worldwide, especially among the elderly population. There are various mechanisms that enhance motor recovery after a stroke. In clinical practice, we have the opportunity to enhance plasticity by designing specific rehabilitation programs. Areas covered: There are a variety of drugs commonly administered to people after the acute phase of a stroke. These drugs may modify motor performance. Herein reviewed is the evidence concerning motor enhancement or decline in stroke patients, p...
Source: Expert Review of Neurotherapeutics - November 11, 2017 Category: Neurology Tags: Expert Rev Neurother Source Type: research

Neurobiology of amphetamine use in stroke recovery combined with rehabilitative training and brain stimulation
CNS Neurol Disord Drug Targets. 2022 May 12. doi: 10.2174/1871527321666220512155811. Online ahead of print.ABSTRACTStroke is a physiological disorder involving a prolonged local interruption of cerebral blood flow. It leads to massive neuronal death and causes short-term or long-lasting functional impairment. Most stroke victims regain some neural function weeks or months following a stroke, but this recovery can plateau six months or more after the injury. The goal of stroke therapy is the rehabilitation of functional capabilities, especially those affecting the patient's autonomy and quality of life. Recent clinical and ...
Source: CNS and Neurological Disorders Drug Targets - May 13, 2022 Category: Drugs & Pharmacology Authors: Mohammad Uzair Muhammad Arshad Turki Abualait Zeyad T Al-Harbi Talal M Al-Harbi Reem Bunyan Fahad Abida Arshad Woo Kyoung Yoo Shahid Bashir Source Type: research

Intracerebral Hemorrhage Associated with Oral Phenylephrine Use: A Case Report and Review of the Literature
Conclusions: It is scientifically plausible that phenylephrine may cause strokes, consistent with the pharmacologic properties and adverse event profiles of similar amphetamine-like sympathomimetics. As RCVS has been well described in association with over-the-counter sympathomimetics, a likely, although not definitive, causal relationship between phenylephrine and ICH is proposed.
Source: Journal of Stroke and Cerebrovascular Diseases - August 25, 2014 Category: Neurology Authors: Brian E. Tark, Steven R. Messe, Clotilde Balucani, Steven R. Levine Tags: Original Articles Source Type: research

Procedural learning as a measure of functional impairment in a mouse model of ischemic stroke.
Abstract Basal ganglia stroke is often associated with functional deficits in patients, including difficulties to learn and execute new motor skills (procedural learning). To measure procedural learning in a murine model of stroke (30min. right MCAO), we submitted C57Bl/6J mice to various sensorimotor tests, then to an operant procedure (Serial Order Learning) specifically assessing the ability to learn a simple motor sequence. Results showed that MCAO affected the performance in some of the sensorimotor tests (accelerated rotating rod and amphetamine rotation test) and the way animals learned a motor sequence. Th...
Source: Behavioural Brain Research - March 17, 2016 Category: Neurology Authors: Linden J, Beeck LV, Plumier JC, Ferrara A Tags: Behav Brain Res Source Type: research

Amphetamine and post-stroke rehabilitation: indications and controversies.
Abstract There is robust evidence for amphetamine (AMPH) facilitated recovery from behavioral deficits in animal models of stroke. Following experimental lesions, numerous studies of motor, somatosensory and vision recovery show AMPH accelerates the rate of recovery when paired with relevant behavioral experience. While the experimental literature continues to mount for an AMPH effect, the translation to clinical studies has been far less clear. This is due in part to the inherent difficulty of extrapolating results in animals to humans; however, there is much controversy regarding how the basic science data is in...
Source: European Journal of Physical and Rehabilitation Medicine - April 5, 2013 Category: Rehabilitation Authors: Walker-Batson D Tags: Eur J Phys Rehabil Med Source Type: research

Preworkout Supplement Induced Hemorrhagic Stroke: A Case Report
Abstract: Hemorrhagic stroke is a catastrophic cause of both long-term morbidity and mortality. Many risk factors for development of these strokes are in fact preventable or modifiable in nature. This case report outlines an incident involving a previously healthy 24-year-old man with no apparent risk factors apart from consumption of preworkout supplementation who developed a hemorrhagic stroke. The supplements that this particular patient was consuming included various potential causative agents—with the most significant being Dendrobium extract, which contains compound B-phenylethylamine, a precursor in the amphet...
Source: Clinical Journal of Sport Medicine - November 1, 2021 Category: Sports Medicine Tags: Case Report Source Type: research

The Amphetamine-Enhanced Stroke Recovery (AESR) Trial: Primary Part 1 Results (S45.003)
CONCLUSIONS:The studied treatment regimen was safe. Primary results will be presented.Study Supported by:NIH-NS39934Disclosure: Dr. Goldstein has received personal compensation for activities with Pfizer Inc. Dr. Goldstein has received royalty payments from Up To Date, Henry Stewart Talks, and Quantia. Dr. Goldstein has received research support from AGA. Dr. Rabadi has nothing to disclose. Dr. Reding has received personal compensation for activities with Acorda Therapeutics as a consultant. Dr. Lennihan has nothing to disclose. Dr. Good has received personal compensation for activities with Allergan, Inc. Dr. Good has rec...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Goldstein, L., Rabadi, M., Reding, M., Lennihan, L., Good, D., Dromerick, A., Pura, J., Samsa, G. Tags: Cerebrovascular Disease and Interventional Neurology: Rehabilitation, Recovery, and Complications Source Type: research